Endocrine Abstracts

Background: Pregnancy is a state of insulin resistance that can predict diabetes development in some women, and is associated with increased risk for neonate and for mother. Frequency of glucose intolerance may be increased in the follow-up years.Aim: The aim of this study is to determine the presence of risk factors for type 2 diabetes and degree of glucose tolerance in population of pregnant women.Materials and methods: The study...

Introduction: The prevalence of hyperlipidemia in type 1 diabetics is 30 to 90%. High total cholesterol, LDL and triglyceride serum level is independent risk factor for cardiovascular disease. High prevalence of malignant atherogenic profile is alarming in type 1 diabetics (high triglyceride, low HDL). It is very often that dislipidemia is associated with diabetes and obesity, as well as hypertension, that pointed to inherited disorders.The aim of this s...

Background: The levels of maternal thyroid hormone concentrations increase from early pregnancy, with a mild increase in free hormones in the first trimester with a corresponding lowering of serum TSH. Thyroid autoantibodies are found in 5–15% of women during childbearing age, and chronic autoimmune thyroiditis is the main cause of hypothyroidism. Thyroid hormone contributes critically to normal fetal brain development. In the first trimester, the ‘normal’ range...

Background: Pregnancy presents a state of insulin resistance that can predipose diabetes development in some women, and is associated with increased risk for neonate and for mother. Gestational diabetes is a period of glucose intolerance that manifests at the beginning of the third trimester.Aim: The aim of this study is to analyse glycoregulation in healthy pregnant women.Materials and methods: This study included 77 healthy pregn...

Introduction: High total cholesterol (tChol), LDL and trygliceride (TAG) level is independent risk factor for cardiovascular disease. High prevalence of malignant atherogenic profile is alarming in type 2 diabetics (high triglyceride, low HDL). It is very often that dislipidemia is associated with diabetes and obesity, as well as hypertension.Aim: The aim of this study is to analyse lipid profile in patients with type 2 diabetes in Kragujevac depending o...

Hyperlipidemia is common among patients with ST-elevation myocardial infarction (STEMI) and is associated with high risk of mortality and morbidity. Hypertriglyceridemia and low HDL cholstereol are independent risk factor for cardiovascular disease.Aim: The aim of this study is to analyse lipid profile in patients with STEMI with and without diabetes.Material and methods: This study included all patients registered in Coronary Unit...

Introduction: Thyroid disease in pregnancy is a common clinical problem, at least 2–3% of women have thyroid dysfunction, and it is estimated that about 5–20% of women of reproductive age suffer from autoimmune thyroid disease. Subclinical thyroid disease during pregnancy may be associated with adverse outcomes. In the first trimester, the ‘normal’ range for TSH is reduced to 0.1–2.5 mIU/l, and in the second and third trimester is 3.0 mIU/l.<p clas...

Introduction: Pregnancy as a state of insulin resistance can predict diabetes development in some women, and is associated with increased risk for adverse outcome of neonate and for mother.Aim: The aim of this study is to analyse pregnancy outcome in relation to a disorder of glucose tolerance during pregnancy.Matherial and methods: The study included 77 healthy pregnant women in third trimester registered in Center for endocrinolo...

High admission plasma glucose (APG) levels after ST-segment elevation acute myocardial infarction (STEMI) are common and associated with an increased risk of death in subjects with and without known diabetes.Aim: The aim of this study is to analyse the short and long term prognostic significance of APG in patients with STEMI with and without diabetes.Material and methods: This study included all patients registered in Coronary Unit...

Background: Diabetes mellitus is a condition of chronic hyperglicemia (as well as metabolic disorders of the other carbohydrates, lipids and proteins), as a result of absolute and/or relative lack of insulin or lack of insulin effects. The aim of the research presented in this study is examination of antropometric characteristics of patients suffering from type 1 diabetes in Kragujevac depending on gender.Material and method: We examined 206 patients wit...