Endocrine Abstracts

Introduction: Immune checkpoint inhibitors are relatively new and promising treatments for a variety of solid tumors. Nivolumab is an anti-cancer monoclonal antibody that inhibits anti-programmed death-1 (PD1) and modulates T-cell response. It has been shown to significantly improve survival in many types of cancer, but clinical studies have also reported an increased risk of developing immune-related adverse events. In particular, immune-related adverse events may be related ...

A 36 years of old patient was admitted to the intensive care unit of cardiology when he experienced palpitations and orthopnea. The patient’s complaints started about 2 years ago as syncope and sudden shortness of breath. Thorax CT showed pleural effusion and increased cardiothoracic index. Findings on ECHO were : Ejection fraction 35%, severe mitral regurgitation and global hypokinesia. Coronary angiogram showed a fibrocalcific plaque noted in in the distal LAD. The pati...

IntroductionPituitary adenomas secreting TSH (TSHoma) are a rare cause of hyperthyroidism. They account for approximately 0.5–3 % of functioning pituitary tumours and much less than 1% of all cases of hyperthyroidism. TSHoma should be considered in all hyperthyroid patients, especially those with diffuse goitre and no extrathyroidal signs of Graves’ disease.Case 1A 30-year-old female applied to the ...

BackgroundPituitary xanthogranulomas are extremely rare tumors of the sellar region. A cystic mass lesion was found in the pituitary MRI of our patient diagnosed with central diabetes insipidus (DI). We aimed to present a case who was operated for a pituitary mass and diagnosed with sellar xanthogranuloma.Case presentation37-year-old female patient was applied to our outpatient clinic with complaints of polyd...

Patient is a 43 years old female without any known additional disease. A pituitary mass was seen in the cranial MRI taken due to the complaint of forgetfulness. Pituitary MRI of the patient revealed a ’large intrasellar mass of 3.2x3x2.3 cm, which expanded the sella and pressed the optic chiasm’. The patient didn’t describe any symptoms other than forgetfulness. She didn’t have galactorrhea, cushingoid or acromegaloid appearance. Patients laboratuary evalua...

Objective: While postoperative hypoparathyroidism can usually be controlled with elemental calcium (Ca) and calcitriol therapy, rarely this treatment may be inadequate and teriparatid therapy may be used as an alternative. In the literature, it is reported that teriparatid therapy is effective and reliable in the treatment of patients with postoperative hypoparathyroidism, as well as improving quality of life and reducing the frequency of hospitalization. In this report, we pr...

BackgroundPrimary thyroid lymphoma (PTL) is defined as a lymphoma involving only the thyroid gland or the thyroid gland and adjacent (regional) neck lymph nodes. Primary lymphomas of the thyroid are uncommon tumours, representing approximately 5% of the thyroid neoplasms and 2% of extranodal lymphomas. The most characteristic presentation is that of a rapidly enlarging neck mass often associated with dysphagia [5]. The majority of patients are euthyroid ...

Purpose: In previous studies, magnesium (Mg) was found to be lower in cases with more severe primary hyperparathyroidism (PHPT) and higher calcium (Ca) levels. This study evaluated the relationship between serum Mg and serum Ca and phosphorus (P) levels in PHPT and their utility in discriminating osteoporosis and nephrolithiasis.Methods: Patients who were followed up with PHPT between March 2019 and March 2023 were analyzed retrospectively. Biochemical d...

Aim: Dry eye syndrome(DES) is a common finding in patients with thyroid orbitopathy. There are few studies on DES in patients with papillary thyroid cancer (PTC). Retinal pathology may develop in case of vitamin E deficiency, which has antioxidant, anti-inflammatory and anti-apoptotic properties.Materials and Methods: In our study, 29 patients who received radioactive iodine (RAI) treatment (Group 1) and 22 patients who did not receive RAI treatment (Gro...

Introduction: An insulinoma is a neuroendocrine tumor, deriving mainly from pancreatic islet cells, that constantly produces insulin even when blood sugar is very low. Insulinomas are the most common cause of hypoglycemia resulting from endogenous hyperinsulinism. Biochemical diagnosis of insulinoma is established during prolonged fasting test (up to 72 hours) in 95 % of patients, 90-95% of insulinomas can be diagnosed during 48 hours of prolonged fasting. After biochemical co...