Endocrine Abstracts

Background: Obesity is a major public health issue frequently associated with increased complication rates after elective general surgery. Previous reports on complications after thyroid surgery in obese patients were performed on selected cohorts. In this study, we sought to explore the relationship between Body Mass Index (BMI) and postoperative morbidity after thyroid surgery in a large cohort of consecutive patients.Materials and Methods: A single-ce...

Introduction: Gestational diabetes (GD) is a known risk factor for delivery, fetal and perinatal complications. Fetal male sex is known to be associated with worse perinatal outcomes, such as macrosomia, neonatal hypoglycemia, low Apgar scores, birth defects and mortality. However, studies evaluating the impact of fetal sex on perinatal outcomes in women with GD are scarce. Objectives: We aimed to study whether male newborn sex is associated with neonata...

Introduction: Women with gestational diabetes (GD) have an increased risk of developing future type 2 diabetes mellitus (T2DM). A reclassification oral glucose tolerance test (OGTT) is currently recomended in the postpartum period. However, most studies report a compliance rate below 50% and as low as 23%.Objectives: We aimed to study predictors of missing postpartum OGTT in women with GD.Materials and Methods: Retrospecti...

Introduction: There are several known risk factors for gestational diabetes mellitus (GDM), a condition associated with worse pregnancy outcomes. Once GDM is established, the association between the presence of GDM risk factors and pregnancy outcomes is less well-known. We studied the association between the number of GDM risk factors and pregnancy outcomes in a population of women with GDM.Methods: Retrospective study of the Portuguese multicentre GDM r...

Introduction: Positive radiotracer uptake by the thyroid gland can occur in PET-CT. It’s meaning has led to conflicting results mainly resulting from small studies.Objective: We aim to present a large single institution consecutive case series.Material and methods: Observational, descriptive and retrospective study of the PET-CT scans performed between the years 2000–2017. We searched the word thyroid in the computer imag...

Introduction: Familial partial lipodystrophy (FPL) is an autosomal dominant disease characterized by selective loss of subcutaneous fat from the extremities and gluteal region, with lipohypertrophy of the face, neck and trunk. It is usually tightly linked with severe metabolic complications. FPL type 3 results from peroxisome proliferator-activated receptor gamma (PPARG) mutations.Case presentations: Fifty three-year-old woman, referred to endocrinology ...

Introduction: Bariatric surgery improves lipid profile. A still unanswered question is whether this improvement is merely weight dependent or also results from factors inherent to specificities of the bariatric procedure itself. We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in patients matched for initial weight and for weight loss.Methods: We retrospectively analysed patients subm...

Introduction: Amiodarone-induced thyrotoxicosis (AIT) in patients with congenital heart disease (CHD) has an estimated cumulative incidence of 13–21%, and prompt reversal to euthyroidism is crucial in these patients. We present a case of refractory AIT in a patient with CHD who was treated with thyroid arterial embolization (TAE).Clinical case: A 34-year-old male with complex cyanotic CHD (great vessels transposition, interventricular communication...

Most differential diagnoses of unilateral adrenal lesions include non-functional adenoma, adrenocortical carcinoma or pheochromocytoma. Primary adrenal lymphoma(PAL) is an extremely uncommon type of primary extranodal non-Hodgkin’s lymphoma(<1%). Most cases are bilateral (~75%), being unilateral PAL scarcely reported. The apparent unilateral involvement of this entity at presentation, in the CT scan/MRI may difficult the diagnosis, delaying the start of chemotherapy. ...

Introduction: Familial neurohypophyseal diabetes insipidus (FNDI) is a rare form of central diabetes insipidus (CDI) characterized by childhood-onset progressive polydipsia and polyuria due to mutations in the arginine vasopressin-neurophysin II (AVP-NPII) gene.Case description: Two male siblings were referred at 1 month of age to exclude CDI owing to a family history of CDI in the father and paternal grandfather. The proband was the fa...