Endocrine Abstracts

Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common feature of type 2 diabetes mellitus (T2DM). Liver fibrosis has been associated with an increased risk of cardiovascular diseases (CVD).Aim: To investigate whether the fibrosis 4 index (FIB-4), a non-invasive marker of liver fibrosis, is associated with CVD or cancer in patients with T2DM.Methods: Two hundred and nine consecutive T2DM patients...

Objective: Kidney function is known to be interrelated with the aging process. On the other hand, a number of studies support a link between the menopausal transition and kidney function, either directly or indirectly, secondary to the effect of the alternating hormone environment or the effect of the accumulated cardiovascular risk factors, respectively. We aimed to evaluate the cross-sectional association between kidney function and sex hormones at the time of the menopausal...

Background: Both surgical and spontaneous menopause are associated with increased cardiovascular disease (CVD) risk. Recent evidence reported that clusters of menopausal symptoms are associated with accumulation of cardiometabolic risk factors. Climacteric symptoms are also known to be affected by lifestyle parameters, ethnicity, the geographical location as well as by the overall health status at the time of the menopausal transition.Aim: This study aim...

Background: While the association between cigarette smoking and type 2 diabetes is established, the impact of smoking on developing gestational diabetes mellitus (GDM) remains controversial.Aim: To investigate whether maternal cigarette smoking during pregnancy is a risk factor for developing GDM.Methods: MEDLINE, Scopus, CENTRAL and Google Scholar databases were searched from inception to December 2022 to identify eligible origina...

Objective: To evaluate the association between genetic background and the presence of oligo- or amenorrhea in a sample of adolescent girls diagnosed with anorexia nervosa compared with controls.Methods: A total of 40 adolescent girls diagnosed with anorexia nervosa aged 14–17 years, as well as 10 age-matched girls, were included in the study. We recorded anthropometric parameters and calculated body mass index (BMI) z-scores adjusted for age, as wel...

Background: Arterial stiffness is a well-established surrogate marker of vascular properties and arterial dysfunction in patients with type 2 diabetes mellitus (DM2). We aimed to investigate whether optimization of DM2 therapy with, additional to metformin, novel antiglycemic agents may improve arterial wall properties and achieve better glycemic control.Methods: We enrolled 99 consecutive patients (male gender=63.3%) receiving metformin for DM2 who did ...

Introduction: The aim of this study was to evaluate the association between a personal history of lactation and indices of subclinical atherosclerosis and arterial stiffness in postmenopausal women.Patients and methods: This cross-sectional study included 283 postmenopausal women. Sonographically assessed indices of vascular function [pulse wave velocity (PWV)] and vascular structure [intima-media thickness (IMT), atherosclerotic plaque presence] were te...

Introduction: A growing body of evidence is supporting a beneficial impact of breastfeeding on maternal metabolism and overall cardiovascular risk. The aim of this study was to evaluate the association between prolactin levels and metabolic parameters as well as indices of subclinical atherosclerosis, in a sample of premenopausal women with normal levels of prolactin.Patients and Methods: This cross-sectional study included a total of 64 non-lactating pr...

Introduction: The aim of this study was to investigate the incidence of hypertension and to identify potential risk factors in healthy, non-diabetic recently postmenopausal Greek women with normal renal function.Patients and methods: In this retrospective cohort study, we evaluated 141 recently postmenopausal women at baseline and annually thereafter (follow-up time: 1 to 8 years). Blood samples were obtained and ultrasound evaluations were performed at ...

Introduction: Ovarian senescence and fluctuating levels of sex hormones is associated with metabolic derangement and central obesity. The aim of this study was to explore the association between serum levels of sex hormones and metabolic health in non-obese postmenopausal women.Patients and methods: This cross-sectional study included a total of 457 non-obese postmenopausal (BMI <30 kg/m2) women, retrieved from the Menopause Clinic of Aret...