Endocrine Abstracts

Introduction: The effects of TSH and thyroid hormones on bone turnover are well-known. The aim of this study is to examine the influence of osteoporosis (Op) and cardiometabolic syndrome risk factors on bone mineral density (BMD) in the population of age-matched, normotensive and nondiabetic females.Material and methods: Cross-sectional study involved 76 females (average age 53±10 years), divided into three groups: hypo-, hyper-, and euthyroid. Pres...

Introduction: A link between diabetes and coronary heart disease is well-known. The aim of this study is to examine the influence of actual and retroactive diabetes regulation parameters (admission glycaemia and HbA1C value) on duration of hospital stay and clinical outcome of T2DM patients suffered from NSTEMI/STEMI.Material and methods: Cross sectional study involved 103 examinees with past history of T2DM actually hospitalised in CCU due to acute myoc...

Introduction: Literature data suggests increased fracture risk in women with diabetes mellitus type 2 but the underlying mechanism is not fully understood.Aim of the study was to analyse bone turnover parameters in women with DM2 and in healthy women with osteoporosis in menopause.Materials and methods: There were 76 participants out of wich 36 women with DM2. Average diabetes duration was 14.48±10.51 years with mean HbA1c 7.8...

Introduction: MTC originates from the parafollicular calcitonin secreting cells. One quarter of MTC patients have familial form of the disease with RET mutation.Case reports: First female patient underwent total thyroidectomy for MTC at the age 40. Further investigation showed elevated urinary catecholamine levels and MIBG scintiscan verified bilateral pheochromocytoma. Bilateral adrenalectomy was performed. On follow-up basal and stimulated calcitonin l...

Introduction: Although diagnostics and therapy are much improved over the years, women with gestational diabetes still have more adverse course and outcome of pregnancy than healthy women. Their pregnancies are more often complicated with the different forms of maternal and fetal morbidity. Our study investigates all cause early neonatal morbidity (neonatal jaundice, neonatal hypoglycemia, fetal distress syndrome and other) and newborns maturity and vitality in the groups of d...

Introduction: Diabetic retinopathy screening is the most accessible method of visualization of the affected small blood vessels in diabetic patients. Diabetic retinopathy is associated with age of patients, duration of diabetes, male sex, poor blood glucose control, central obesity, arterial hypertension, increased proteinuria, chronic inflammation and lipid disorders. Our study aims to compare type 2 diabetes patients with and without developed diabetic retinopathy regarding ...

Introduction: It is well documented that adrenal tumor tissue is responsive to human chorionic gonadotropin (hCG) as well as to luteinizing hormone (LH) with both hormones sharing a similar physiological role and a mutual receptor.Objective: The objective of our study was to assess the adrenal steroid response to acute, exogenous hCG stimulation in patients with adrenal incidenatalomas (AI) and for the first time, in a healthy control group.<p class=...

Transition from childhood to adulthood is a vulnerable period in all adolescents and particularly inCO-GHD patients. Low bone mineral density (BMD) and body composition alterations are frequently reported in young adults with CO-GHD, but relevant large monocentric studies are lacking.Patients and Methods: In a monocentric, observational, retrospective cross-sectional study conducted from 2005–2019, 107 CO-GHD patients were analyzed (17–26 yea...

Introduction: Epidemiological studies show that one half of vertebral fractures, which play an important role in estimation of future fracture risk, remain unrecognized.Aim: To establish vertebral fracture frequency in relation to bone mineral density in postmenopausal women.Methods: Study comprised 146 postmenopausal women. On the grounds of spine and hip DXA T-score based on WHO criteria subjects were divided to healthy,...

Introduction: Vertebral fragile fracture is risk factor for future vertebral and hip fractures.Aim: To establish prevalence of vertebral fractures using lateral DXA scan of thoracic and lumbar spine in women with postmenopausal osteoporosis.Method: Study comprised 73 women with postmenopausal osteoporosis diagnosed using spine and hip DXA. Vertebral fractures were verified by lateral DXA scan vertebral morphometry of thoracic and l...