Endocrine Abstracts

In recent years, there has been an increase in patients with metabolic syndrome (MS), which is an urgent medical problem. The severity of the clinical manifestations of MS affects the quality of life of patients, while reducing physical and mental health. Obesity leads to anxiety and depressive disorders, neurosis–like conditions, which contributes to a worsening prognosis of the underlying disease.The aim of the work was to assess the level of anx...

The prevalence of MS in different countries is 25–30% and varies depending on the diagnostic criteria used. The severity of the clinical manifestations of MS affects the quality of life (QL) of patients, while the indicators of physical and mental health decrease. The problem of QL of patients suffering from overweight and obesity is relevant and socially significant. Obesity leads to anxiety-depressive disorders, neurosis-like conditions, which contributes to a worsening...

Introduction: Metabolic syndrome (MS) is a common disease with up to 25% of the total adult population and more than 45% of those over 60 years of age. When MS develops a complex of metabolic disorders that contribute to the development of vascular atherosclerotic diseases, such as abdominal obesity, hypertension, insulin resistance, dyslipidemia. Exchange disorders in MS are associated with the development of inflammation in organs and vessels, while the role of neutrophils i...

Introduction: Metabolic syndrome (MS) is a disease that develops in obesity in adult patients with the development of numerous metabolic and vascular disorders. In patients with MS, the risk of developing cardiovascular diseases is increased compared to the general population by 1.78 times as a whole and 2.25 times in women. Currently, the number of overweight children and the development of metabolic complications such as fatty liver, hypertension, and type 2 diabetes are inc...

The defeat of the metabolic syndrome (MS) of young people with the development of severe vascular and diabetic complications determines the relevance of its study for the purpose of early diagnosis. Changes in blood at the preclinical stage of MS are reversible, while the main pathogenetic factors of MS are insulin resistance and dyslipidemia. The aim of the study was to assess the role of biochemical parameters in the pathogenesis of MS.Materials and me...

Ordinary complication of pregnancy is shift of hepatic excretory activity leading to cholestasis. Gallstone disease is also predominated in women. Both high prolactin (Prl) concentration and high level of liver prolactin receptors (PrlR) in normal and pregnant women were assumed to participate in obstructive cholestasis development.Using female rat model of hyperprolactinemia combined with obstructive cholestasis we aimed to investigate Prl influence on ...

Metabolic syndrome (MS) is one of the most pressing problems of modern medicine. MS is a symptom complex of impaired carbohydrate metabolism, abdominal obesity, dyslipidemia, hypertension with an increased risk of developing cardiovascular diseases and type 2 diabetes mellitus. The main reasons for the increase in the incidence of MS are a decrease in physical activity and a high-calorie diet. The prevalence of MS in different countries is 25–30% and varies depending on t...

Incretin-based therapy can improve glucose control in type 2 diabetes (T2D) with no weight gain. Usually dipeptidyl peptidase-IV (DPP-IV) inhibitors considered as weight neutral and glucagon-like peptide-1 receptor agonists are associated with weight loss. Some trials showed non-remarkable weight-lowering effect on DPP-IV inhibitors. We aimed to identify patients on DPP-IV inhibitors which are likely to achieve both outcomes either good glycaemic control or weight loss.<p ...

Objective: To determine the effects of hypoglycemia while sleeping on somnological parameters for patients with type 1 DM.Materials and methods: The study included 57 person with type 1 DM (Group 1 – patients with blood glucose levels (BGL) during sleep <3.9 mmol/l; Group 2 – Patients with BGL – from 3.9 to 10.0 mmol/l. The examination included: daily monitoring of blood glucose by ‘CGMSGold’ (‘MedtronikMINIMED’ (US...

Purpose: To reveal changes of the vegetative status, namely vegetative maintenance, vegetative reactance, and infringement of emotional status at patients with postoperative primary hypothyroidism (concerning central or total craws), the compensated treatment by levothyroxyn.Materials and methods: Sixteen persons are included in research with primary hypothyroidism with various etiology, compensated by levothyroxyn. The ages – 36–58 years, dura...