Endocrine Abstracts

Introduction: In this study, we aimed to examine the weight alterations after the medical treatment and compare the effects of medical treatment in obese patients who applied to Endocrinology Policlinic.Material and method: We examined the patients who were diagnosed as obesity and initiated medical treatment at Endocrinology and Metabolism Diseases Policlinic in Inonu University Medical Faculty between Agust 2005–May 2008. Patients were divided int...

Introduction: Long term control of glucotoxicity has been shown to increase the secretion of insulin and C-peptide (Cp) from beta cells. However, there is limited data concerning the effect of short term glycemic control and reversal of glucotoxicity on basal Cp. We aimed to investigate the change in serum Cp levels after short term glycemic control in patients with uncontrolled type 2 diabetes mellitus (DM).Materials and methods: A total of 123 patients...

The most frequent pathology of primary hyperparathyroidism presented with the findings of hypercalcemia is parathyroid adenoma. Some patients having the signs of primary hyperparathyroidism may have intrathyroidal parathyroid adenoma and it may be overlooked. We present a case of intrathyroidal parathyroid adenoma presented with bone pain.47-year-old female patient referred to our clinics with bone pain and she had no pruritus, dry mouth, dyspepsia, abdo...

Introduction: Incretin based therapeutics have commonly been used in the last years for the management of patients with type 2 diabetes mellitus (DM). Linagliptin is a member of “dipeptidyl peptidase 4” (DPP-4) inhibitors and often preferred owing to some advantages over the others. We present a diabetic case developing skin findings after the initiation of linagliptin.Case: 66 year-old woman with a history of type 2 DM for 10 years was admitte...

Introduction: Most of the human studies suggested an association between obesity and low 25(OH)D3 0levels. It has been proposed that co-existence of vitamin D deficiency may have a role in the development of IR in obesity. We aimed to reveal whether any association was present between IR and 25(OH)D3.Materials-methods: 223 obese patients referred to our clinics were evaluated for the study. 24 patients with known diabetes mellitus were excluded. Finally,...

Introduction: Few studies have investigated the effect of gastric bypass surgery on lipid profile in obese patients with type 2 diabetes mellitus. We aimed to evaluate changes in lipid profile in obese diabetic patients undergoing Roux-en-Y gastric bypass (RYGB) surgery.Method: We retrospectively analysed 71 obese type 2 diabetic patients (46 women, 25 men) who underwent RYGB surgery. Weight, body mass index (BMI), total cholesterol (TC), high-density-li...

Introduction: It has been shown that type 2 diabetes mellitus (T2DM) could affect bone metabolism through several mechanism and it may increases risk for osteoporosis. Glucose lowering therapies including metformin has also been reported to may effect on bone turnover. This study aimed to evaluate the effects of metformin therapy on bone resorption and formation markers in newly diagnosed patients with T2DM.Method/design: Study population consisted of 37...

Introduction: Both endothelial dysfunction and albuminuria have been shown to be related to cardiovascular risk. We aimed to investigate relations between endothelial dysfunction, albuminuria and frequency of the microvascular complication in type 2 diabetic patients.Method: Forty type 2 diabetic patients (24 microalbuminuria and 16 macroalbuminuria) with a mean age of 57.2±10.8 years and 25 healthy control subjects with a mean age of 54.1±9.6 ...

Objective: The number of studies that investigate thyroid functions in obese patients is limited, and little known about the effect of co-existence of type 2 diabetes mellitus on thyroid functions. In our study, we aimed to evaluate the spectrum of thyroid function in the both diabetic and non-diabetic obese patients.Materials-Methods: 145 obese patients who were admitted to our department of endocrinology and metabolism, between June 2014 and December 2...

Background/purpose: The combination of DM and HT accelerates vascular complications and increases the risk of mortality and morbidity. Hypertension is seen in half of diabetic patients. HT can be detected in approximately 40% of newly diagnosed diabetic patients. DM frequency increased 2.5 times in hypertensive patients. The association of HT and DM is due to the common mechanism responsible for the pathogenesis of both diseases. There is a limited number of studies investigat...