Endocrine Abstracts

Introduction: Adult-onset noninsulinoma pancreatogenous hypoglycemia syndrome (NIPHS) associated with hyperinsulinemic hypoglycemia is a very rare entity. Clinical features of NIPHS are similar to those of insulinoma. Hypoglycemia with neuroglycopenic symptoms presents the main diagnostic condition. NIPHS is often poorly responsive or unresponsive to medical management necessitating surgical intervention with resection of pancreatic tissue.Case report: W...

Primary hyperparathyroidism is an autonomous form of hyperparathyroidism, whose characteristics are: increased secretion of parathyroid hormone with clinical signs of hypercalcemic syndrome and various organ lesions, including bones.Case report: A 51-year-old Caucasian female presented with walking difficulties, polyuria, polydipsia, palpitations and headaches. Examination showed thoracic spine hyperkyphosis with consecutive chest deformity, staggered wa...

Adrenal tumours form a very heterogeneous group by their origin, clinical presentation, size and biological potential.The aim of our retrospective study was the epidemiological analysis of the patients with adrenal tumours. We analyzed the gender, age, localisation, clinical presentation, and in patients who were treated surgically- the type of the intervention, patohystological and immunohystochemical finding from the 01.01.2000 to 01.01.2008. The linea...

Acromegaly is associated with cardiovascular diseases. Accelerated atherosclerosis may have important role in that. The aim of this study was to examine the presence of dyslipidemia, glucose control imapairment, inflamation and hypertension as risk factors for the development of atherosclerosis in acromegalic patients.Study group included 28 patients with acromegaly without lesions of thyroid, adrenal and gonadal axis. The examination was performed befor...

Background and aims: Foot lesions (amputations, ulcerations) are the consequence of neuro-vascular complications. Cardiovascular risk factors are similar for both. Thus, we carried out a prospective 5-year study to examine the effects of established complications and classical risk factors on mortality in diabetic patients.Materials and methods: During the previous 5 years we analyzed 244 patients attending a diabetes clinic. The International Working Gr...

Introduction: Biological casuses of levothyroxine (LT4) malabsorption are well known. Congestive heart failure, gastrointestinal diseases, pregnancy, medication or dietary interference are the most commonly known causes of poor oral absorption of LT4. However, when substitution therapy with LT4 fails we need to be more exploratory.Case description: Female, born in 1987, BH 164 cm, BW 73kg, in 2010 she was presented as M. Basedowi and in october 2011 near...

The paper shows the data on diabetes mellitus occurrence in the population of northern Kosovo and Metohija (local inhibitants and displaced person). The research comprises results of 42 495 examinations in Unit of Internal Diseases of Medical Centre in Kosovska Mitrovica in theperiod of January 2000–December 2002 (14 000 examinations on average, annualy). Diabetes was diagnosed and classified on the basis of the latest internationally recognazed criteria in 280 580, that ...

Introduction: A number of studies reported that almost every fifth patient with thalassemia hav e diabetes. Various factors could contribute to inadequate retrograde glycemic control in thalassemia patients co-existed with diabetes. According to published data, HbA1C seems to be an insufficient marker of the quality of diabetes control in thalassemia patients.Case report: We present a male 67 years old type 2 diabetes patient with disease history for 15 ...

Introduction: Congentital adrenal hyperplasia (CAH) comes to adult endocrinologist wheather as transition from pediatritian (Case 3) or as still without diagnosis (Case 1, 2, 4). The aim of this work is to describe typical forms of CAH initially sucessfuly treated with dexamethasone therapy.Case descriptions: Case 1: female, 1972y., presented in 1995y. (23y.) as severe hirsutism and infertility managed by team of gynecologists. She refus...

Introduction: It is indisputable importance of vitamin D for the preserved integrity of the skeleton and bone metabolism.The aim of the study was to analyse bone turnover parameters in relation to the vitamin D status in women with postmenopausal osteoporosis.Materials and methods: This study included a total of 195 postmenopausal women with osteoporosis. Osteoporosis is diagnosed by DXA scan of the spine and hip. Bone turnover mar...