Endocrine Abstracts

Introduction: Cushing’s disease (CD) is responsible for 80% of endogenous Cushing’s syndrome (CS). However, distinguishing the cause of ACTH-dependent CS – CD vs ectopic CS – can be extremely difficult. Bilateral inferior petrosal sinus sampling (IPSS) has the highest diagnostic accuracy in this evaluation.Objectives: The aims of this study were to determine the accuracy of bilateral IPSS in the differential diagnosis of ACTH-dependen...

Introduction: Poor metabolic control in type 1 diabetes mellitus (T1DM) is associated with micro and macrovascular complications. The implementation of interstitial glucose monitoring systems has contributed to the improvement of glycemic control in recent years.Objectives: Our main objective was to analyze the results of implementing flash glucose monitoring (FGM) devices after 1 year, and see if it managed to improve glycemic control in our patients.</...

Graves’ disease is one of the multiple autoimmune diseases that have been reported in HIV-infected patients. With the upsurge of highly active anti-retroviral therapy (HAART) the incidence of autoimmune diseases in HIV-infected patients is increasing, especially after immune reconstitution. We present a male, 51-year-old, who started complaining with anxiety, sudoresis and palpitations. The laboratory workout revealed hyperthyroidism: TSH <0.02 μU/ml (0.46–4...

Introduction/Objectives: Emphysematous osteomyelitis is a rare disease, characterized by the presence of intraosseous gas associated with an infectious process. It occurs in patients with chronic pathologies such as diabetes mellitus, and has high mortality. The most common location is the vertebral, sacral, femur, pelvis, tibia and fibula, while it is extremely rare in the foot.Material/Method: With the help of the Radiology service of our hospital, we ...

Introduction: The main purpose of this case is to present a case in which the left kurtosis interval of the fertile phase curve, may be evaluated by cheeking the biophysical changing pattern of reproducible methods of viscoelasticity and transparency of the cervical secretion.Case report: This case report included a 24 years old woman who plots a curve in which integrates two biomarkers in relation to the fertile window at the follicular phase. It was re...

Introduction: Gestational diabetes mellitus (GDM) is the metabolic disorder most frequently associated with pregnancy, presenting important maternal and fetal implications. Strict glycemic control through lifestyle measures and/or pharmacotherapy is essential to achieve adequate obstetric-perinatal results. The objective of this study is to compare baseline characteristics and perinatal results in patients diagnosed with GDM after performing oral glucose tolerance test (OGTT) ...

Introduction: In May 2020, during the COVID-19 pandemic, the Spanish Group of Diabetes and Pregnancy published a consensus document establishing the alternative diagnostic criteria for gestational diabetes mellitus (GDM) in case of impossibility to perform the two-step traditional approach due to the COVID-19 sanitary emergency. This study aims to compare different characteristics of pregnant women who tested positive in the O’Sullivan test in the same pregnancy trimester...

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

Metabolic syndrome and insulin resistance persist 5 years after remission of Cushing’s syndrome (CS). Adiponectin and visfatin are two adipokines highly expressed in adipose tissue. Adiponectin is reduced in obesity and insulin-resistant states; visfatin has been shown in some studies to be reduced in obesity. The aim was to evaluate visfatin and adiponectin levels, body composition, insulin resistance and prevalence of metabolic syndrome in a cohort of women with long-te...

Introduction: Low testosterone serum levels are associated with increased mortality in non-diabetic males. However, knowledge about the association between male hypogonadism and mortality among type 2 diabetic (T2DM) men is limited due to short follow-up periods in the few existing studies.Objective: To assess the association between hypogonadism and mortality in diabetic men.Material and methods: 263 unselected men with T2DM (mean...