Searchable abstracts of presentations at key conferences in endocrinology

ea0075r04 | Reproductive Endocrinology | EYES2021

Serum prolactin levels interact with menstrual fluctuations of arterial stiffness

Armeni Eleni , Delialis Dimitrios , Georgiopoulos Georgios , Augoulea Areti , Stergiotis Stefanos , Kontou Loraina , Chatzivasileiou Panagiota , Rizos Demetrios , Kaparos George , Baka Stavroula , Paschou Stavroula A , Mavraganis Georgios , Patras Raphael , Panoulis Konstantinos , Stamatelopoulos Kimon , Lambrinoudaki Irene

Objective: Prolactin has been adversely associated with arterial function in postmenopausal women but its vascular effects in reproductive women are unknown. Furthermore, although both circulating prolactin levels and markers of vascular function follow menstrual cycle (MC) phases, their possible inter-correlation has not been explored.Methods: Sixty healthy premenopausal women were evaluated in two distinct phases of their MC (follicular, F and luteal p...

ea0081p732 | Thyroid | ECE2022

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in advanced thyroid cancer (TC) patients; single-center experience

Simeakis George , Paschou Stavroula A. , Alevizaki Maria , Saltiki Katerina

Objectives: Patients suffering from pulmonary or/and neoplastic disease are at higher risk of developing serious illness from SARS-CoV-2. TC patients with lung metastases are classified as high-risk for severe CoV-2 disease. Aim of this study was to investigate SARS-CoV-2 prevalence and severity in this particular subgroup of patients.Methods: Out of 28 patients with metastatic Differentiated Thyroid Cancer (DTC) and 21 patients with met...

ea0049ep214 | Bone & Osteoporosis | ECE2017

Efficacy and safety of bisphosphonate discontinuation in postmenopausal osteoporosis: a systematic review

Anagnostis Panagiotis , Paschou Stavroula , Mintziori Gesthimani , Lambrinoudaki Irene , Goulis Dimitrios

Introduction: The maximum period of bisphosphonate use has not been determined, as their long-term appliance has been associated with adverse effects, such as osteonecrosis of the jaw (ONJ) and atypical femoral fractures (AFF).The aim of this study was to systematically present existent data regarding the effect of bisphosphonate discontinuation on fracture risk and bone mineral density (BMD).Methods/design: MEDLINE, Scopus, EMBASE...

ea0049ep423 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

High incidence of glucose metabolism disorders in patients undergoing coronary angiography without history of diabetes

Paschou Stavroula A , Kiokas Sotirios , Avdikos Grigorios , Lazaris Efstathios , Vryonidou Andromachi

Introduction: The aim of this study was to investigate the incidence of glycemic disorders in patients undergoing coronary angiography with no prediagnosed type 2 diabetes (T2D), as well as the association of the glycemic status with the extent of the coronary artery disease (CAD).Patients and methods: We studied 170 consecutive patients (134M/36W), 63.9±13.1 (23–95) years old, with not known T2D, who underwent coronary angiography. HbA1c was m...

ea0022p347 | Diabetes | ECE2010

Quantitative and qualitative changes in T regulatory lymphocytes (Tregs) in newly-diagnosed patients with type 1 diabetes

Paschou Stavroula , Vartholomatos George , Kolaitis Nikolaos , Papadopoulos George , Tsatsoulis Agathocles

Introduction: T regulatory lymphocytes (Tregs) are defined as CD4+CD25high T lymphocytes and are thought to regulate immune tolerance. The Foxp3 protein level in Tregs is proportional to CD25 protein surface expression and regulatory function, but inversely proportional to IL-7R (CD127) level, the receptor for the growth and survival of T cells. We investigated possible differences in Tregs between newly diagnosed type 1 diabetes (DM1) patients and contro...

ea0056p196 | Bone ' Osteoporosis | ECE2018

Recurrent vertebral fracture after denosumab discontinuation in a male patient with severe osteoporosis

Anagnostis Panagiotis , Paschou Stavroula , Potoupnis Michael , Tsiridis Eleftherios , Goulis Dimitrios

Introduction: Discontinuation of denosumab may rarely lead to rebound fractures, although the evidence is low, since available data have derived from case reports and post-hoc analyses.Case presentation: A 45-year old Caucasian male was presented at the outpatient clinic in February 2016 for evaluation and management of severe osteoporosis, which had been complicated with multiple vertebral low energy fractures at the 10 th to 12th ...

ea0099p379 | Thyroid | ECE2024

Autoimmune endocrinopathies in patients with relapsing and remitting multiple sclerosis

Chatzi Sofia , Georgakopoulou Vasiliki , Paschou Stavroula , Boutzios Georgios

Introduction: Patients with multiple sclerosis (MS) demonstrate, in a number of studies, increased risk of acquiring another autoimmune disease compared to general population. Autoimmune thyroid diseases, type 1 diabetes, psoriasis and inflammatory bowel disease are the most common reported. The aim of our study is to determine potential factors that affect the presence of autoimmune endocrinopathies in patient with relapsing and remitting MS.Methods: We...

ea0067o63 | Oral Presentations | EYES2019

Flash Glucose Monitoring technology in the management of children and adolescents with type 1 Diabetes leads to improved glycemic control

Kosteria Ioanna , Arkoumani Maira , Paschou Stavroula A , Vassilakis Ioannis-Anargyros , Kanaka-Gantenbein Christina

Objective: Flash Glucose Monitoring (FGM) is becoming increasingly popular among children with Type 1 diabetes. Our aim was to evaluate real-life data from children using FGM followed in our center.Methods: We studied 37 patients (51.4% males), with a mean±S.D. age of 10.1±3.9 years at FGM start for a period of 10.1±6.5 months. HbA1c, BMI z-score, number of self-reported and severe hypoglycemias, total insulin daily dose/kg ...

ea0049ep1139 | Female Reproduction | ECE2017

Diagnostic performance of non-invasive markers for the presence of nonalcoholic fatty liver disease in premenopausal women with and without polycystic ovary syndrome

Vassilatou Evangeline , Lafoyianni Sophia , Vassiliadi Dimitra-Argyro , Ioannidis Dimitrios , Paschou Stavroula , Mizamtzidi Maria , Vryonidou Andromachi

Introduction: Several markers based on anthropometric and biochemical parameters like fatty liver index (FLI), lipid accumulation product (LAP) index and visceral adiposity index (VAI), have been proposed for the detection of nonalcoholic fatty liver disease (NAFLD).Objective: To evaluate the diagnostic performance of FLI, LAP and VAI as markers of NAFLD in premenopausal women with and without polycystic ovary syndrome (PCOS), assessed for hepatic steato...

ea0041ep785 | Obesity | ECE2016

Interventional changes of thyroid hormone levels do not affect circulating irisin levels in humans

Panagiotou Grigorios , Pazaitou-Panayiotou Kalliopi , Komninou Despina , Paschou Stavroula A. , Kalogeris Nikolaos , Vryonidou Andromachi , Mantzoros Christos S.

Introduction: Thyroid hormones and irisin increase energy expenditure and induce browning of adipose tissue. However, little is known about irisin physiology and regulation. Here we aim to elucidate whether thyroid hormones alter circulating irisin concentrations in humans.Design and subjects: One cross-sectional (case-control) evaluation and two interventions were performed independently from each other, including previously thyroidectomized patients. C...