Endocrine Abstracts

Purpose: Diabetic nephropathy is one of the leading causes of chronic kidney disease (CKD). Poor regulated glycemic control can result in progression of CKD. As diabetes mellitus (DM) and obesity can participate in development of atherosclerosis, the aim of this study was to assess the association of HbA1c and BMI in patients with CKD with intima-media thickness (IMT) as the early marker of atherosclerosis.Methods: This cross-sectional study included 88 ...

Background/Aim.: Importance of glucoreglation qality in diabetes complication prevention was proven in numerous clinical studies. Aim of this study is to determine impact of glucoregulation and duration of diabetes on the incidence of chronic complications of diabetes in Republic of Srpska (RS).Method: Study model included subjects with T1D and T2D who participated in the two-year project in the RS. It was a cross-sectional study with 10...

B-pancreatic cells are programmed to react to plasma glucose level with insulin secretion. Insulin secretion is precisely regulated and in the physiological conditions fasting glucose levels are maintained in the range 3.5–5.5 mmol/l. In hyperinsulinemic hypoglycemia, a disorder of the regulation of insulin secretion, insulin secretion continues at low concentrations of plasma glucose. In adults hyperinsulinemic hypoglycemia is the cause of 0.5 to 5.0% of hypoglicaemias a...

Introduction: Dietary therapy (DT), programmed physical activity (PPA) and cognitive-behavioural therapy (CBT) are basic measures in the treatment of obesity. CBT applies methods which change eating habits of obese persons, aiming to remove barriers relating DT and PPA. The goal of this study is to try efficiency of applying CBT in the programme for the reduction of body mass of obese persons, vs the application of DT and PPA alone.Design: The study incl...

Background /aim: Osteoporosis is a generalized bone disease, characterized by impaired bone firmness, resulting in an increased predisposition for fractures. In order to detect the subjects at risk for fractures, one should actively search for them, primarily in a group of postmenopausal women, considering clinical risk factors. Apart from others, the relevant risk factors are lack of estrogen and low body mass index (BMI <19 kg/m2).: The aim of this study was t...

Aim: To determine the effect of socioeconomic and educational status on metabolic control in T2D patients in Republic of Srpska (RS)Subjects and method: This is a cross–sectional study of 1088 subjects aged 18 or higher who were randomized from primary care physicians’ T2D diabetes registries. Socioeconomic, educational, anthropometric and metabolic characteristics of T2D patients were analyzed.Results: Highest proporti...

Aim: Chronic diabetes complications are the main cause of patients’ mortality, life span shortening and decreased quality of life. Aim of this study is to determine the incidence of chronic diabetic complications and their association with glucoregulation quality and antihyperglycemic treatment in diabetic patients in Republic of Srpska. (RS).Method: This cross–sectional study included 1037 diabetic patients in RS. Immuno–inhibition tes...

The effect of age on thyroid function and hypothalamic–pituitary–thyroid axis have been studied. The objective of the study was to examine: correlation between triiodothyronine (T3) and thyroxine (T4) hormone levels, thyroid antibodies and thyroglobulin levels and old age; capability of TSH and prolactin (PRL) response to TRH, in TRH test depending on age and gender of the examines. We have tested 125 subjects, classified in 4 group. First, cont...

Introduction: In order to detect the subjects at risk for osteoporotic fractures, one should actively search for them, primarily in a group of postmenopausal women, considering clinical risk factors. Body mass index (BMI) is a well-known, significant predictor of bone mineral density (BMD) of entire skeleton.Aim: The aim of this study was to examine relationship between BMI and BMD in a group of postmenopausal women.Methods: The st...

Introduction: Depression often occurs as comorbid and concomitant disorder in patients with type 2 diabetes (T2D) complicating the course and outcome of the disease, prolonging the treatment and accelerating complications of diabetes, especialy cardiovascular complications. Numerous researches show significant presence of cardiovascular disorders in depressed patients with T2D that show up several year after first depressive episode. Mortality caused by cardiovascular disorder...