Endocrine Abstracts

Introduction: Sheehan syndrome represents a rare cause of hypopituitarism. It results from postpartum ischemic necrosis of the pituitary gland. Data evaluating the quality of life in women with Sheehan syndrome are scarce. The aim of this study was to assess the quality of life in patients with Sheehan syndrome and to determine its associated factors.Methods: A cross-sectional study including women with Sheehan syndrome was conducted in the department of...

Introduction: – Sheehan syndrome (SS), or postpartum pituitary necrosis, is a rare but potentially serious complication of postpartum. – SS remains an important cause of hypopituitarism in Morocco.– The aim of this study is to evaluate the metabolic profile of patients with SS.Materials and methods: – This is a retrospective descriptive study conducted in the endocrinology department, spread over a period of 12 years, between the year...

Introduction: Sheehan’s syndrome is a rare postpartum complication. Recurrent hypoglycaemia,though described is a rare complication of Sheehan syndrome. Here we report a case of Sheehan syndrome which presented with hypoglycemic coma.Case Presentation: We report the case of a 47-year-old woman who presented to the medical emergency unit with coma. There was no history of chest pain, fever, headache, vomiting, trauma, or seizures. She had no history ...

Sheehan is an Interesting disease; post-partum bleeding can cause dangerous pituitary gland necrosis. Sheehan’s syndrome is a well-known condition that is generally diagnosed several years postpartum or can present acutely. Hypopituitarism after diagnosis of Sheehan syndrome can be present in insidious ways and there may be delay to diagnosis of over a decade because symptoms are often vague and pituitary dysfunction progresses gradually. We presented the case of hypopitu...

Introduction: Sheehan’s sydrome was known varying degrees of hypopituitarism due to postpartum ischemic necrosis by different etiologies. We report two case who are presented with pancytopenia which is unusual and rarely observed an important clinical finding associated with Sheehan’s syndrome.Case 1: A 57-year-old woman has complaints of malaise, fatigue, and dyspnea without lymphadenopatia and hepatosplenomagaly. She had excessive bleeding af...

Introduction: Sheehan syndrome has been for a long time the most frequent cause of hypopituitarism among women in developing countries, including Tunisia. Apart from hormonal deficits caused by SS, young women with SS are exposed to an increased risk of cardiovascular mortality. In this study, we aimed to evaluate the cardiovascular risk in patients with SS. Patients and methods This is a descriptive cross-sectional study. It was carried out in the Endocrinology department of ...

Sheehan syndrome is a global or partial pituitary defect occurring after an obstetrical haemorrhage.The aim of this study is to describe metabolic complications in 46 consecutive patients with Sheehan syndrome and to determine correlations between these complications and the clinical, hormonal and therapeutic aspects of this syndrome.All patients have had a physical examination: weight measurement, body mass index (BMI) determinati...

Background: Sheehan’s syndrome (SS) is rarely encountered in developed countries due to advanced obstetric care but it is still frequent and a major threat to women in developing nations. Anaemia among other risk factors may increase the risk of Sheehan’s syndrome.Case report: 36 year old woman, known sickle cell disease (SCD) patient with previous history of stroke in childhood, presented to the heamatologists on account of generalized body we...

Introduction: Sheehan’s syndrome is hypopituitarism occurring due to pituitary infarction secondary to severe post-partum haemorrhage. Here, we are presenting an interesting case history of Sheehan’s syndrome diagnosed 15–20 years after its onset.Case history: A 47-year-old lady attended emergency room (ER) with recurrent episodes of nausea, vomiting and dizziness on standing. Initial evaluation revealed hypotension and the random...

Introduction: Although the cause and effect relationship between the hypophyseal deficiency and osteoporosis is known well, the number of studies concerning bone mineral density (BMD) in patients with Sheehan’s syndrome (SS) are scarce. We aimed to investigate the relationship between BMD and deficient hormones in patients with newly-diagnosed Sheehan’s syndrome.Material and methods: Thirty-four patients with SS and age-gender-weight matched 22...