Endocrine Abstracts

Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and ...

Objective: Treatment of diabetic foot ulcer is complex and difficult. Blood glucose regulation, debridment and surgical revascularization are used in management of diabetic foot ulcer. Intralesional Epidermal Growth Factor (EGF) is a new treatment approach for diabetic foot ulcer. We report our experience with eight patients with diabetic foot ulcer who were treated by intralesional EGF.Patients and methods: A total of eight patients whose diabetic foot ...

Objective: Diet, lifestyle changes, medical agents and surgical approaches are treatment options in obese patients. We reported two morbid obese patients who lost 25 and 21% of their previous weight respectively with only lifestyle changes and orlistat therapy.Case 1: Forty nine year-old woman had type 2 diabetes mellitus for 20 years. She took premix insulin twice a day. Her height was 157 cm, her weight was 120 kg, body mass index was 48.6 kg/m2</...

Introduction and aim: Overt thyroid dysfunction is well recognized to affect weight, but the influence of minor perturbations of thyroid function remains unclear. There is ongoing debate regarding the influence of minor changes in thyroid hormones status within the normal range and BMI. The aim of this study was to investigate the association between thyroid function within normal ranges and obesity via BMI and body compositions analyzed by bioelectrical impedance.<p class...

Aim and objective: The aims of this study were to determine the incidence of breast cancer molecular subgroups, to investigate the relationship between autoimmune thyroid disease and prognostic and predictive factors in patients who were diagnosed with breast cancer.Materials and methods: One hundred one patients who were followed up with the diagnosis of breast cancer at our Endocrinology and Medical Oncology Departments were included. Patients are divi...

Background and aim: Pheochromocytoma, is a catecholamine-producing tumor, may rarely secrete other hormones such as adrenocorticotropic hormone (ACTH). We aimed to report a rare case of ectopic cushing syndrome due to malignant pheochromocytoma.Case report: A 42-year-old man admitted to outpatient clinic with headache, irritability, vomiting, nausea, and palpitation. He had paroxysmal hypertension and urinary fractionated metanephrines were measured appr...

Introduction and aims: It is known that obesity is associated with retinal microvascular changes. Optical coherence tomography (OCT), a new imaging technique, is used to visualize the choroid. In addition, OCT can also give more beneficial information about systemic and eye diseases. We aim to investigate whether or not obesity may impact on choroid and macula thickness.Material and methods: Forty-four subjects who were apply for obesity in our Endocrino...

Introduction and aim: Mean platelet volume (MPV) is a new important indicator of platelet activity in atherosclerosis. Elevated MPV is associated with the presence of more metabolically active platelets. The aim of our study is to evaluate whether change of MPV value is associated with cabergoline treatment in patients with prolactinoma.Materials and methods: Thirty patients with prolactinoma (mean age 33.4±8.5 years and body mass index (BMI): 28.1&...

Background and aim: Acromegaly is a rare endocrine disease and is associated with an increased prevalence of colorectal cancer and pre-malignant tubular adenomas, and also may be associated with other organ malignancies such as breast and thyroid. We report a rare case of acromegaly concomitant with adenocarcinoma arising from pancreas.Case report: A 52-year-old man who was diagnosed with acromegaly two years ago referred our outpatient clinic. After dia...

Aim: Mean platelet volume (MPV), which is a determinant of platelet function, is an independent risk factor for atherosclerosis. The aim of this study is to evaluate MPV values in gestational diabetes mellitus (GDM).Material and methods: Forty-nine women with gestational diabetes mellitus (mean age 28.2±4.7 years) and 40 healthy pregnant women (mean 26.2±4.6 years age) who came to our Out-Patient Clinic of Endocrinology were included in the stu...