Endocrine Abstracts

Introduction: Pregnancy in patients with pituitary pathology is a rare and delicate situation. However, risks for the mother and the foetus as well as the consequences of pregnancy on the history of pituitary adenoma require close monitoring.Goals: Illustrate through 5 observations the evolution of pituitary pathology during pregnancy.Observations: 1st patient: 41-year-old followed for somatotropic pituitary macro ...

Introduction: Metabolic disorders caused by acromegaly are responsible for three times the morbidity of the general populationStudy objectives: To analyze the different metabolic complications in acromegalic patients.Materiel and methods: This is a retrospective study of 62 cases of acromegaly followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2005 to December 2022. The data analysis was d...

Introduction: Acromegaly is an unusual disease in adolescence. Its diagnosis and management are a challenge in this population. Here we report 2 rare cases of acromegaly in this age group.Patients and Observations: Observation 1: This is a 17 year old patient admitted for acromegaly on pituitary microadenoma measuring 4*3mm who presents a symptomatology made of an accentuation of the growth rate, thin and long limbs, elongated hands and ...

Introduction: Prolactin adenomas are the most common pituitary adenomas. Although the pituitary increases in size and the prolactinoma increase gradually during normal pregnancy; prolactinomas do not contraindicate pregnancy but require strict monitoring.Goals: To study the impact of pregnancy on the development of prolactin pituitary adenomas.Materials and methods: Retrospective descriptive cohort study conducted in the endocrinol...

Introduction: Cushing’s disease (CD), a hypercorticism caused by an ACTH-secreting pituitary adenoma, was associated with a 5-year survival of only 50%. Although advances in management have significantly reduced mortality, the results of transsphenoidal surgery, the gold standard in the treatment of CD, vary from patient to patient.Objective: The aim of our study is to evaluate the results of transsphenoidal surgery in CD (evolution, complications) ...

Background: Non-functioning pituitary adenomas (NFAs) are slow growing tumours with reported 5-year recurrence rates following resection up to 51%. The time point that it is safe to stop surveillance imaging is not clearly defined.Aim: To clarify the time spectrum of recurrence in patients with NFAs offered solely surgery as primary treatment and to estimate the safe time to stop surveillance pituitary imaging.Methods: Case-note an...

Multiple meningiomas are rare benign tumors (1.5% of all meningiomas). They are either sporadic or associated with neurofibromatosis. Their long term morbidity is high due to the frequency of surgical procedures needed to overcome the absence of efficient adjuvant therapy. We present a cohort of patients in whom we strongly suspect cyproterone acetate to be responsible for the development and progression of multiple meningiomas.Patients and methods: We r...

IntroductionThe adrenal cortex is a rare malignant tumor at the expense of the adrenal gland, very aggressive because of its invasion, its metastatic potential and its five (5) year survival at 40% with a high risk of locoregional relapse.Case presentationWe report the case of a 17-year-old patient with a history of long-term corticosteroid therapy over 3 years and secondary amenorrhea for 2 years, who was ad...

IntroductionEpidermal growth factors accelerate healing in lesions of trophic disorders.MethodsThis is a prospective study carried out between February and June 2019 in the endocrinology and metabolic diseases department, involving 6 patients admitted for diabetic foot progressing for more than 3 months without healing after conventional treatment. Having received the injections of growth factors of the EGF t...

IntroductionType 2 diabetes has long been considered a disease of overweight adults. However, its incidence is increasing rapidly in children and adolescents along with that of overweight and obesity. The aim of this study was to assess the prevalence and clinical profile of type 2 diabetes in young subjects.Materials and methodsDescriptive prospective study from January 2019 to August 2020 including 30 diabe...