Searchable abstracts of presentations at key conferences in endocrinology

ea0073oc10.1 | Oral Communications 10: Thyroid | ECE2021

The role of VEGF expression in the development of papillary thyroid carcinoma in patients with lymphocytic thyroiditis

Gulcelik Nese Ersoz , Akın Şafak , Aydin Kadriye , Aydin Mericö Cisel , Usman Aydan

BackgroundVascular endothelial growth factor (VEGF) has been implicated in angiogenesis of papillary thyroid carcinoma (PTC). As VEGF expression is increased in PTC and even in lymphocytic thyroiditis (LT), we hypothesized that VEGF may play a role in the development of PTC in patients with LT. In order to find an association between VEGF and these disorders, we examined both the tumoral and adjacent tissues of PTC patients with and without LT.<p cla...

ea0032p1006 | Thyroid (non-cancer) | ECE2013

Prevalance of GH deficiency in Turkish patients with Hashimoto's thyroiditis: a single center experience

Akin Safak , Aydin Kadriye , Gurlek Alper

Background and Aim: Prevalence of Hashimoto’s thyroiditis is increasing in Turkey. GH deficiency has been reported to associate with this disorder in several different ethnic population. The aim of this study was to evaluate GH deficiency in the population with Hashimoto’s thyroiditis.Materials and methods: Euthyroid Hashimoto’s thyroiditis patients, who admitted to the Department of Endocrinology and Metabolism of Hacettepe University, we...

ea0032p593 | Female reproduction | ECE2013

Low dose oral contraceptive use and the risk of thrombosis in polycystic ovary syndrome

Akin Safak , Cinar Nese , Aydin Kadriye , Akman Umit , Buyukasik Yahya

Background and aim: Oral contraceptives (OC) are the mainstay of long-term treatment for women with polycystic ovary syndrome (PCOS). OC use is associated with increased risk of venous thromboembolism. The aim of the present study was to determine whether treatment with a low dose OC induce changes on coagulation and fibrinolysis in women with PCOS.Materials and methods: Sixteen lean, normal-glucose tolerant patients with PCOS (mean age, 22.4±2.4 ye...

ea0056p1023 | Thyroid (non-cancer) | ECE2018

Percutaneous ethanol injection for benign cystic and mixed thyroid nodules

Ozderya Aysenur , Aydin Kadriye , Gokkaya Naile , Temizkan Sule

Background/aim: We aimed to determine the effect of percutaneous ethanol injection (PEI) on volume of cystic and mixt thyroid nodules, thyroid function tests (TFTs), antibody titers and cytological changes for 1 year.Methods: Fifty-five nodules of 53 patients with cystic and mixt properties treated with PEI were included. Nodule volumes, TFTs, thyroid autoantibodies were analyzed at baseline, 6th and 12th months. Fine needle aspirat...

ea0049ep289 | Calcium &amp; Vitamin D metabolism | ECE2017

The results of parathormone assay in parathyroid aspirates in preoperative localization of parathyroid adenomas for focused parathyroidectomy in patients with negative or suspicious sestamibi scans

Ozderya Aysenur , Temizkan Sule , Cetin Kenan , Ozugur Sule , Gul Aylin Ege , Aydin Kadriye

Objective: In primary hiperparathyroidism (PHPT), increasing the number of patients treated by focused parathyroidectomy should be the main objective of pre-surgical imaging modalities. Suspicious or negative imaging results do not always mean multiglandular disease, most of the patients may single adenoma and therefore these patients may still benefit from focused parathyroidectomy.Methods: Retrospectively, we analyzed the data of 65 patients with PHPT ...

ea0037ep593 | Obesity and cardiovascular endocrinology | ECE2015

Is there a relationship between parathyroid hormone and obesity-linked disorders

Temizkan Sule , Demir Sevin , Aydin Kadriye , Ozturk Hilal Toplu , Ozderya Aysenur , Sargin Mehmet

Introduction: Accumulating evidence indicate that high PTH resulting from primary or secondary hyperparathyroidism, is associated with hypertension, insulin resistance, dyslipidaemia, obesity, and cardiovascular mortality. Here, we aimed to show whether high PTH levels in obese population contribute the metabolic complications of obesity.Methods/design: The medical records of all subjects attending the obesity outpatient clinic of Kartal Dr Lutfi Kirdar ...

ea0037ep948 | Thyroid (non-cancer) | ECE2015

High circulating levels of SICAM-1 and SVCAM-1 in patients with Hashimoto's thyroiditis

Ozderya Aysenur , Aydin Kadriye , Temizkan Sule , Abbasoglu Semra Dogru , Vural Pervin , Altuntas Yuksel

Objective: Elevated levels of the soluble adhesion molecules, sICAM-1 and sVCAM-1 reflect chronic inflammatory state. Increased levels of sICAM-1 and sVCAM-1 were demonstrated in various autoimmune thyroid diseases with abnormal thyroid function, but their clinical significance is undefined, especially in the euthyroid patients with Hashimoto’s thyroiditis (HT). Increased levels of soluble adhesion molecules are also associated with components of the metabolic syndrome li...

ea0032p369 | Diabetes | ECE2013

Relation of serum chemerin level with markers of atherosclerosis in diabetes and prediabetes

Aydin Kadriye , Canpolat Ugur , Dural Muhammet , Akin Safak , Karakaya Jale , Aytemir Kudret , Gurlek Alper

Introduction: Chemerin is a novel adipokine that is correlated with adipocyte differentiation, glucose metabolism and inflammation, but its role remains to be elucidated in atherosclerosis particularly in diabetes and prediabetes. We aimed to investigate the relation of serum chemerin levels with markers of atherosclerosis as exemplified by pulse wave velocity (PWV), carotid intima media thickness (CIMT), and carotid plaque presence in these groups.Metho...

ea0026p444 | Thyroid (non cancer) | ECE2011

Regulation of visceral adipose tissue-derived serin protease inhibitor in overt and subclinical hypothyroid patients

Cinar Nese , Gulcelik Nese Ersoz , Aydin Kadriye , Akin Safak , Usman Aydan , Gurlek Alper

Introduction: Visceral adipose tissue-derived serine protease inhibitor (vaspin) is a novel adipocytokine which might exert an insulin-sensitizing effect. It is thought that vaspin mRNA expression may be a compensatory mechanism associated with obesity and insulin resistance. Given the fact that subclinical and overt hypothyroidism are known risk factors for insulin resistance, we aimed to assess the regulation of vaspin by thyroid hormones in humans.Met...

ea0056gp83 | Diabetes Epidemiology | ECE2018

Prevalence and predictors of gestational diabetes mellitus: a nationwide multicenter prospective study

Aydin Hasan , Celik Ozlem , Yazici Dilek , Altunok Cigdem , Tarcin Ozlem , Deyneli Oguzhan , Sancak Seda , Kiyici Sinem , Aydin Kadriye , Yildiz Bulent Okan

Aim: Gestational diabetes mellitus (GDM) is an important public health issue associated with significant short- and long-term morbidity both for mother and offspring. Prevalence rates of GDM show considerable variation among different countries and regions of the world. The primary aim of this study was to determine the nationwide prevalence and predictors of GDM in Turkey.Materials and methods: We conducted a prospective nationwide screening among pregn...