Endocrine Abstracts

Assessment of basal calcitonin as the main marker of medullary thyroid cancer (MTC) was introduced into routine practice in the Republic of Belarus more than 10 years ago. A number of laboratory and clinical factors can influence the result of this parameter determination. Equally important is the gender, age, weight, the deviation of the serum calcium level, certain medications.The aim: Of the study was to develop and implement of stimulated calcitonin ...

Background and aims: Diabetic osteopathy in patients with type 1 diabetes (T1DM) is obvious. However, approaches to its diagnosis are still ambiguous. Thus, the aim was to study the features of serum osteo-specific parameters and dual energy X–ray absorptiometry (DXA) data in T1DM patients.Materials and methods: 157 patients with T1DM (105 women, 52 males) (mean age: 32.5 (25.5–41.6) yrs, duration of DM: 13 (7–20) yrs, age of manifestation...

Objective: The aim of this study is to evaluate the bone mineral density, hip geometry parameters and bone quality, measured by trabecular bone score (TBS) in patients with type 1 diabetes mellitus (T1DM).Materials and methods: We examined 97 patients with T1DM (28 males, 69 females, age: 31 (24.9−37.7) yrs., duration of DM: 11 (7−19.5) yrs., HbA1c: 8.6 (7.1−10) %, BMI: 23.1 (21.9−25.7) kg/m2). The control group consist...

Background and aims: Adipocytokines produced by adipose tissue cells, and their action is often systemic in nature. Connection of some adipocytokines (resisttin) with the development of autoimmune diseases such as type 1 diabetes (T1DM) is a perspective view. Therefore, the aim of study was to assess the association between adipocytokines (resisttin, adiponectin) and content of fat mass in T1DM.Materials and methods: Ninety-five patients with T1DM (60 wo...

The aim of the research was to reveal and assess the interaction between environmental and hereditary factors in obese patients seeking for weight loss.Materials and methods: We analysed the anamnesis of 134 overweight and obese patients, having asked to endocrinologist for losing weight (20 men and 112 women). The mean age of the respondents was 45.78+8, 76 years. 15.7% of patients were overweight, and 84.3% were obese. Heritability of obesity was deter...

Backgrounds and aim: Millions of people all over the world are in a search for the perfect weight loss plan. The aim of our research was to make a typical portrait of a Belarusian citizen who is trying to lose weight.Methods: Participants were individuals (n=70) who were screened for a behavioral weight-loss treatment program. The majority of patients were women (88.4%). The mean age was 46.56+9.43 years. Among the participants three of 70 perso...

Currently relationship between the decrease in vitamin D (VD) levels and the formation of bone pathology has established. The presence of certain VD receptor (VDR) polymorphisms has been suggested to be associated with the serum VD. Therefore, the aim of study was to assess the association between VDR single nucleotide polymorphisms (SNPs) in type 1 diabetic patients and serum VD.Materials and methods: We studied 66 type 1 diabetic (T1D) patients (28 men...

Backgrounds: The rapidly increasing epidemic of obesity is one of the most challenging dilemmas facing endocrinologists all over the world today. The scale of the obesity problem has a number of serious consequences for individuals and for government health systems. The aim of our research was the evaluation of obesity and overweight prevalence in Minsk city population within the framework of the Campaign ‘Obesity As A Risk Factor of Type 2 Diabetes Mellitus’<p c...

Background and aims: According to the risk factors study for noncommunicable diseases STEPS 2016, carried out under the auspices of the World Health Organization, in 2016–17 years 60.6% Belarusians had overweight (BMI > 25 kg/m2); 25.4% had obese (BMI > 30 kg/m2), and the proportion of women with obesity (30.2%) was 1.5 times higher than men (20.2%). Thus, the project aim was to develop a methodology for group non-drug treatment of overweigh...

Objective: In the early manifestation of type 1 diabetes (T1D) the process of bone mineralization is disrupted and the peak of bone mass is initially lower than in healthy individuals. In addition to low mineralization T1D may be a risk factor for a smaller bone size including the hip axis length (HAL). The aim of this study is to assess the HAL in women with T1D.Materials and methods: We examined 68 T1D women, age: 31(25–37.6)yrs., duration of diab...