Endocrine Abstracts

Aim: To show that height loss is more correlated with vetebral micoarchitecture than with Bone Mineral Density (BMD). Material and Method: A. DEXA: made with a GE-Lunar Prodigy Pro # 500074. Vertebral microarchitecture was investigated by Trabecular Bone Score (TBS). TBS software: TBS iNsight®, version 3.0.2.0.B. Patients. 902 patients, 844 (93.6%) women, 58 men. Only 42 under 50 years. Age av...

AimTo show that height loss is more correlated with vetebral micoarchitecture than with Bone Mineral Density (BMD).Material and methodA. DEXA. Made with a GE-Lunar Prodigy Pro # 50 0074. Vertebral microarchitecture was investigated by Trabecular Bone Score (TBS). TBS software: TBS iNsight, version 3.0.2.0. B. Patients. 784 patients, 737 (94%) women, 47 men. Only 38 under 50 years. Age average: 66.04 years. Wo...

Background: Antidiuretic analogue desmopressin was tested in its intranasal form in renal colic, with variable effects.Aims: We evaluated the effects of sublingual desmopressin in lithiasic renal colic, alone or combined with a non-steroidal antiinflammatory drug (NSAID).Materials and methods: Our prospective single-blind study included an initial number of 371 patients with lithiasic renal colic randomized as follows: group NSAID ...

Background: Excess mortality after hip fracture remains a problem of public health concern. Until present, for Romania no data is available regarding long term mortality rate and excess mortality after hip fracture. We aimed to evaluate the mortality rate 3 years after hip fracture and also standardized mortality rates of osteoporotic hip fracture in the capital city of Romania and suburban area.Methods: we collected data from over 98 % of fractures admi...

Background: A large body of evidences have demonstrated that metabolic surgery is associated with significant and durable weight loss as well as a significant improvement of obesity-related comorbidities. The aim of our study was to evaluate the long term impact of gastric sleeve on metabolic parameters in morbidly obese patients.Materials and methods: We evaluated 95 (67 women) severely obese patients (mean age 43.4±10.69 years) before and approxim...

Introduction: While the unfavourable metabolic consequences of obesity have been clearly demonstrated at a population level, there is a wealth of evidence indicating the existence of individuals somehow protected from developing complications, named ‘metabolically healthy obese’. The aim of our study was to identify clinical and biological parameters independently associated with ‘metabolically healthy’ status.Patients and methods: 44...

Introduction: The most common cause of Cushing’s disease is ACTH secreting tumours of the pituitary gland. It is associated with high morbidity and mortality. Pasireotide, a potential therapy, has a unique, broad somatostatin-receptor–binding profile, with high binding affinity for somatostatin-receptor subtype 5.Case report: We present the a 40-years-old man diagnosed in 2005 with Cushing’s Disease for which a left adrenalectomy was perfo...

Introduction: Idiopathic hypercalciuria is a risk factor for nephrolithiasis. Both renal stones and hypercalciuria are often associated with lower bone mineral density (BMD), but the relationship between these modifications is not completely understood. We aimed to evaluate some metabolic particularities possibly related to relapsing nephrolithiasis in young male patients.Methods: We performed a cross-sectional study including a group of 30 young male pa...

Introduction: Adiponectin is an adipocyte-derived hormone with an important role in regulation of glucose and lipid metabolism. Its variation might mediate an ameliorated metabolic profile associated with weight loss after bariatric surgery. The aim of our study was to evaluate adiponectin change as early as 6 months after laparoscopic sleeve gastrectomy (LSG) and to indicate preoperative factors that might influence its dynamic.Methods: A number of 88 e...

It is known that thyroid pathology is generally more frequently found in women than in men. The somatotroph axis stimulates skeleton growth, but also the development of smooth tissues, including the thyroid gland. We investigated the effect of chronic GH excess upon ultrasound-evaluated (7.5 MHz linear probe) thyroid gland morphology of 74 patients (40 women şi 34 men) diagnosed with acromegaly. When compared to mean thyroid volume of age- and sex-matched non-acromegali...