Searchable abstracts of presentations at key conferences in endocrinology

ea0040lb11 | New insights on adrenocortical tumors OMICs | ESEBEC2016

L11 – Biography

Jérôme Bertherat is professor of Endocrinology at Paris Descartes University, Chief of the Endocrinology Department of Cochin Hospital, head of the National Center for Rare Adrenal Diseases and of the research team ‘Genomics and Signaling of Endocrine TumorsÂ’ in the Cochin Institute (INSERM U1016 & CNRS UMR8104), Paris, France. He serves as the coordinator of the French National Network for Rar...

ea0013s3biog | Society for Endocrinology Asia and Oceania Medal Lecture | SFEBES2007

Society for Endocrinology Asia and Oceania Medal Lecture

Morohashi K

K Morohashi, National Institute for Basic Biology, Okazaki, Japan. AbstractKen Morohashi received a PhD from the Department of Biology, Graduate School of Science, Kyushu University in 1986. After studying regulation of steroidogenic genes with Prof. Omura, he was invited as a professor of the Division of Sex Differentiation by the National Institute for Basic Biology, National Institutes for Natural Sciences in 1996. ...

ea0003s2biog | Society for Endocrinology Transatlantic Medal Lecture | BES2002

Society for Endocrinology Transatlantic Medal Lecture

Challis JRG

John RG Challis, CIHR Institute of Human Development, University of Toronto, Canada AbstractJohn Challis is currently the Scientific Director of the Canadian Institutes for Health Research (CIHR) Institute of Human Development, Child and Youth Health. He is also Professor of the Departments of Physiology and Obstetrics and Gynaecology at the University of Toronto, Affiliate Scientist of the Samuel Lunenfeld Research In...

ea0096p25 | Section | UKINETS2023

Sequencing of treatment in G1-2 pancreatic neuroendocrine tumour - a case study

J Shi , D Sarker , J Mencel , R Srirajaskanathan , S Brown , D Clement , J Ramage , S Dolly

Herein, we present the case of a 48yo Caucasian male diagnosed with a well differentiated (WD) pancreatic NET. At primary resection in 2014 pathological staging was pT3N1M0 R0 with Ki67 4%. 5 years later he developed recurrence in local lymph nodes and started on lanreotide followed by IRE on subsequent progression. In 2020, there was strongly DPET-avid metastases in mesenteric nodes and liver, so he was enrolled onto the COMPETE trial1. There was sequential progressive diseas...

ea0077p163 | Bone and Calcium | SFEBES2021

Symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy

Beck Adele , Reddy Venkat , Sulkin Tom , Browne Duncan

Primary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. Its prevalence in pregnancy is reported to be between 0.15% and 1.4%[i][ii]. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and foetus (foetal death, congenital malformations, neonatal severe hypocalcaemia induced tetany)[iii][iv]. However, there is a lack of clear guidance on management of primary hyperparathyroidism in pregnancy. We describe the ...

ea0081ep74 | Adrenal and Cardiovascular Endocrinology | ECE2022

Magnetic iron oxide nanoparticles for the delivery of thermal therapy for the treatment of primary aldosteronism

Sorushanova Anna , Donlon Padraig , Covarrubias-Zambrano Obdulia , Covarrubias Jose , Varghese Sunitha , Owens Peter , O'Halloran Martin , Prakash Punit , Bossmann Stefan , Dennedy Michael Conall

To minimise damage to surrounding tissues, targeted delivery of therapeutics to the tumour is highly desirable, and the development of nanotechnology has shown promising results. Magnetic iron oxide nanoparticles (MIONPs) have been gaining traction over the years for applications such as drug delivery, molecular imaging and delivering hyperthermia for treatment of various cancers (1). MIONPs have great therapeutic potential as they can be produced in various sizes and shapes, ...

ea0090ep364 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Erectile dysfunction: An early warning sign of urinary disorders in men suffering from diabetes

Haj Kacem Akid Faten , Missaoui Abdel Mouhaymen , Soomauroo Siddiqa , Trimeche Oumeyma , Majdoub Nabila Rekik , Salah Dhoha Ben , Hedi Mohamed Abid

Objective: To determine the prevalence and analyze the predictive value of erectile dysfunction (ED) in the occurrence of fictional disorders (MD) in men with diabetes mellitus (DM).Patients and Methods: Cross-sectional study of 90 men presenting with DM. A comparative analysis was performed between two subgroups: G1 (n=75) with MD vs G2 (n=15) without MD.Results: G1 patients were older than G2 (59.7±10.3 vs 58...

ea0070aep764 | Pituitary and Neuroendocrinology | ECE2020

Combined pitutitary hormone deficiency in a patient with charge syndrome

Nikitas Skarakis Spyridon , Karachaliou Feneli , Mitrogiorgou Marina , Simatou Aristofania , Bountouvi Evangelia , Papaevangelou Vassiliki

Background: CHARGE is an autosomal-dominant syndrome which includes a variable combination of ocular coloboma, heart defects, atresia of the choanae, retardation of growth and development, and genitourinary and ear abnormalities CHARGE syndrome has rarely been associated with anterior pituitary dysfunction and with structural abnormalities of the pituitary gland only twice. We report the case of a child with CHARGE association and congenital hypopituitarism due to structural a...

ea0019s7biog | Clinical Endocrinology Trust Visiting Professor Lecture | SFEBES2009

Clinical Endocrinology Trust Visiting Professor Lecture

Molitch Mark E

Mark E Molitch, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA AbstractMark E. Molitch, MD, is Professor of Medicine and a Member of the Division of Endocrinology, Metabolism and Molecular Medicine at Northwestern University Feinberg School of Medicine, in Chicago, Illinois. Prior to joining the faculty at Northwestern in 1984, Dr. Molitch was an Associate Professor at Tufts University School of...

ea0008p57 | Growth and development | SFE2004

The influence of environmental temperature and hormonal manipulation on adipose tissue (AT) uncoupling protein (UCP) 3 expression in neonatal pigs

Elmes M , Litten JC , Perkins KS , Laws J , Symonds ME , Mostyn A , Clarke L

It is well established that the reduced neonatal mortality in Meishan, compared to commercial piglets, is due to resistance to hypothermia and hypoglycaemia. Underlying factors responsible for the differences in survival may include the disparity in plasma tri-iodothyronine (T3) concentrations and UCP expression (Mostyn et al (2004) Journal of Endocrinology, in press). ZD7114 (ZD), a synthetic beta3-adrenoceptor agonist, has been shown to improve thermogenesis in la...