Endocrine Abstracts

We describe the case of a 76 year old woman who presented to her GP with a two month history of abdominal pain, tiredness and nocturnal sweating episodes. Her past medical history included Hypertension (on Amlodipine, Bisoprolol) and Hypothyroidism (on levothyroxine). Abdominal USS and CT scan revealed a left adnexal mass measuring 15 cm. Ca-125 and CEA were normal. During admission under the Gynae-oncologists for a laparotomy, she suffered recurrent severe symptomatic hypogly...

Background: There is a relationship between the indices of nutriture-BMI, waist circumference (WC), waist–hip ratio (WHR) and the development of glucose intolerance.Objectives: To determine the normative values of the indices of nutriture and the inter relationship between these indices in male and female residents of a Calabar, South East Nigeria.Methods: A sample comprising 1134 subjects (645 males and 489 females) represent...

Introduction: Obesity is a strong risk factor for incident chronic kidney disease (CKD). Furthermore, high body mass index (BMI) is consistently associated with low serum vitamin D in the general population. The aims of the present study were to i) compare vitamin D metabolite levels in overweight/obese versus normal weight individuals with normal to severely impaired renal function and ii) to assess the impact of 25(OH)D on the development of secondary hyperparathyroidism (SH...

Introduction: Vitamin D deficiency has been frequently observed in the elderly population. Improving vitamin D status may be an important modifiable risk factor to reduce fractures; however, adherence to daily supplementation is poor. We tested whether oral administration of an alcoholic solution of vitamin D3, 200 000 IU every 4 months in elderly could assure an optimal serum 25(OH)D concentration of 80–120 nmol/l.Method: We enrolled 50 ...

Papillary thyroid carcinoma is a slow growing tumor and is reputed to have an excellent prognosis. In 10–20% of cases, the presence of lymph node metastases led to diagnosis.Objective: To present a patient with enlarged lateral cervical masses, present for 10 years, that proved to be lymph nodes with metastatic thyroid papillary carcinoma.Case report: We report a case of an 26-year-old female patient with 10 years evolution of...

Introduction: Current guidelines emphasize the important role of Continuous Glucose Monitoring (CGM) for type 1 diabetes mellitus (T1DM) management. The aim of the GlucoseML study is the development of a mobile health system for T1DM self-management based on CGM data, physical activity, food intake and insulin dosage. We herein present the development and evaluation of a univariate Autoregressive Moving Average (ARMA) prediction model of interstitial glucose concentration for ...

Introduction: Hyperparathyroidism-Jaw Tumor (HPT-JT) syndrome is a rare genetic disorder bearing a germline and a somatic CDC73 mutation. The features of HPT-JT are clinically difficult to ascertain because the parathyroid disease, ossifying fibroma in the jaw and other abnormalities, often occurs asynchronously and may be diagnosed and treated separately. The association of jaw ossifying fibroma with primary hyperparathyroidism (PHPT) is typical of HPT-JT.<p class="abstex...

Background: Amyloidosis is defined as the accumulation of amorphous, proteinaceous material in different parts of the body. It can be primary or secondary, having decreased the incidence of this last one due to the current therapeutic landscape of infectious and autoimmune diseases. This material can be deposited in the thyroid gland resulting in an enlargement known as Amyloid goiter. Although amyloid infiltration in thyroid is common, the occurrence of clinically enlarged th...

Background: Retroperitoneal Schwannomas are rare and generally benign tumors originating from the neural sheath. In particular, juxta-adrenal schwannomas may be misdiagnosed as adrenal tumors due to their location and radiological characteristics.Case Presentation: A 40-year-old female patient referred to our outpatient clinic owing to a left suprarenal mass of 35 mm incidentally discovered in an enhanced CT. She was asymptomatic and the clinical examina...

Objectives: Triiodothyronine (LT3) administration for 48hours in patients undergone primary angioplasty showed favourable effects on cardiac function and remodelling early after myocardial infarction (Thy-Repair, EudraCT 2016-000631-40, Thyroid 2022 Jun;32(6):714-724). The present study investigated whether this beneficial effect was dependent on the severity of infarct size. The extent of infarct size is one of the main determinants of morbidity and mortality after myocardial...