Searchable abstracts of presentations at key conferences in endocrinology

ea0090p452 | Reproductive and Developmental Endocrinology | ECE2023

The relationship between steroidogenesis and healthy eating index in polycystic ovary syndrome

Omma Tulay , Cigdem Yucel , Kızılgun Murat , Osmanlıoglu Coskun Seyma , Humeyra Zengin Fatmanur , Culha Cavit

Aim: We aimed to examine the relationship between the healthy eating index (HEI) and steroidogenesis in polycystic ovary syndrome (PCOS) patients and healthy controls.Materials and Methods: In addition to demographic records and routine biochemical tests, HEI was calculated from three-day nutritional records in the Bebis program. Adrenal steroidogenesis panel was measured by LCMS.Results: The study included 50 women with PCOS and 4...

ea0049ep1347 | Thyroid (non-cancer) | ECE2017

The impact of levothyroxine sodium treatment on dynamic thiol/disulphide homeostasis in overt hypothyroidism

Bicer Cemile , Ates Ihsan , Aydin Murat , Altay Mustafa , Topcuoglu Canan , Neselioglu Salim , Erel Ozcan , Yilmaz Fatma Meric

Objective: Thiols are organic compounds that contain sulphydryl group (-SH) and have important role in preventing oxidative stress especially in cells. The aim of our study is to investigate the relationship between hypothyroidism due to HT and the thiol disulfide homeostasis, the effect of treatment on this homeostasis and to demonstrate the utility of thiol/disulphide homestasis as a marker for assessing the damage to functional group of proteins and the oxidative balance in...

ea0037gp.07.05 | Reproduction: Female and other | ECE2015

mRNA expressions of skin steroidogenic enzymes in women with idiopathic hirsutism

Taheri Serpil , Unluhizarci Kursad , Zararsiz Gokmen , Karaburgu Sulbiye , Borlu Murat , Ozgun Tuncay , Karaca Zuleyha , Tanriverdi Fatih , Dundar Munis , Kelestimur Fahrettin

Introduction: The pathogenesis of idiopathic hirsutism (IH) is not clear. On the other hand, human skin possesses all the enzymes necessary for androgen synthesis and catabolism indicating that it is an independent peripheral endocrine organ. Thus, in the present study we aimed to investigate the mRNA expression of aromatase enzyme and the other enzymes having functional roles in the steroidogenic pathway, in freshly obtained skin tissue from subumblical skin and the arm of wo...

ea0037ep139 | Reproduction, endocrine disruptors and signalling | ECE2015

Increased circulating urocortin-3 levels is associated with polycystic ovary syndrome

Temur Muzaffer , Yilmaz Ozgur , Aksun Saliha , Ozbay Pelin Ozun , Calan Mehmet , Kume Tuncay , Karakulak Murat , Korkmaz Huseyin Anil

Purpose: This study aims to compare serum urocortin-3 levels in women with PCOS and healthy women, and establish what role urocortin-3 levels play in PCOS.Methods: Fifty-two patients with PCOS and 55 healthy women were included in the study, matched for age and BMI. Fasting blood glucose (FBG), insulin, hs-CRP, urocortin-3, and free testosterone levels of the all participants were measured. HOMA-IR was used to calculate the insulin resistance.<p clas...

ea0037ep219 | Reproduction, endocrine disruptors and signalling | ECE2015

The relationships of bisphenol A levels with leptin and adiponectin in premenopausal women

Polat Sevgi , Yurekli Banu Sarer , Kocabas Gokcen Unal , Durusoy Raika , Aksit Murat , Bozkaya Giray , Yuksel Arif , Saygili Fusun

Aim: Bisphenol A (BPA) is the most common endocrine disruptor among environmental estrogens. BPA is an ingredient that is commonly used in polycarbonate plastics. In this study, our main concern is to measure the levels of BPA in premenopausal obese women and to examine the relationship of BPA with adiponectin and leptin.Materials and methods: 47 obese women and 39 non-obese healthy women were enrolled in this study. All participants were premenopausal. ...

ea0037ep387 | Diabetes (pathiophysiology &amp; epitemiology) | ECE2015

Association of neutrophil to lymphocyte ratio with different glucose metabolism status

Ekiz Bilir Betul , Soysal Atile Neslihan , Bilir Bulent , Topcu Birol , Kara Sonat Pinar , Baykiz Derya , Aydin Murat

Introduction: Several studies have shown that prediabetic patients had increased concentrations of inflammatory markers and this association is independent of underlying obesity. Netrophil to lymphocyte ratio (NLR) is considered as a new inflammatory marker and has been studied extensively in a variety of clinical conditions especially in solid tumours and cardiovascular diseases. Studies evaluating the subclinical inflammation in prediabetes revealed positive association of s...

ea0037ep502 | Diabetes (complications &amp; therapy) | ECE2015

Disabilities of the arm, shoulder, and hand (DASH) questionnaire and diabetic complications: preliminary results

Tuzun Dilek , Bozkirli Emine Duygu Ersozlu , Oguz Ayten , Sahin Murat , Bolat Hanife , Deniz Mustafa Saygin , Akgul Omer Faruk , Gul Kamile

Aim: Disabilities of the arm, shoulder, and hand (DASH) questionnaire is a self-administered region-specific outcome instrument developed as a measure of self-rated upper-extremity disability and symptoms. The DASH consists mainly of a 30-item disability/symptom scale. In this study, we aimed to evaluate DASH questionnaire in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and 10...

ea0037ep506 | Diabetes (complications &amp; therapy) | ECE2015

Relation between psychiatric symptoms and diabetic complications: preliminary results

Tuzun Dilek , Bozkirli Emine Duygu Ersozlu , Oguz Ayten , Sahin Murat , Yilmaz Tugba , Ganidagli Berivan , Akgul Omer Faruk , Gul Kamile

Aim: In this study, we aimed to assess psychiatric symptoms in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and 107 men) who had T2DM were included as a preliminary in this study. The presence of cheiroarthropathy, Dupuytren’s contracture, tinnel sign, and tendinitis was assessed. Diabetic retinopathy was assessed by direct ophthalmoscopy. Urinary albumin excretion was de...

ea0037ep507 | Diabetes (complications &amp; therapy) | ECE2015

The diabetic hand: a forgotten complication?

Tuzun Dilek , Bozkirli Emine Duygu Ersozlu , Oguz Ayten , Sahin Murat , Sahin Irem , Demir Hakan , Inanc Elif , Ganidagli Berivan , Gul Kamile

Aim: Diabetes mellitus is a chronic metabolic condition characterised by persistent hyperglycaemia with resultant morbidity and mortality related primarily to its associated microvascular and macrovascular complications In this study our aim was to investigate the prevalence of the most frequently occurring hand complications in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and...

ea0037ep617 | Obesity and cardiovascular endocrinology | ECE2015

Intima–media thickness measurement of the carotid artery in patients with primary hyperparathyroidism

Tuzun Dilek , Oguz Ayten , Sahin Murat , Ganidagli Safa Ersen , Atay Didem , Bolat Hanife , Cabioglu Cansu Yilmaz , Celik Ahmet , Gul Kamile

Aim: The intima–media thickness (IMT) measurement of the common carotid artery is recognised as an important marker of systemic atherosclerosis. It may be useful in predicting the cardiovascular events, since it is related to the severity of coronary artery disease. The aims of this study were to analyse whether correlations exist between the IMT of the common carotid artery and the main clinical and biochemical parameters in patients with primary hyperparathyroidism (PHP...