Endocrine Abstracts

Introduction: Simultaneous pancreas-kidney transplantation remains the best treatment option in type 1 diabetic patients with chronic kidney failure, providing a euglycemic state associated with an improvement on diabetic chronic complications. However, there are only a few studies addressing the potential ischemic deterioration of peripheral arterial disease, due to blood diverting from the iliac artery to the kidney graft.Aim: Evaluate diabetic foot le...

Introduction: Primary hyperaldosteronism (PHA) and pheochromocytoma are endocrine causes of secondary arterial hypertension. The association of hyperaldosteronism and pheochromocytoma is rare and the involved mechanisms are poorly understood. Either there is coexistence of the two diseases (pheochromocytoma with PHA) or the pheochromocytoma stimulates the production of aldosterone.Case Report: Male, 54 years old, referred to our department for type 2 dia...

Introduction: About 5% of the adult population has adrenal incidentaloma(AI) and its incidence increases with age. AACE guidelines recommend image and hormonal evaluation during 5 years in non functioning AI. The european’s guidelines advise against repeat evaluation in non-secretory AI that present with <4 cm and had benign features. According to recent studies, the risk of developing clinically relevant hormone secretion is <0.3%, in patients with previous non-f...

Introduction: The quality of life (QoL) of patients with Diabetes has been the subject of several studies worldwide. In Portugal, studies have shown that patients under intensive insulin therapy had worse results in QoL questionnaires. The introduction of interstitial glucose monitoring (IGM) appears to reduce the impact of insulin therapy on QoL.Objective: To assess whether IGM changes the quality of life of patients with diabetes, compared to the asses...

Introduction: Diabetes is a disease with great psychosocial impact and reduced quality of life (QoL), and psychosocial factors seem to be excellent predictors of clinical outcomes.Objective: Assess the relationship between the patient’s perception of diabetes management and its impact on QoL.Methods: Interview of patients with type 1 (T1D) and type 2 diabetes (T2D), using the ‘Appraisal of Diabetes Scale’ (ADS), a qu...

Introduction: Obesity is a multifactorial and chronic disease. Bariatric surgery (BS) is the most effective treatment. A prevalence of 45% of esophagitis and 40%-70% of gastritis after BS has been reported. We analysed the presence of gastroesophageal lesions in patients who underwent BS (By-pass Roux-en-Y(BP) and gastric sleeve(GS)) in our centre.Methods: Patients submitted to BS between 2018-2020 were included. We retrospectively analysed clinical data...

Introduction: Inferior petrosal sinus sampling (IPSS) has been considered to be the gold standard for differential diagnosis of Cushing’s Disease (CD) and ectopic ACTH secretion (EAS).Aim: To describe the experience of our centre in performing IPSS, its safety and efficacy; assess remission rates from transphenoidal surgery and clinical course; approach to the difficulty in the etiological diagnosis of ACTH-dependent Cushing’s Syndrome.<p c...

Introduction: Thyroid nodules have a high prevalence in the adult population (20-76%). In 2018, the American College of Radiology proposed an ultrasound classification score of thyroid nodules - Thyroid Imaging Reporting and Data System-TIRADS, with 88% of sensitivity and 49% of specificity to predict malignancy. Since then, several studies report sensitivity values of 70.6-97% and specificity of 30-98%. We pretend to compared TIRADS score with cytologic results based on Bethe...

Introduction: Diabetes is the leading worldwide cause of chronic kidney disease, which is diagnosed by measuring albuminuria and estimating glomerular filtration rate (GFR) with creatinine-based formulas, such as the 2009 CKD-EPI developed in the United States of America (USA). Nonetheless, the race coefficient (RC), present in the 2009 CKD-EPI, may overestimate GFR in other countries.Aim: The goal of this systematic review and meta-analysis was to asses...

Introduction: Thyrotoxic crisis is a rare endocrinological emergency with high mortality and it is more frequent in Graves’ disease.Clinical case: A 66-year-old women with schizophrenia was admitted to the Emergency Department due to altered state of consciousness, fatigue, constant moaning interspersed with unusual psychomotor agitation, heteroaggressiveness, diarrhea and anorexia. Lack of compliance with her psychiatric medication, new delusional ...