Endocrine Abstracts

The aim of study: Is to assess the frequency of occurrence of vertebral fractures (VFx) and their relationship with hip geometric parameters in type 2 diabetes mellitus (T2DM) postmenopausal women.Materials and methods: We examined 94 T2DM women, age: 59.6(55.1–63.2)yrs., duration of DM: 7(4.5–11)yrs., duration of menopause 8.5(4–13)yrs., HbA1c:7.3(6.6–9.8)%). The comparison group consisted of 89 women without DM (age:58.3 (52.8–...

Research object: Since type 1 diabetic (T1D) patients are at higher fracture risk in comparison to general population the aim of study was to assess, whether femur geometric parameters are connected with Fx in T1D females.Materials and methods: We examined 68 T1D 31 yrs. old (25–37.6) females with disease duration of 11 (7–17) yrs. and the average HbA1c equal to 8.5 (6.9–10.4) %. The control group consisted of 53 healthy age- and BMI-match...

Background and aims: Type 2 diabetes is strongly associated with obesity as the major potentially modifiable risk factor. Apart from total caloric intake, certain eating patterns have been associated with the risk of diabetes and insulinoresistance. Researchers have found that specific groups in the community may be at increased risk of eating disorders, including people with diabetes and those who are obese. The aim of the study was to detect the risk of disordered eating in ...

According to the current expert recommendations it is advisable to screen microvascular complications: diabetic peripheral polyneuropathy (DPN), diabetic retinopathy (DR), diabetic nephropathy (DN) in all patients with type 1 diabetes mellitus (T1D) and disease duration of 5 years. Therefore, the aim of the study was to assess the clinical and laboratory parameters of patients with type 1 diabetes at the age of 30−45 years with duration of the disease 5–15 years, ta...

According to WHO epidemiological data, there are more than 650 million obese people in the world, the medical and social significance of which is determined by the development and aggravation of insulin resistance. Accumulation of experience in the treatment of patients with COVID-19 infection has demonstrated that obesity and diabetes mellitus are important risk factors affecting the clinical severity of inflammatory disease - for impaired function of β-cells along with ...

Background: The recommended method of initial testing for MEN2A is either a single or multi-tiered analysis to detect RET mutations in exon 8, 10, 11, 13, 14, 15, and 16.The aim of the study was to determine the relationship between the aggressiveness of the clinical course of MTC and identified mutations.Materials and methods: The research is carried out of the program ‘To develop and implement effective technologies for the ...

According to modern concepts, stress hyperglycemia and diabetes mellitus (DM) are often found in hospitals and are associated with an increase in complications, length of hospitalization and mortality. The analysis of data on the COVID-19 pandemic indicates a worse prognosis and a high risk of hospital complications in patients with DM.Aim: The aim of the study was to evaluate clinical and laboratory parameters that can be used to predict an unfavorable ...

Both hyperglycemia and in-hospital hypoglycemia are associated with poor hospital outcomes and increased healthcare costs. The effect of hypoglycemia may be due to the severity of the infectious disease and the high incidence of comorbidity. The aim of the study was to study the possible relationship between the severity, duration and compensation of hyperglycemia with the course of Covid-19.Materials and methods: A retrospective analysi...

Objective: To study the effect of parathyroidectomy (PTE) on the BMD in postmenopausal women with primary hyperparathyroidism (PHPT).Materials and methods: We studied 38 postmenopausal women with mild PHPT without osteoporosis (T-score ≥ −2,5 by DXA). In 20 patients was performed PTE, the comparison group:18 postmenopausal patients with PHPT. The duration of observation was 1 year. Examination: total calcium, Ca++, phosphorus, PTH,...

Background and aims: According to modern researchers, in patients with type 1 diabetes (T1D), the presence of diabetic osteopathy and an increasing fracture risk is evident. However, the determination of bone mineral density only is not enough to adequately assess the quality of the bone. Thus, the aim of the study was to study of the lumbar spine trabecular bone score as qualitative bone characteristic in T1DM men.Materials and methods: 52 males with T1...