Endocrine Abstracts

Introduction: Pituitary somatotrop adenomas are very rare in children and adolescents. They are supposed to be more invasive (invasion of cavernous sinuses or meninges±compression of adjacent neural structures) than adults’ones. We aimed to analyze their characteristics, and their complications.Patients and subjects: are studied subjects whose clinical symptoms began before 20 years old. They all had biological, hormonal, ophthalmological, radi...

Introduction: Prolactinomas are more invasive in males. Giant (≥4 cm) and huge (≥6 cm) ones are relatively rare in literature, but in our population they are nearly common.Aim: We have taken our 20 last cases to analyze their radiological aspects, and their endocrine, neurological and ophthalmological complications.Methods: All of them had clinical exam, hormonal, ophthalmological, and radiological exploration based on ...

Glucose abnormalities are frequent in hyperthyroidism; the aim of our study is to determine the predisposing factors of glucose disturbances in hyperthyroidism.Subjects and methods: It is a retro and prospective study including 263 hyperthyroid subjects, patients having fasting glycaemia <1 g/l and/or glycaemia after OGTT <1.40 g/l (G1) were compared to patients having fasting glycaemia ≥1 g/l and/or glycaemia after OGTT ≥1.40 g/l (G2...

Primary empty sella (PES) is a frequent radiological entity in general population. The herniation of sub arachnoid space in the sella turcica can induce various visual and/or endocrine disorders. In this work we want to study first symptoms leading to diagnosis, clinical and paraclinical aspects of 36 adults with PES. Diagnosis of PES is made by TDM and/or IRM after exclusion of secondary empty sella. In this study empty sella is considered as complete in 51.5% cases and parti...

Cushing’s syndrome is rare in males. Hypercortisolic consequences on male gonadal function are unknown. The aim of our study is to research gonadal and sexual abnormalities in 17 male subjects with endogenous cortisol excess: 10 Cushing’s diseases, 5 paraneoplastic Cushing syndrome, 1 malignant corticosurrenaloma, 1 micronodular dysplasia. Their mean age is 30.2 years (18 – 50). Our work is based on anamnestic, clinical and hormonal results. Our population is co...

Cushing’s syndrome is rare in males. Hypercortisolic consequences on male gonadal function are unknown. The aim of our study is to research gonadal and sexual abnormalities in 17 male subjects with endogenous cortisol excess: 10 Cushing’s diseases, 5 paraneoplastic Cushing syndrome, 1 malignant corticosurrenaloma, 1 micronodular dysplasia. Their mean age=30.2 years (18–50). Our work is based an anamnestic, clinical and hormonal results. Our population is compare...

Introduction: Nowadays, thyroid Ultrasound (US) is a reference exam and the best way for detection, diagnosis and monitoring of thyroid nodules suspect of malignancy. It allows selection of suspicious thyroid nodules for malignancy.Our aim was to assess contribution of this exam using the TI-RADS score in order to establish the correlation with cytological results.Materials and methods: A prospective study of 395 pati...

Introduction: Nowadays, thyroid Ultrasound (US) is a reference exam and the best way for detection, diagnosis and monitoring of thyroid nodules suspect of malignancy. It allows selection of suspicious thyroid nodules for malignancy.Our aim was to assess contribution of this exam using the TI-RADS score in order to establish the correlation with cytological results.Materials and methods: A prospective study of 395 pati...

Introduction: Pituitary apoplexy is a rare endocrine emergency characterized by the sudden onset of severe headaches, vomiting, visual abnormalities and pituitary dysfunction secondary to an acute hemorrhage or infarction within a pituitary adenoma.Subjects and methods: We report a retrospective study from 2000 to 2014 of 23 cases with pituitary apoplexy. Their mean age was 38.7 years ±10 years, with a male to female ratio of 2:1. All patients benef...

Introduction: Primary thyroid lymphomas (PTL) are rare tumors, accounting for 2.5% of all non-Hodgkin’s lymphomas and fewer than 2% of all malignant thyroid tumors. Primary thyroid’s Burkitt lymphoma represents a very unusual type of PTL. Only very few cases of primary thyroid’s Burkitt lymphoma have been reported during pregnancy.Observation: We present a 30 years old female patient who developed a rapidly enlarging painless neck mass. Th...