Endocrine Abstracts

Hypovitaminosis D is associated with an increased prevalence of diabetes mellitus type 2 (DMT2) and the metabolic syndrome. The purpose of this study was to examine the association between 25-hydroxy-vitamin D (25-OH-VitD) levels and adipocytokines and other indices of insulin resistance in a Saudi population with DMT2. One-hundred and fifty-five male and female Saudi adults aged 26–80 were randomly selected from the existing Biomarkers Screening in Riyadh Program (RIYADH...

We studied the association between RBP4 and various markers related to insulin resistance and diabetic complications as well as inflammatory markers in Saudi population suffering from type 2 diabetes and coronary heart disease. Patients with type 2 diabetes were divided into 3 groups according to the type of treatment and involvement of coronary artery disease. Serum TNF-α, insulin, CRP, resistin, leptin and adiponectin were analysed in all samples. RBP4 plasma levels inc...

Introduction: Glucocorticoid resistance syndrome is a rare disease, sporadic or familial, of autosomal dominant or recessive inheritance. It is a partial or complete inability of glucocorticoids to exert their effects on target tissues. Associated with compensatory increases in corticotropin and circulating cortisol with excessive secretion of adrenal androgens and mineralocorticoids.Observation: A 67-year-old patient, having recently discovered diabetes...

Introduction: Adolescent and young adult differentiated thyroid cancers are frequently under diagnosed forms. They would be characterized by their aggressiveness and the presence of particular histological forms. The aim of the study was to describe the characteristics of thyroid carcinoma in adolescents and young adults by analyzing the clinical, histological, therapeutic and evolutionary characteristics.Materials and methods: We conducted a retrospecti...

Introduction: Oncocytic thyroid carcinoma is rare. It is an aggressive tumor, with high nodal and distant metastatic potential.Purpose of the study: to describe the epidemiological, clinical and anatomopathological particularities of oncocytic carcinomas of the thyroid.Method: Descriptive retrospective study, including patients followed in thyroid carcinoma consultation at the Endocrinology Department of the CHU Ibn Rochd in Casabl...

Introduction: NIFTP (non invasive follicular neoplasm of the thyroid with papillary-like nuclear features, formerly noninvasive encapsulated follicular variant of papillary thyroid carcinoma) has been removed from the carcinoma category due to its indolent nature and its good prognosis. The purpose of our study was to identify preoperative ultrasound and cytological differences between NIFTP and papillary thyroid carcinoma (PTC).Materials and methods: re...

Introduction: Hematologic abnormalities are frequently observed during hyperthyroidism and are related to complex multifactorial pathogenic mechanisms that are still poorly understood and may affect the three hematopoietic lineages in isolation or in combination. These abnormalities are exceptionally revealing and are usually subclinical. For the endocrinologist, they raise the problem of the risk of their aggravation under the hematotoxic effect of synthetic antithyroid drugs...

Introduction: Refractory hypothyroidism is known as the persistence of clinical and biological signs of hypothyroidism after 6 weeks of treatment or therapeutic adjustment, despite a dose exceeding 1.9μg/Kg/d of Levothyroxine. Several etiologies may be incriminated.Observation: A 36-year-old patient, followed for Gougerot-sjogren syndrome, having benefited from a thyroidectomy in 2015 in a context of biological hyperthyroidism, on Levothyroxine (LT4...

Introduction: Ramadan, the holy month of fasting, is a stressful period that exposes to endocrine disturbances, which may decompensate some endocrinopathies or precipitate their revelation.Objectives: To evaluate the incidence of endocrine emergencies during the month of Ramadan, and thus the risk of endocrine decompensation related to fasting.Materials and methods: This is a prospective study conducted in the department of endocri...

Introduction: Ramadan fasting is associated with an increased risk of hypoglycemia in diabetics.Purpose of the study: To assess the prevalence of diabetic patients who are unable to break the fast in the event of hypoglycemia.Method: Descriptive prospective study, including diabetic patients followed in the Endocrinology department of the CHU Ibn Rochd in Casablanca from April to June 2021.Results: Our study ...