Searchable abstracts of presentations at key conferences in endocrinology

ea0065p322 | Neuroendocrinology | SFEBES2019

Pituitary incidentalomas: are we getting it right?

Paterson Alistair , Srinivasan Bala , DeSilva Akila , Overton Daniel

Background: With advances in radiological technology, the detection of incidentally discovered pituitary abnormalities is increasing, 90% being secondary to pituitary adenomas. Patient morbidity increases when these lesions are large enough to cause hormone insufficiency or visual field defects, highlighting the importance of appropriate management.Aim: To evaluate management of patients with pituitary incidentaloma in accordance with national guidelines...

ea0065p345 | Reproductive Endocrinology and Biology | SFEBES2019

Placental expression of progesterone receptor is down regulated in fructose-induced diabetic rats

Ogunsola Oluseyi Abimbola , Iranloye Bolanle , Adegoke Feyiade

Maternal diabetes is known to impair placental function; however, its effect on placental expression of progesterone and oestrogen receptors has not been well documented. Fructose has been used to induce insulin resistance in animal models (Suga et al., 2000). The study aimed to assess maternal serum levels of progesterone, oestriol, oestradiol; placental morphology and its expression of progesterone and oestrogens receptors in fructose-induced diabetic rats. Twelve f...

ea0063p594 | Diabetes, Obesity and Metabolism 2 | ECE2019

Relationship between lipid profile and uricemia in diabetic type 2

Mahroug Ikram , Bouali Houda , Latrech Hanane

Introduction: Hyperuricemia is associated with an increase in cardiovascular risk and complications of type 2 diabetes (1). The aim of this study is to establish a possible link between lipid profile and hyperuricemia.Method: A total of 321 patients with type 2 diabetes were included in our study. Clinical and par clinical data were collected from patientsÂ’ medical records. The lipid profile includes low density lipoprotein (LDL), high density lipop...

ea0049gh1biog | The Geoffrey Harris Prize Lecture | ECE2017

Geoffrey Harris Prize Winner

The prestigious Geoffrey Harris Prize is awarded to an established researcher in the field of neuroendocrinology and is the first of its kind in Europe. This years recipient is Professor Matthias Tschöp who will receive his prize and deliver his lecture as part of the ECE 2017 Opening Ceremony on Saturday 20 May 2017. Further information on the prize can be found at http://www.ese-hormones.org/prizes/.<...

ea0044p121 | Neoplasia, cancer and late effects | SFEBES2016

Psychosocial impact of multiple endocrine neoplasia disorders

Grey Joanna , Winter Kym

Multiple endocrine neoplasia (MEN) disorders are autosomal dominantly inherited syndromes characterised by multi-glandular adenomas/carcinomas. AMEND is a charity providing support and information resources to MEN patients. A recent anonymous online patient survey was conducted by AMEND into the psycho-social impact of the conditions. 219 patients participated (n101 MEN1, n60 MEN2a, n26 MEN2b, n32 other) with a mean age of 47.5 years. 57% felt that their condition had a negati...

ea0044p166 | Neuroendocrinology and pituitary | SFEBES2016

Corticosteroid-driven response of synaptic plasticity-associated targets are differentially regulated in the rodent brain: transcriptional actions of receptor modulators

Udeh-Momoh Chinedu , Spiga Francesca , Waite Eleanor , Thomson Fiona , Lightman Stafford

Actions of the stress hormone, glucocorticoid (GC), are essential for the modulation of implicated biological processes such as synaptic transmission. In disease paradigms that feature a hormone hyper-secretion phenotype (e.g. neurocognitive disorders), the normalcy of receptor signaling is compromised.The pro-cognate role of Glucocorticoid receptor (GR) inhibition via hormone analogues bearing anti-glucocorticoid properties is well described. A key exam...

ea0043oc60 | Translational and Preclinical Trend in Diabetes | WCTD2016

Glucose transporters and C peptide role in diabetes control a preclinical review of literature

Pham Thuy , Dao Marvin , Singh Mukunda

Background: C-peptide therapy ameliorates sensory nerve function in T1DM neuropathy. Prolonged GLUT-4 translocation and delayed counter regulation can induce hypoglycemia. GLUT-2 protein is the primary hepatic liver transporter related to hepatic glucose regulation it also plays a role on glucose sensing by pancreatic beta cells, via hepatoportal sensors controlling the autonomic nervous system and stimulates glucagon secretion.Objective: To discuss the ...

ea0041ep469 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

The differences in insulin doses and the risk of hypoglycemia in 2 distinct days in the Romania diabetes futsal team

Cosma Daniel-Tudor , Silaghi Alina Cristina , Silaghi Horatiu , Veresiu Ioan Andrei

In type 1 diabetes athletes, the proper adjustments of insulin doses and carbs intake are essential in order to avoid a hypoglycemic event that could affect the sport performances.The aim of the study was to assess the risk of hypoglycemia, the insulin and glycemic variability in 2 different days (with and without physical activity) in a group of nine players with type 1 diabetes, members of the Romania diabetes futsal team (twice European champion)....

ea0059pl5 | Clinical Endocrinology Trust Visiting Professor Lecture | SFEBES2018

SIAD; a modern approach to diagnosis and management

Thompson Chris

The initial report of the syndrome of Inappropriate Antidiuresis (SIAD) was published as recently as 1960 in the American Journal of Medicine. Schwartz and colleagues described an elegant series of physiological studies, in which two patients with hyponatraemia and lung carcinoma were shown to have an inability to excrete a water load, and who responded to water restriction with a rise in plasma sodium concentration. They termed this syndrome SIADH; in the 60 years since then,...

ea0059sk1.5 | Skills 1: Presentation skills | SFEBES2018

How do I respond to peer review?

Farquharson Colin

Having spent many months, if not years, obtaining and analysing your data you are ready to submit your manuscript to your preferred Journal. There is one step though that is often over-looked; responding to reviewerÂ’s comments i.e. the peer review process. This can be challenging to all but especially those who have not experienced the process before. There are however some golden rules, that if followed can make the process easier and result in your goal of gett...