Endocrine Abstracts

Background and aim: Serum Cystatin C has been shown to be associated with the progression to prediabetes and type 2 diabetes mellitus. High cystatin levels were also found to be associated with body mass index. The aim of this study was to evaluate cystatin C levels in diabetic and prediabetic patients ant its association with anthropometric measurements and insulin resistance.Methods: Twenty four patients with diabetes, 17 patients with prediabetes and ...

Background and aims: This study was done to predict renal impairment in type 2 diabetic patients with normo or microalbuminuria by detection of serum cystatin C, serum and urinary TGF-β levels.Material and methods: Seventy-eight patients were categorized into four groups depending on urinary albumin excretion and eGFR: eGFR <60 ml/min per 1.73 m2 with normoalbuminuria in group 1; eGFR was <60 or >60 ml/min per 1.73 m2</su...

Introduction: Green tea consumption has been reported to be associated with weight loss although the results of the studies are inconclusive and potential underlying mechanism is not yet clear. We aimed to evaluate the effect of green tea extract on weight loss, body composition and resting energy expenditure in obesity.Methods: Twenty-nine obese patients (body mass index (BMI) >30 kg/m2) were included in the study. Weight, BMI, waist circ...

Background and aim: Subclinical hypothyrodism (SH) appears to be associated with mood and changes. The aims of this study were: i) to determine whether depression is more common in SH, and ii) to investigate the effects of L-thyroxine (LT4) therapy on depressive symptoms.Methods: 31 patients with SH and 36 age amd BMI matched healthy controls were included. Beck and Hamilton scales were used to evaluate depression...

Background: Subclinical hypothyroidism (SH) is an endocrine disorder defined by increased thyrotropin (TSH) levels associated with normal free thyroxine (fT4) and free triiodothyronine (fT3). Resistin is secreted from the adipose tissue and is reported to be associated with insulin resistance and/or inflammation. High-sensitive CRP (hs-CRP) is a reliable marker of inflammation. Data related to levels of resistin and hS-CRP in SH is limited.<p class="a...

It has been previously shown that adrenal adenomas are associated with a variety of metabolic disturbances like glucose intolerance and obesity. The aim of this study is to demonstrate the risk of non-alcoholic fatty liver disease development in subjects with adrenal incidentalomas.Among 302 subjects referred between 2001 and 2008 for the evaluation of incidentally discovered adrenal mass, 150 subjects with appropriate data were included. Computed tomogr...

Background: High association of concomitant thyroid and parathyroid disorders has been reported. The aim of this study was to determine the prevalence and characteristics of thyroid disorders associated with primary hyperparathyroidism (PHPT) in Turkey, a country with mild iodine deficinency.Material and method: We retrospectively reviewed the records of patients diagnosed with PHPT between 1980 and 2007 at our clinic and analyzed the data related to thy...

Prediction of amputation would aid clinicians in the management of the diabetic foot infections. We aimed to assess the predictability of baseline and early post-treatment levels of acute phase reactants on the outcome of patients with diabetic foot infections.In this study, we included patients with infected diabetic foot ulcers who were hospitalized in Dokuz Eylul University Hospital between January 2003 and January 2008, of which data were collected p...

Introduction: Reduced creatinine clearance is related to an increased risk of diabetic foot ulcer development. Wound healing has been reported to be worse in diabetic patients with impaired kidney functions than general diabetic population. This study aimed to investigate the effect of creatinine clearance on the short term outcome of neuropathic diabetic foot ulcers.Materials and methods: Data from 147 neuropathic diabetic foot ulcer episodes were inclu...

Objectives: Endothelial dysfunction contributes to the development of atherosclerosis in diabetic subjects. Endothelin-1 (ET-1) is an endothelium derived vasoconstrictor. It has been shown that ET-1 levels are increased in a variety of situations such as diabetes, hypertension and obesity. Transforming growth factor beta1 (TGF-β1) is an important cytokine for the development of renal injury in type 2 diabetic patients and associated with hyperglycemia and insulin resistan...