Endocrine Abstracts

Objectives: Eating disorders often co-occur with diabetes, and this comorbidity is associated with severe medical complications. The DEPS-R is a 16-item diabetes-specific self-report measure of disordered eating that can be completed in <10 min. The purpose of the study was to translate and validate the Russian version of the Diabetes Eating Problem Survey–Revised (DEPS-R).Methods: 372 patients with diabetes mellitus using insulin injections par...

The prevalence of hypocalcemia among patients non-operated the thyroid and parathyroid glands has increased significantly with the introduction the screening of calcemia. The main reasons for hypocalcemia are hypoproteinemia and hypoparathyroidism.Objective: To study the prevalence of hypocalcemia in the adult in Minsk.Materials and methods: We studed 1207 people, average age 53.9±17.25 (892 women, 315 men) from 18 to 96 years...

Controversial data exist regarding the prevalence of eating disorders in individuals with diabetes. EAT-26 questionnaire is as a validated widely used self-reported tool recommended in general population for assessing eating disorder risk. The study aimed to determine the prevalence of abnormal eating behavior in patients with type 2 diabetes mellitus and a matched sample of nondiabetic control subjects.Research design and methods: A total 63 participant...

Introduction: The main pathogenic mechanism of bone development disease in primary hyperparathyroidism (PHPT) is speeding bone resorbtion over bone formation rate.Objective: Studying the features of bone disease in different clinical variants of PHPT.Materials and methods: We have studied 114 patients with PGPT (average age 52.19) a general medical examination has been made. The questionnaire perfomed (with the estimate of anamnest...

Objective: Patients with type 2 diabetes mellitus (DM) are expected to follow numerous dietary recommendations which can be difficult to adhere and that can cause changes in their eating behavior. Few studies have examined prevalence rates eating disorders in adults with type 2 DM despite the fact that DM is highly correlated with overweight and obesity. The aim of the study was to assess the prevalence of disordered eating behavior in type 2 diabetes mellitus patients receive...

Gestational diabetes mellitus (GDM) is a clinical condition which is ideal for evaluating short-term effects of impaired glucose metabolism, ruling out the possibility that the platelet abnormalities are a consequence of diabetic complications.The aim of this study was to measure the velocity of platelet disaggregation and the activation of the platelet second messengers cGMP and cAMP by sodium nitroprusside (SNP) and ATP, respectively, in vitro i...

Background: The central distribution of body fat has been identified as a significant risk factor for development of macrovascular complications in type 2 diabetes mellitus (T2D) in particular. The aim of the study was the features of fat mass distribution in T2D patients using insulin.Materials and methods: We studied 138 T2D patients with insulin in therapy (31 men and 107 women; mean age 51.43+8.41 yrs; disease duration 6.40+2.01 yrs...

IntroductionGhrelin has an important role in insulin resistance, glucose and lipid metabolism and cardiovascular morbidity and mortality. It is still unclear whether insulin and glucose per se play a direct inhibitory role in ghrelin secretion. The decrease in ghrelin levels after an oral glucose load is modulated by sex, status of obesity, and level of insulin resistance. The aim of our study was to evaluate gender differences in ghrelin levels in type ...

Background: MEN 2b is a highly penetrant disease with an autosomal dominant pattern of inheritance. It includes medullary thyroid carcinoma, pheochromocytomas, and multiple mucosal neuromata. The common feature of all of these tumors is a neuroectodermal origin. Although the clinical phenotype is present in all patients, individual manifestations have a variable presentation and are age dependent. Aim.: We report a case of a patient with possible MEN 2b ...

To analyze the data of relatives of first-degree patients operated on for medullary thyroid cancer (MTC), we analyzed the anamnestic data of the database of patients with MTC, formed on the basis of the cancer registry of the Republic of Belarus and medical records of the Republican Thyroid Tumor Center. Further examination of relatives is also performed on the basis of the Republican Center for Thyroid Tumors.The aim: of the study was to create a databa...