Endocrine Abstracts

Background: TSH-suppressive therapy is widely used in treatment of thyroid differentiated carcinoma. A common consequence of therapy is subclinical hyperthyroidism which may cause dysfunction of cardiovascular system, metabolism and reduction of bone mass1. Thyroid hormones are also involved in regulation of brain function2. Therefore, it is not surprising that thyroid dysfunctions are associated with frequent comorbid cognitive dysfunctions and depressio...

Piper betuloids is a creeper grown wildly in the tropical forests of the north east part of India. The ethnic people of this region, especially in Arunachal Pradesh use the secondary roots of this creeper for fertility control in women. The traditional preparation has been reported to be use orally during post coital period.Objectives: The anti-reproductive property of the secondary aerial roots has been tested on female albino rats during early g...

Introduction: Struma ovarii is often initially diagnosed as a suspected ovarian malignancy due to atypical characteristics on the imaging and hyperthyroidism is only seen in about 8% of presentation making thyroid function test (TFT) an unreliable test to suspect it pre-operatively. There are few case reports on its varied structural and functional characteristics in the literature. However, there are no reports of the influence of an intrinsic thyroid disease...

Background: Osteolytic metastases of the bone occur in several malignant tumors. Beside osseous metastases, endocrine diseases like primary hyperparathyroidism can mimic osteolytic metastases.Case report: A 53-year-old woman was sent to the hospital by an oral surgeon with a worsening of her general condition, fatigue, a painful tumor of the mandible, diffuse bone pain and the diagnosis of a suspected metastasized malignancy. Laboratory testing showed a ...

Objective: Digital pathology is the process of scanning conventional slides and then digitally stitching consecutive images into digital slides that can be viewed, managed, and analyzed on a computer monitor. In this study, we evaluated the area of metastatic foci in cervical lymph node (LN) metastasis in application of digital pathology and prognostic implication for predicting structural recurrence in patients with papillary thyroid cancer (PTC).Method...

Introduction: Langerhans cell histiocytosis (LCH) is a neoplastic histiocytic disorder that characterized by proliferation of abnormal Langerhans cells. The most typical organs affected by LCH are the skin and bones, though it can also affect the pituitary gland, central nervous system, liver, spleen, lungs, and other organs.Case 1: 36 year old man presented with polyuria, polydipsia and right hip pain lasting about 4 months. The pain increased in the la...

Introduction: Parents/carers of children with adrenal insufficiency routinely receive training on the provision of emergency hydrocortisone. This service improvement project aims to assess patient and parent knowledge on their sick day rules, in NHS Tayside, with a view to improving the delivery of this information.Methods: A 24 item postal questionnaire was constructed and distributed to parents of children with adrenal insufficiency. This included 11 s...

Introduction: Santé publique France develops a national epidemiological monitoring program to study health indicators related to endocrine disruptor exposure. Based on the weight of evidence, cryptorchidism was selected for this purpose. In this study, we aimed to analyze temporal, spatial and spatio-temporal trends of cryptorchidism during the period 2002–2014 in France, and explore and/or generate environmental hypotheses.Methods: We built a...

Background: Primary aldosteronism is identified in approximately 10% of hypertensive all-comers. Adrenal vein sampling (AVS) allows localization of aldosterone production, identifying cases where unilateral adrenalectomy can be curative. Unfortunately, AVS is technically challenging.Methods: Data from AVS procedures performed in BC were extracted from the SunQuest laboratory information system in Vancouver Coastal Health. Cortisol and aldosterone levels ...

Objectives: To determine the mean and normative values of anthropometry among the inhabitants of a coastal Nigerian city.Methods: A cross sectional survey comprising 1134 subjects (645 males and 489 females) representative of the entire population of Calabar metropolis aged 15–79 was studied. A multistage sampling method was applied to select the subjects. Using a modification of WHO STEPS instrument the information obtained included anthropometric ...