Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep481 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

Influence of obesity and carbohydrate metabolism disorders in GLP-1 levels in women with history of gestational diabetes mellitus

Maraver-Selfa Silvia , Jose Picon-Cesar Maria , Molina-Vega Maria , Mancha-Doblas Isabel , Tinahones-Madueno Francisco

Introduction: There is a reduction of the incretin effect in patients with type 2 diabetes secondary to altered secretion of incretin hormones and/or failed of its action.Objective: To study the GLP-1 secretion pattern after an oral glucose tolerance test (OGTT) in postpartum reassessment of women with previous GDM.Materials and methods: Prospective epidemiological study of 48 women with a history of GDM. We evaluated age, history ...

ea0090ep1112 | Late Breaking | ECE2023

Metabolic Control and Perinatal Outcomes According to The Planning or Lack of Planning of The Pregnancy

Fernandez Valero Andrea , Jose Simon Frapolli Victor , Generoso Pinar Marta , Molina Vega Maria , J Tinahones Francisco , Jose Picon Cesar Maria

Objectives: To analyze the data of patients seen at the Diabetes and Pregnancy Unit, assessing the frequency of pregnancy planning and whether there are differences in the degree of metabolic control before and during pregnancy, as well as in perinatal outcomes with respect to those who do not plan. All women of childbearing age with Pregestational Diabetes Mellitus(PGDM) should receive preconception counseling to optimize glycemic control, since preconception control is assoc...

ea0063p548 | Diabetes, Obesity and Metabolism 2 | ECE2019

Microbiota changes in type 2 diabetes patients intolerant to metformin after drug reintroduction

Munoz-Garach Araceli , Diaz-Perdigones Cristina Maria , Moreno-Indias Isabel , Molina-Vega Maria , Cornejo-Pareja Isabel , Tinahones Francisco J

Introduction and objectives: Metformin (MTF) is the most used oral antidiabetic drug for the treatment of type 2 diabetes (T2D). However, intolerance to drug is frequent and limits its use. There are controversies about the cause of this problem, the gut microbiota has been proposed to be responsible. The gradual introduction of MTF could exercise an adaptation of gut microbiota that would facilitate tolerance to MTF. In this study we evaluate the metabolic changes and gut mic...

ea0056p362 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Is it useful the O’Sullivan test ≥200 to diagnose gestational diabetes mellitus (GDM)?

Molina-Vega Maria , Picon-Cesar Maria Jose , Hernandez-Garcia Carmen , Damas-Fuentes Miguel , Diaz-Perdigones Cristina , Tinahones-Madueno Francisco

Introduction: A two-step approach is usually used to diagnose GDM. At 24–28 weeks of pregnancy, a 50 g 1-hour glucose or O’Sullivan test is performed. If it is positive (≥140 mg/dl), it is followed by a 100 g-3 hours-Oral Glucose Tolerance Test (OGTT) which is considered positive if at least two or more values are ≥ of reference values (105-190-165-145 mg/dl). Despite it is not include in any clinical practice guideline, sometimes the 100 g OGTT is obviat...

ea0081p57 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Diagnosis of gestational diabetes mellitus in the COVID-19 pandemic: comparative analysis of women with positive O’Sullivan test in the same trimester of 2019 and 2020

Ignacio Martinez Montoro Jose , Jose Simon Frapolli Victor , Molina Vega Maria , Espina Sonsoles Morcillo , Suarez Arana Maria , Tinahones Francisco J. , Jose Maria , Cesar Picon

Introduction: In May 2020, during the COVID-19 pandemic, the Spanish Group of Diabetes and Pregnancy published a consensus document establishing the alternative diagnostic criteria for gestational diabetes mellitus (GDM) in case of impossibility to perform the two-step traditional approach due to the COVID-19 sanitary emergency. This study aims to compare different characteristics of pregnant women who tested positive in the O’Sullivan test in the same pregnancy trimester...

ea0081p368 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Comparative analysis of clinical, obstetric and perinatal characteristics of pregnant women according to serum levels of vitamin D

Simon Frapolli Victor Josa , Fernandez Valero Andrea , Fuentes Miguel Damas , Molina Vega Maria , Picon Casar Maria Josa , Tinahones Madueno Francisco Josa

Introduction: Vitamin D is considered a fat-soluble vitamin and a fundamental prohormone in mineral and bone metabolism, with an immunoregulatory, cardiovascular and neuroprotective effect, among others. Vitamin D can be found as vitamin D2 or ergocalciferol and vitamin D3 or cholecalciferol. The main source of vitamin D comes from ultraviolet radiation in sunlight, but it is also obtained through food. Vitamin D deficiency is very prevalent in Europe, with a significant peak ...

ea0081p240 | Thyroid | ECE2022

Development of a laboratory alerting system for the early diagnosis of thyroid dysfunction in pregnancy

Ignacio Martinez Montoro Jose , Jose Simon Frapolli Victor , Fernandez Valero Andrea , Molina Vega Maria , Cobos Andres , Tinahones Francisco J. , Jose Picon Cesar Maria

Introduction: Overt thyroid dysfunction in pregnancy without an early diagnosis and treatment may lead to an increased risk of adverse maternal and fetal outcomes. In this study, our goal was to assess the results of the development of a laboratory alerting system for the diagnosis of thyroid dysfunction in the first trimester of pregnancy. Material and methods: Observational retrospective study evaluating clinical and biochemical data from pregnant wome...

ea0081ep252 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Comparative analysis of characteristics of pregnant women with pathological oral glucose tolerance test vs negative oral glucose tolerance test in a trimester of 2019

Simon Frapolli Victor Jose , Ignacio Martinez Montoro Jose , Picon Cesar Maria Jose , Gutierrez Repiso Carolina , Suarez Arana Maria , Tinahones Madueno Francisco Jose , Molina Vega Maria

Introduction: Gestational diabetes mellitus (GDM) is the metabolic disorder most frequently associated with pregnancy, presenting important maternal and fetal implications. Strict glycemic control through lifestyle measures and/or pharmacotherapy is essential to achieve adequate obstetric-perinatal results. The objective of this study is to compare baseline characteristics and perinatal results in patients diagnosed with GDM after performing oral glucose tolerance test (OGTT) ...

ea0063p42 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Endocrine hypertension?

Maraver-Selfa Silvia , Damas-Fuentes Miguel , Cornejo-Pareja Isabel Maria , Molina-Vega Maria , Munoz-Garach Araceli , Hernandez-Garcia Carmen , Mancha-Doblas Isabel , Tinahones Francisco

An 18-years-old woman without medical history was referred for study of hypertension and an adrenal incidentaloma. The family history was significant for essential well-controlled hypertension in her father; diagnosed at 39 years-old. The patient complained of headache, asthenia, edema in lower limbs, high blood pressure values (200/150 mmHg) for one year (well controlled with losartan 100 mg/12 h, amlodipine 10 mg/24 h and doxazosin 4 mg/24 h) and marked facial acne previous ...

ea0063p105 | Calcium and Bone 1 | ECE2019

Parathyroid carcinoma: identity with diagnostic difficulties and therapeutic strategies

Maria Diaz Perdigones Cristina , Maria Gomez Perez Ana , Maria Cornejo Pareja Isabel , Munoz Garach Araceli , Damas Fuentes Miguel , Molina Vega Maria , Maraver Selfa Silvia

Blackground: Parathyroid carcinoma is a malignant neoplasm affecting 0.5 to 5.0% of all patients suffering from primary hyperparathyroidism. This cancer continues to cause challenges for diagnosis and treatment because of its rarity, overlapping features with benign parathyroid disease.Case report: 50 years-old-woman, without relevant previous history. She begins to present asthenia, weakness of lower limbs, arthralgias, cramps and appearance of a painfu...