Endocrine Abstracts

Objectives: The aim of present study is to determine psychobiological characteristics of sexual dysfunction (SD) associated with metabolic syndrome (MS; as defined by National Cholesterol Education Program’s Adult Treatment Panel III, NCEP-ATP-III criteria) in a consecutive series of 803 male out-patients.Methods: Several hormonal, biochemical and instrumental (penile doppler ultrasound, PDU) parameters were studied, along with psycho...

Introduction: Primary adrenal lymphoma is rare, representing less than 1% of non-Hodgkin lymphomas.1 The clinical presentation is non-specific, symptoms of adrenal insufficiency may occur with bilateral lesions, and work up can be tricky.2Background: A 60-year-old man was admitted mid-January 2020 for acute left abdominal pain. He had no medical history and didn’t smoke or take any medication. He had no history of recent trauma...

We present the case of an octogenarian with a major history of lambda light chain myeloma which was treated by a first-line lenalidomide and dexamethasone from June 2018 to September 2019. Patient had also hypertension and valvular heart disease (mechanical valve and anticoagulation by acenocoumarol). In September 2019, a right adrenal mass was incidentally discovered by a renal ultrasonography made for acute kidney injury. The abdominal CT-scan confirmed the presence of a lar...

Objectives: Genomic instability play a role in cancer development through different mechanisms including chromosome fragility and in particular the altered telomere length (TL). Previous studies showed that the presence of short telomeres in the blood was associated with development of sporadic head and neck, bladder, lung, renal and breast cancer. In thyroid cancer, has been demonstrated that familial form of papillary thyroid cancer (FPTC) has shorter telomeres in blood leuk...

Objective: Recent studies have shown that sarcopenia at cancer diagnosis is associated with a poor survival in patients with solid tumors. Up to now, few data are available among patients with advanced thyroid cancer, especially those treated with tyrosine kinase inhibitors (TKI). We retrospectively evaluated sarcopenia by Skeletal Muscle Index (SMI) in a cohort of advanced thyroid cancer patients before and during TKI treatment and investigated its association with treatment ...

Introduction and Objective: The initial assessment of differentiated thyroid cancer (DTC) patients is based on the American Thyroid Association (ATA) risk stratification criteria. Dynamic risk stratification (DRS) of DTC patients takes into consideration the response to initial treatment being reassessed at 1–2 years and revealed significant shifts in the risk categories of DTC patients. We aimed to evaluate the long-term outcome of papillary thyroid cancer (PTC) patients...

Objectives: Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are characterized by insulin resistance and often associated with male hypogonadism. To discriminate the specific contribution of T2DM and MetS to male hypogonadism.Design and methods: A consecutive series of 1134 (mean age 52.1±13 years) male patients with sexual dysfunction was studied. Several hormonal and biochemical parameters were studied along with ANDROTEST, a 12-item ...

Objectives: The aim of present study was to verify possible differences in the prevalence of vasculogenic ED and hypogonadism comparing two distinct new definitions of MetS, as National Cholesterol Education Program-Third Adult Treatment Panel (NCEP-ATPIII) and International diabetes Federation (IDF) in patients with sexual dysfunction.Methods: Several hormonal, biochemical and instrumental (penile doppler ultrasound) parameters were studied. ANDROTEST S...

Objectives: Detecting hypogonadism is crucial in patients with sexual dysfunctions because hypogonadism can have a causal role for them and testosterone (T) substitution represents a milestone for the therapy. At present, three different inventories have been developed for screening of hypogonadism in aging male. All these instruments demonstrated a good sensitivity but low specificity. No inventories are available for the screening of hypogonadism in patients with sexual dysf...

Objectives: To date it is not clear to which extent a clinical, or even a subclinical, sexual dysfunction in the female partner might associate with erectile dysfunction (ED) in the male partner. The present study is aimed at the assessment of clinical features of ED associated with relational disturbances.Methods: In a consecutive series of 1140 male subjects reporting a stable couple relationship we evaluated the impact of relational factors, as assess...