Endocrine Abstracts

Introduction: U-300 glargine is a new generation long acting insulin. Nocturnal hypoglicemia and weight gain with U-300 glargine is lower than U-100 glargine. However, it may take 3–4 days for U-300 glargine to reach stable state in plasma. We report a diabetic case with recurrent ketosis after U-300 glargine.Case presentation: A 20 years old woman with type 1 diabetes mellitus who uses basal and bolus insulin (U-300 glargine and insülin aspart...

Introduction and aims: Polycystic ovary syndrome (PCOS) is a frequent endocrinopathy among with young women. It is known that insulin resistance is encountered in the vast majority of the women with PCOS and hence the risk of type 2 diabetes mellitus and coronary artery disease are increased. These cardiac and metabolic risk increments may also associated with hyperandrogenemia and dyslipidemia. The metabolic changes of lipid profiles in young women with PCOS are not completel...

Introduction and aim: Cabergoline, a long-lasting dopamine-agonist, is generally considered to be the safety drug for the treatment of prolactinoma. But, use of long time and high dose cabergoline may be a cause of cardiac valvulopathy in patient with prolactinoma. In present study, we aim to determine serum N-terminal probrain natriuretic peptide levels in patients with prolactinoma who were treated with cabergoline.Materials and methods: Thirty patient...

Introduction: The aim of this study, left ventricular systolic and diastolic function by echocardiography and tissue Doppler echocardiographic evaluation and relationship serum N-terminal pro-B-type brain natriuretic peptide (NT-proBNP) levels of women with polycystic ovary syndrome (PCOS).Materials and method: Thirty-two women with PCOS (age: 23.4–4.6 years; BMI: 23.8–4.8 kg/m2), similar age and BMI have features 30 healthy womens c...

Introduction: Hyperthyroidism is associated with asymptomatic hypercalcaemia due to increased calcium mobilization from bone and catecholamine metabolism. Hypercalcaemia secondary to hyperthyroidism coexist with decreased or normal parathyroid hormone level. We reported case of 30-year-old man who suffered from Graves’ disease and primary hyperparathyroidism.Case report: A 30-year-old male patient was admitted to our hospital suffered from palpitati...

Introduction and aim: Congenital adrenal hyperplasia (CAH) is rare autosomal recessive disease. CAH due to 21-hydroxylase deficiency accounts for 95% of cases. We aim to define in this report 59-year-old woman with simple virilizing type CAH who diagnosed granulosa cell tumour and I172N mutation in the CYP21A as well as triple translocation involving chromosome 9p, 11p and 12p at first time in the literature.Case report: A 59-year-old woman was applied t...

Introduction and objective: Cardiovascular mortality is high in acromegaly. Our aim in this study was to determine the levels of the new cardiovascular marker in active acromegaly patients, the mean platelet volume (MPV) values before and after octreotide acetate long-acting repeatable treatment.Material and methods: Thirty-six patients with active acromegaly who presented at the Endocrinology Department (mean age 46.0±14.0 years and mean BMI: 30.4&...

Aim: Hashimoto’s thyroiditis (HT) is an autoimmune disease in which a breakdown of immune tolerance is caused by interplay of a variety of immunologic, genetic, and environmental factors. Mean platelet volume (MPV) is the measure of platelet size. MPV possibly is a simple way to estimate platelet activity. Activated platelets play an important role in the pathogenesis of vascular disease especially coronary heart diseases. Larger platelets are metabolically and enzymatica...

Introduction and objective: Platelets play an important role in the development of thrombotic events. Increase of mean platelet volume (MPV) may indicate pre-thrombotic conditions as a new cardiovascular marker. Larger platelets have been reported to be metabolically more active than smaller ones. Our aim of present study is to evaluate MPV levels in patients with papillary thyroid cancer.Materials and methods: Forty-seven patients with newly diagnosis m...

Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and ...