Endocrine Abstracts

Case report: 66 year old male with a neck growing mass performed an ultrasonography and fine-needle aspiration biopsy which was suspicious for papillary carcinoma. The patient was submitted to total thyroidectomy and central and left lateral compartments lymph node dissection. The histological report showed a follicular carcinoma of 9 cm, with multiple lymphovascular invasions and skeletal muscle invasion. There was a focally positive surgical margin and resected lymph nodes h...

Primary Aldosteronism (PA) is the most prevalent cause of secondary hypertension. The aim of this work was to characterize the diagnostic workup, treatment and follow-up of confirmed PA.The adrenal tumour study group of the Portuguese Society of Endocrinology undertook the first retrospective multicentre study of Portuguese PA patients. Data was gathered from nine Portuguese Endocrinology centres (three in the north, one in the centre and five in the sou...

Introduction: Pituitary macroincidentalomas are rare, being found in only 0.2%–0.3% of the patients that undergo imaging studies for an unrelated reason. The majority of them are non-functioning adenomas.Case Report: Woman, 77 years-old, with type 2 diabetes mellitus, hypertension and primary hypothyroidism. She was referred to Endocrinology due to a pituitary incidentaloma (18 mm of maximal diameter, with extension to the cavernous sinus and to the...

Introduction: New techniques such as etapification ecotomography (EE) have led to less invasive surgeries in Differentiated Thyroid Cancer (DTC). The trend in recent years has been to a reduction in the doses of radioiodine administered. Our hospital in 2013 incorporated these features to protocolize the administration of radioiodine depending on the characteristics of the tumour and the initial thyroglobulin levels, which may have had an impact in the response to treatment (R...

Introduction: The prediction of the risk of recurrence in differentiated thyroid cancer (dtc) in chile is different from ata. The use of the stimulated thyroglobulin (tg) post-surgery in the prediction of the risk is controversial. We present a cohort applying a new local protocol that includes the tg for supporting the discrimination of the patients for offer low doses or radio iodine.Objective: Asses if the local risk classification (lc) allow us to di...

Context: Loss-of-function of immunoglobulin superfamily 1 (IGSF1) causes an X-linked syndrome of central hypothyroidism, macroorchidism, and variable prolactin deficiency, GH deficiency in childhood, delayed pubertal testosterone rise, and/or obesity. The clinical features advert towards a pivotal role for IGSF1 in the pituitary gland, but detailed knowledge on pituitary hormone secretion in this syndrome is lacking.Objective: To study detailed ...

Introduction: Subclinical hypothyroidism appears to be related with an increased risk of cardiovascular disease. It was our objective to evaluate the relationship between autoimmune thyroiditis, subclinical hypothyroidism, and cardiovascular risk factors.Methods: We evaluated thyroid function tests, autoimmunity, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, ApoA1, ApoB, Lp(a), homocysteine, high sensibility CPR, folic acid, vitamin...

Thyroid storm (TS) is one extreme of a continuum beginning with thyrotoxicosis. It’s rarely caused by exogenous thyroid hormone intake (ETHI). Aggressive medical therapy is the cornerstone of treatment; nevertheless, it might not be sufficient. Plasmapheresis is an extracorporeal technique that can rapidly lower thyroid hormone levels. The aim of this study was to assess the efficacy of plasmapheresis in TS secondary to ETHI. We evaluated retrospectively all TS cases (Bur...

Primary hyperparathyroidism (PHPT) is frequently diagnosed as an incidental finding of hypercalcemia. Overt bone disease (osteitis fibrosa cystica or brown tumor), with history of pathologic fractures is a rare presentation.A 48-year-old woman was admitted in with pain in the right thigh after a trivial fall. She also complained of generalized weakness and lethargy over the last 2 years. Her medical history mention multiple bone fractures in the last 6 y...

Introduction: Postprandial hypoglucaemia with hyperinsulinism after laparoscopic gastric bypass is an uncommon complication with an estimated prevalence of 0.2%. Its treatment includes acarbose, diazoxide, somatostatin and GLP-1 analogues or calcium channel blockers in case a strict diet does not work.Case report: A 42-year-old woman with history of gastric bypass in 2005 due to severe obesity (preoperative weight 150 kg) attended our clinic 3 years afte...