Endocrine Abstracts

Aim: In this study, we aimed to determine the strain index (SI) as well as the ES scoring of thyroid nodules, and establish the role for these parameters in the differential diagnosis of thyroid nodules using histopathological analysis as a reference standart.Materials and method: Real-time ES in transverse axis (TA) and longitudinal exis (LA) was performed in 391 nodules of 292 patients. ES scoring was made for all the nodules. SI in TA and LA was calcu...

Aim: We aimed to determine strain index (SI) values using Elastosonography (ES) in histopathologically confirmed differentiated thyroid carcinomas (DTC) and investigate the role of these values for the differential diagnosis of nodular thyroid diseases.Material and method: ES in longitudinal axis (LA) was performed in 391 thyroid nodules of 292 patients. ES scores of thyroid nodules were determined and SI in LA for each nodule was calculated. The finding...

The relation between obesity and diabetes mellitus is known for long periods and this relation is based on insulin resistance. Recent studies showed that epicardial adipose tissue thickness measured by echocardiography is the marker of the visceral adipose tissue and cardiovascular risk. Visfatin is a new described adipokine and it has been showed to have mRNA expression in epicardial adipose tissue. There is a conflict about the role of visfatin on obesity, insulin resistance...

Introduction: Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) belongs to TNF family and is released from inflammatory cells. It has been reported that TWEAK has several biological actions ranging from cell proliferation to stimulation of apoptosis. In in vitro studies, it was reported that TWEAK has alleviating effect on insulin resistance in hepatocytes. TWEAK decreases insulin resistance induced by TNF-a through activation of phosphatase 2A pathway in a...

Aim: We aimed to evaluate wrist and ankle measurements in patients with and without diabetes-related macrovascular disease.Material and method: 151 consecutive patients with type 2 diabetes who came to our diabetic outpatient clinic were included. We have divided the patients into two groups. Group 1 (patients with diabetes related macrovascular complications) and group 2 (patients without diabetes related macrovascular complications). Group 1 (n</em...

BackgroundMucormycosis is an opportunistic fungal infection that can be aggressive and mortal. Diabetic ketoacidosis(DKA) is a risk factor for mucormycosis. We present a case with mucormycosis presenting with newly diagnosed diabetes mellitus and DKA.Case presentationA 34-year-old male patient presented with confusion and vomiting. He had no comorbiditiy. On admission the patient was afebrile, hypotensive (85...

BackgroundOur aim was to compare the effectiveness of five different risk-stratification systems using the ultrasonographical features of thyroid nodules in determining malignant histopathology.MethodsThe preoperative ultrasonography (US) features of 6925 nodules of 3030 patients who underwent thyroidectomy between 2007 and 2014 were analyzed retrospectively. The nodules were classified according to Kwak-TIRA...

Background We aimed to determine clinicopathological features that can predict lymph node metastasis (LNM) in papillary thyroid microcarcinomas (PTMC).MethodsMedical records of 872 patients with papillary thyroid cancer >1 cm (PTC >1 cm) and 1184 patients with papillary thyroid microcancer (PTMC) (£1 cm) were reviewed retrospectively. Demographical, clinical and histopathological features of (PTC >1 cm) ...

ObjectiveRadioactive iodine (RAI) therapy is widely used in both diagnosis and treatment of benign and malignant thyroid diseases. It is generally a well tolerated therapy. Bone marrow suppression is often a temporary side effect with a decrease in white blood cells and platelets up to 6–10 weeks. In this study, we aimed to examine hematological changes in patients who received RAI treatment for benign or malignant diseases of the thyroid.<p cla...

Introduction: Fibrodysplasia ossificans progressiva (FOP), also known as stone man disease, is a rare connective tissue disorder with a prevalence of 1 in 2 million. It is caused by a mutation in ACVR1 gene, usually sporadic and sometimes with autosomal dominant (AD) inheritance. These patients are normal at birth except for the short great toes and hallux valgus. Over time soft tissues such as ligaments, skeletal muscles or tendons ossify. Diaphragm, tongue, extraocular and c...