Endocrine Abstracts

CaseMale, 44 y.o., with rigth maxillary tumor of progressive growth for 1 year with local and low back pain. Imaging exams: CT/MRI skull and face: right axial expansive lesion (62×52×46 mm), heterogeneous, multiloculated with bulging of the right orbit inferomedial wall, with a neoplastic aspect. CT pelvis: bone lesions with soft tissue densities in pelvis, heterogeneous L4, with height reduction. Biopsy of the lesion suggesting a brown tumor. ...

This communication tests the hypothesis that iodine (I2) gas or iodine oxides released from seaweeds previously shown to enhance atmospheric iodine adjacent to seaweed hotspots, may through being inspired by respiration, supply a significant fraction of daily iodine requirements. This could assume importance in a country such as Ireland where iodised salt availability is <5%. Iodine intake was assessed by measuring urinary iodine (UI) excretion using a dry ashing technique...

Case report: 21-year-old female patient visited the emergency department with repeated attacks of vomiting accompanied with continuous non radiating epigastric pain diagnosed as acute pancreatitis. She had three plasmapheresis sessions. She gave history of recurrent similar attacks for the last 5 years with frequent hospitalization she is known diabetic since the age of 15.Hypertensive for 1 year. Menarche at age of 14 with only one cycle. Upon admission, the patient was alert...

A 64-year-old Algerian woman was transferred to our institution with a pituitary tumor causing severe visual impairment. Magnetic resonance imaging (MRI) showed a T1-isointense, T2-hyperintense sellar mass measuring 48×35×30 mm, with homogenous enhancement after gadolinium injection (Figure 1). This mass extended to the suprasellar region, compressing the optic chiasma, and to both cavernous sinus, completely surrounding and narrowing carotid arteries. Ophthalmologic...

Background: Vitamin D deficiency is common in elderly nursing home residents. It has been associated with low bone mineral density, muscle weakness, increased body sway and falls. Evidence indicates that supplementation of vitamin D in these individuals helps to improve locomotor function and general health.Patients and methods: We evaluated, in a 12 months interval, the effects of vitamin D supplementation on grip strength in 45 nursing home residents (...

Glucocorticoid receptor (GR) is a hormone-dependent nuclear transcription factor that modulates the expression of genes involved in development, inflammation, and metabolism. In addition, as GR is a key factor in several steroid dependent cancers steroid hormones are extensively used in the treatment of cancers such as leukemia. The transcriptional activity of GR is cell type specific and its magnitude and target selectivity depend on multiple factors including posttranslation...

Introduction: Extrathyroidal unique laterocervical masses are infrequent, and their etiological diagnosis is difficult. Since clinical and imagistic features cannot distinguish between different ethiologies, morphological data are mandatory in order to establish a precise therapeutic strategy. Therefore the initial treatment is surgery, followed by an adequate therapeutical scheme. We would like to report our experience treating this pathology.Patients a...

Background & aims: Impaired glucose tolerance and diabetes as well as cardiac dysfunction are known complications in homozygous beta-thalassemic transfused patients due to iron overload. We aimed to study pancreatic alpha and beta-cell function in regularly transfused patients with homozygous beta-thalassemia and to investigate if cardiac dysfunction may correlate with the development of impaired glucose metabolism.Methods: An oral glucose tolerance ...

Introduction: Paraneoplastic Cushing’s syndrome is attributed to ectopic ACTH release from a non-pituitary tumor. The lung is frequently the primary site of the underlying neoplasm but sometimes, in cases of advanced metastatic disease, determining the origin may be challenging.Case presentation: A70-year-old man was reffered to our centre for generalised bone pain, lethargy, and important weight loss in the last six months. Before admission, a cont...

Background: Intravenous bisphosphonates treatment brings real benefits to patients with bone metastases. Unfortunately, this treatment sometimes has a difficult to treat complication, often disabling for the patients – the osteonecrosis of the jaws. A new approach in the management of this complication is the use of platelet rich plasma (PRP).Patients and methods: Five patients aged between 62 and 72 years old (three men and two women) were included...