Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep149 | Calcium and Bone | ECE2022

Bone mineral density in patients with addison disease versus congenital adrenal hyperplasia

Lavrador Mariana , Araujo Barbara Filipa , Carreira Ana , Paiva Sandra , Barros Luisa , Paiva Isabel

Introduction: The treatment of Primary Adrenal Insufficiency involves the chronic use of glucocorticoids. The balance between the dose needed to supply the cortisol deficit and the possible consequences of overtreatment is a challenge. In patients with Addison disease (AD), androgens deficiency is an additional factor for osteoporosis.Objective: To evaluate if there are differences in bone mineral density (BMD) in patients with Addison’s disease ver...

ea0081ep165 | Calcium and Bone | ECE2022

Reduced bone mineral density in primary adrenal insufficiency: consequences of long-term treatment

Araujo Barbara Filipa , Lavrador Mariana , Araujo Catia , Ferreira Mafalda , Barros Luisa , Paiva Sandra , Paiva Isabel

Introduction: The effects of long-term replacement therapy of primary adrenal insufficiency (PAI) are still a matter of debate. Glucocorticoid (GC) replacement regimens do not completely mimic the endogenous hormonal production and their monitoring is sometimes difficult. Therefore, some patients are exposed to mild GC excess with potential complications, such as hypertension, diabetes, and skeletal fragility. Data on bone mineral density (BMD) in PAI is still scarce and contr...

ea0041ep554 | Diabetes therapy | ECE2016

Economic impact on the use of insulin pumps in diabetes type I – analysis on Portuguese real life results

Joaquim Ines , Vilaverde Joana , Barros Luisa , Diniz Isabel , Sabino Filipa , Boavida Jose Manuel , Cardoso Helena

Although, diabetes type I patients in Portugal have complete and free access to HbA1c management (via multiple daily injections) only a few percentage has been provided an insulin pump – priority is given to children and women in fertile age trying to get pregnant. By the end of 2014, 1.150 insulin pumps had already been provided by the National Program of Insulin Pumps, but at least 3.000 patients with indication for insulin pump use were in waiting list. HbA1c pre-pump ...

ea0037ep512 | Diabetes (complications & therapy) | ECE2015

Continuous subcutaneous insulin infusion decreases hypoglycaemia during nighttime

Vicente Nuno , Cardoso Luis , Baptista Carla , Barros Luisa , Guelho Daniela , Oliveira Diana , Martins Diana , Carrilho Francisco

Introduction: Continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) are forms of intensified insulin therapy and the most used regimens for type 1 diabetes (T1D). Owing to its continuous basal output, hypoglycaemic events tend to be rarer with CSII. Our goal was to evaluate the differences in nocturnal hypoglycemia between these two treatment strategies.Methods: Retrospective analysis of 61 patients who had performed continu...

ea0035p328 | Clinical case reports Thyroid/Others | ECE2014

Gynecomastia: a rare etiology

Vicente Nuno , Barros Luisa , Saraiva Joana , Moreno Carolina , Guelho Daniela , Cardoso Luis , Carrilho Francisco

Introduction: Gynecomastia is a frequent reason for endocrinology consultation and its correct investigation is pivotal towards a precise diagnosis. We present a clinical case of a rare cause of gynecomastia.Case report: A 56-year-old male was referred to the hospital setting for an endocrinology consultation. He noticed increased breast size for a year, initially tender to palpation, and unquantified weight loss. Neither galactorrhea, nor any nipple dis...

ea0032p355 | Diabetes | ECE2013

Predictive value of HbA1c and glucose fluctuations in hypoglycemia risk in patients with type 1 diabetes

Guelho Daniela , Barros Luisa , Baptista Carla , Paiva Isabel , Gouveis Sofia , Saraiva Joana , Moreno Carolina , Carrilho Francisco

Introduction: Many patients with diabetes experience high variability in glucose concentrations which is associated with a risk of hypoglycemia. The aim of this was to compare the predictive value of HbA1C, mean interstitial glucose (MIG), and glucose variability (GV) in the risk of hypoglycemia in patients with type 1 diabetes (T1D).Methods: Continuous glucose monitoring, using CGMS system, was performed in 130 T1D patients with diabetes duration of 17....

ea0022p90 | Bone/Calcium | ECE2010

Primary hyperparathyroidism: retrospective evaluation

Santos Jacinta , Paiva Isabel , Barros Luisa , Vieira Alexandra , Alves Marcia , Gouveia Sofia , Carvalheiro Manuela

Introduction: Primary hyperparathyroidism (PHP) results from an excessive secretion of parathyroid hormone (PTH), typically leading to hypercalcaemia. This disorder is more common than previously expected, since it is frequently diagnosed in asymptomatic patients.Objectives: To characterize a group of patients with PHP, in what concerns to: age, clinical presentation, biochemical and imaging evaluation, treatment and evolution.Pati...

ea0020p1 | Adrenal | ECE2009

Hematoma: unusual presentation of adrenal masses

Vieira Alexandra , Baptista Carla , Paiva Isabel , Barros Luisa , Santos Jacinta , Martinho Mariana , Carrilho Francisco , Carvalheiro Manuela

Introduction: Adrenal hematomas are very rare entities. They occur often associated with: trauma, anticoagulation, coagulopathy, septicemia, pregnancy complications or tumors. When none of these predisposing factors is present, diagnosis and treatment can become a real challenge.Case report: A 19-years-old woman presented with complaints of asteny, loss of appetite, loss of 10 kg in a month, and pain in right lumbar and abdominal regions. No other compla...

ea0020p333 | Diabetes and Cardiovascular | ECE2009

Characterization of a young population of type 1 diabetics

Vieira Alexandra , Fagulha Ana , Barros Luisa , Figueiredo Julia , Santos Jacinta , Martinho Mariana , Carrilho Francisco , Carvalheiro Manuela

Introduction: Type 1 diabetes is one the most common chronic diseases found in children and youngsters.Objectives: Characterization of a sample of young type 1 diabetic patients, treated with multiple daily injections of insulin.Patients and methods: Analysis of patients files with ages between 11 and 26 years observed on diabetology consultation during the first semester of 2008, with diagnosis of diabetes for at least 6 months. P...

ea0020p390 | Diabetes and Cardiovascular | ECE2009

Prevalence of cardiovascular risk polymorphisms and its association with microvascular complications in an adolescent type 1 diabetes population

Melo Miguel , Fagulha Ana , Barros Luisa , Santos Jacinta , Vieira Alexandra , Carvalheiro Manuela

Objectives: To determine the prevalence of several polymorphisms associated with increased cardiovascular risk in a group of adolescents with T1DM. To study the possible association of some polymorphisms with the occurrence of microvascular complications.Methods: Patients were randomly selected from our outpatient clinic. The following polymorphisms were studied:: ACE Ins/Del, Apo B R3500Q, Apo E2, 3, 4, MTHFR C677T and A1298C, PAI 4G/5G, ITGB3 PL(A1)/(A...