Endocrine Abstracts

Introduction: Medullary thyroid carcinoma (MTC) is a relatively uncommon tumour of the thyroid as compared with papillary thyroid carcinoma (PTC). Concurrent of medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) in a single patient is a rare.Case: Forty-nine year-old male patient was referred to endocrinology for multinodular goiter evaluation. He had no palpable nodules. There was no apparent family history of endocrine disorders or...

Introduction: Hoffman’s syndrome is a rare form of hypothyroid myopathy characterised with muscle hypertrophy, stiffness and wakefulness.Case report: A 43-years-old woman admitted to our hospital with a complaint of fatigue and progressive muscular weakness with cramps and myalgia started 3 months before.Thyroid gland examination was normal. On neurological examination she had proximal and lower limb muscle weakness(3/4) and hyporeflexia. Her calf m...

Pitüitary ACTH deficiency is one cause of secondary adrenal insufficiency. Genetic factors, autoimmunity, infiltrative disease, cranial trauma can cause ACTH deficiency. Hyperpigmented skin lesions are expected in primary adrenal insufficiency while they are very rare in secondary adrenal insufficiency. Striae are characterized by linear smooth bands of atrophic appearing skin. They are mostly associated with obesity, pregnancy, hypercortisolism/Cushing syndrome. Striae a...

Introduction: Autoimmune thyroiditis (AIT), also called Hashimoto thyroiditis or chronic lymphocytic thyroiditis is characterized by destruction of the thyroid gland involving apoptosis of thyroid epithelial cells. It usually presents as euthyroidism or subclinically hypothyroidism, rarely as overt hypothyroidism. The cause of Hashimoto’s thyroiditis is thought to be a combination of genetic susceptibility and environmental factors. Bisphenol A (BPA), an endocrine-disrupt...

Introduction: Pituitary apoplexy is a relatively rare clinical emergency in endocrinology. It results from hemorrhage or infarction in the pituitary gland. This clinical state is characterized headache, vomiting, visual defects, and signs of meningeal irritability.Case: 22-years-old woman was referred to hospital because of predicted haemorrhagic or cystic pituitary adenom in magnetic resonance imaging (MRI). She was married but not a child. She had mens...

Introduction: Mammary duct ectasia (MDE) is an inflammatory breast disease characterised by dilation of major ducts and periductal inflammation. MDE occurs commonly in women undergoing menopause. The etiology has not been well defined but previous studies described an association between high prolactin and MDE.Case Report: A 42-year-old female was admitted to our hospital with complaints of galactorrhea, amenorrhea, mammary gland tenderness and breast di...

Introduction: Thyroid dysfunctions and autoimmunity may concur in the pathogenesis of hemostasis abnormalities. Hashimoto’s thyroiditis (HT) is a frequently chronic autoimmune disease in thyroid gland. The aim of our study were to comparison the hemostatic parameters in patients with HT and control subjects.Method: A total of 52 women were evaluated. Age, TSH, free T3, free T4, anti M, anti Tg, TAFI, TFPI, PAI-1, tPA, PF-4, fib...

A 44-year-old man with 6 months history of headache, fatique, depressive mood, anorexia, impotence, decreased libido, poliuria and polidypsia. The results of the physical examination were normal, except the patient had noduler guatr. Baseline hormonal investigations and dinamic tests showed panhypopituitarism and partial central diabetes insipidus. Magnetic resonance imaging (MRI) of the pituitary gland showed enlarged pituitary gland and a marked thickening (4.5 mm) of the in...

Aim: In our study, in regard with the women cases of obesity, we have aimed at determining the correlation that existed among the anemia markers, insulin resistance (IR) and fact of Metabolic syndrome (MetS).Method: We have conducted our assessment 67 women who had resorted to our clinic due to their obesity complaints and were in the premenopausal and mean age 36.7±8.8 years. We have put forward the demographic data and measured the biochemical (fa...

Aim: Hypoadiponectinemia is known to be associated with insulin resistance, diabetes and obesity. Since gestational diabetes is together with increased body mass index (BMI) and decreased insulin sensitivity, the evaluation of adiponectin levels in these patients is interesting. We investigated the relationship between adiponectin and glucose tolerance during pregnancy and after delivery.Materials and methods: We evaluated plasma adiponectin levels, insu...