Endocrine Abstracts

Objective: To measure the levels of 25-hydroxyvitamin D (25(OH)D) and vitamin D binding protein (VDBP) and assess their relationships with metabolic features in patients with the polycystic ovary syndrome (PCOS).Methods: 267 women, aged 20–35 years (24.7±4.9): 167 with PCOS, 100 healthy women as a control group were studied. Study groups were divided according to body mass index (BMI). Biochemical and hormonal parameters, 25(OH)D, VDBP were mea...

Polycystic ovary syndrome (PCOS) and type 1 diabetes (T1DM) are accompanied by increased risk of atherosclerosis. A higher prevalence of PCOS in T1DM patients has been reported. Brachial artery flow-mediated dilatation (FMD) and intima media thickness of common carotid artery (IMT) are used to detect an early endothelial dysfunction.The aim of our study was to examine IMT and FMD in T1DM women with PCOS. We also estimated the relation of IMT and FMD to c...

Introduction: Anthropometric parameters are easy and quickly methods of assess risks of many diseases.Aim: The purpose of this study was to assess the correlation between calf circumference index, selected anthropometric (such as BMI, BAI, WHR, WHtR index) and biochemical parameters (such as concentration of 25(OH)D3, lipid profile, fasting glucose) among patients over 60 years.Materials and methods: Cross-sectional study was done ...

Purpose: Recent reports strongly suggest that at least some cases of Hashimoto’s thyroiditis (HT) may be closely associated with IgG4-related disease. In the present study we aimed to find out, whether the measurement of serum IgG4 allows for an identification of distinct types of HT, with different clinical, sonographic and serologic characteristics.Methods: The group studied consisted of 53 patients with HT and 28 healthy individuals. All the part...

Introduction: Hormonal changes during menstrual cycle among women without hormonal contraception could probably influence the food intake. Sex hormones modulate body energy expenditure by affecting hypothalamus neurohormones.Aim: The aim of the study was to assess the way of nutrition among menstruating women without hormonal contraception, depend of menstrual cycle.Materials and methods: 77 menstruating women in age 19–26 ent...

Introduction: Sex hormones, such as estrogens or progesterone may have, both directly and indirectly, an influence on the appetite changes in. In addition, exogenous sex hormones are commonly used as one method of contraception.Aim: The purpose of this study was to assess whether the eating style in a group of menstruating women, taking oral hormonal contraceptives, is different in the individual menstrual cycle phases.Material and...

Introduction: Vitamin D is important for proper functioning of all body tissues. Receptors for vitamin D are also presence in thyroid gland. It’s open questions how this vitamin could modulate the thyroid function.Aim: The aim of the study was assess the concentrations of vitamin D as well as antiTPO level among patients with thyroid dysfunction hospitalised on Endocrinology Department.Materials and methods: The study was cond...

Introduction: Active metabolites of vitamin D have pleiotropic influence on whole body.Aim: The aim of the study was evaluation of the correlation between vitamin D3 and TSH values in population over 65.Materials and methods: 94 patients admitted to diagnosis on Geriatric Department entered the study. People with age above 65 were included to research and divided on two groups according to sex. The material samples were obtained fr...

Introduction: Anthropometric parameters such as: waist circumference, hips circumference, or arm circumference allow to find a correlation between the obesity and the risk of some metabolic disturbances (for example arm circumference index of upper part indicates the level of protein storage in the body).Aim: The aim of the study was to assess the correlation among the arm circumference index, concentration of 25-OH vitamin D3 and lipid profile parameter...

Genetic instability, i.e. loss of heterozygosity (LOH) and microsatellite instability (MSI) represent molecular disorders acquired by the cell during neoplastic transformation. Genetic instability is a frequent molecular event in thyroid pathogenesis, found at the early and the late stages of thyroid tumorigenesis. In thyroid neoplasms genetic instability was found in many chromosomal regions and is observed especially in cell-derived thyroid tumours. Alterations in PTEN loci ...