Endocrine Abstracts

Background and aims: The aim of this study was to examine the prevalence of neuropathy and nephropathy in patients with type 2 (T2DM) complicated by proliferate retinopathy (PDR) and coronary artery occlusive disease (CAOD) treated with stent or bypass surgery.Materials and methods: Comparisons were made between 22 patients with T2DM and bypass or stenting of coronary arteries with normal fundoscopic finding (G1) and 21 age matched controls without diabe...

Introduction: The incidence of thyroid nodules is increasing. Fine-needle aspiration (FNA) of all thyroid nodules is unnecessary, but it is necessary to provide a more precise identification of those nodules that are potentially malignant in nature. In the literature there are several suggested systems for assessing malignancy of nodules in the thyroid gland.Objective: To determine the differences between EU and ACR TIRADS recommendation for fine-needle ...

Background and aims: After two decades of silence in classification system od type 2 diabetes there are some indices that the dibebtic retinopathy might be the sign for introduction of insulin therapy. The aim of this study was to examine associations between measures of diabetic foot in people with diabetes complicated by nonproliferative retinopathy (NPDR), maculopathy and proliferative retinopathy (PDR).Materials and methods: People were included had ...

Introduction: Hypogonadotropic hypogonadism(HH) is mandatory treated with testosterone (T). However, gonadotropin(hCG/FSH) administration might be the challenging optimal therapy.Case 1: Male, 23-y-old, hypophisectomy pp. adenoma hromophobum, one month later- FSH 1.5 U/L, LH 0.55 U/L. Primogonyl(hCG) test; testosteronemia: 0 day 0.069, 3 day 19.01 nmol/l. After 5 m in ejaculate no sperm. 5 m after introduction of hCG twice weekly 1,500 i.u. and FSH+LH 15...

The aim of this work is to present two patients with vitamin D deficiency and primary HPT.A 51-year old woman (first refer, 2009-jul) was operated for pathohistologically confirmed parathyroid (PT) adenoma seen by ultrasound (US) and scintigraphy (Sc). Patient treated for previous years for hypertension and depression. Calcium (Ca; mmol/l): 3.1; Creatinine (Cre; μmol/l): 67. The results will be shown in following order: pre-/postoperatively, 3rd mon...

Background and aims: The distribution of arterial occlusive disease is not fully explained in diabetes. The aim of this study was to examine the prevalence of CHD and PAD in diabetic patients complicated by abnormal test of distal autonomic function (Neuropad®) and large fibre neuropathy.Materials and Methods: 237 patients were analysed, M/F 111/126, age (mean±SD) 61.3±9.5years (ys), diabetes duration 16.4±10.6ys., type 1 n=22 (9.3%),...

Ghrelin is stored alongside glucagon in developing islet, although in a discrete cellular compartment, the pancreatic ε-cell. However, recent observations have shown a subpopulation of ghrelin/glucagon-double-positive cells in developing pancreas. The aim of the present study was to examine the developmental patterns of ghrelin- and glucagon-immunoreactive (ir) cells expression and possible co-localization of these hormones during human pancreas development. For this purp...

Background and Aims: The aim of our investigation was to evaluate the relationship between parameters of the metabolic syndroma (MSDR; NCEP/ATPIII Panel) in randomly selected diabetic patients (DM) with peripheral arterial occlusive disease (PAOD).Materials and Methods: diabetics, male 680 (49.7%), age (mean+SD) 52.6+14.4yrs. (16–84), were propectively examined using doppler examination and neuropathy disability scoring (NDS). PAOD was confirmed in ...

IntroductionNon-alcoholic fatty liver disease (NAFLD) is a component of metabolic syndrome (MetS). Hence, it is frequently associated with type 2 diabetes mellitus (T2DM). The low-grade inflammation associated with NAFLD usually explained the changes in serum iron metabolism. This study aims to assess the link between liver steatosis severity and serum iron, ferritin, and transferrin levels.Material and methods<p class="abstext...

Background: Past research suggests that diabetes mellitus, although with still insufficiently known mechanisms, has an effect on bone turnover.Objective of this study was to determine the level of bone metabolism parameters and vitamin D in women with postmenopausal osteoporosis and type 2 diabetes mellitus.: Material and methodsThe prospective study included 30 women with postmenopausal osteoporosis and type 2 diabetes mellitus an...