Searchable abstracts of presentations at key conferences in endocrinology

ea0063p1124 | Reproductive Endocrinology 2 | ECE2019

Evaluation of insulin resistance and endocrine hormone parameters on etiopathogenesis of acne vulgaris, analyzing whether there is a change in insulin resistance and hormonal parameters after oral isotretinoin treatment

Kocyigit Suleyman Emre , Sahin Mustafa , Corapcioglu Demet

Introduction: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit and it can be seen on postadolescence period. Several studies show that adrenal and pituitary hormones have an important role in the pathogenesis. The studies which show the isotretinoin treatment takes effect on hormones are phenomenal in the literature. The aim of our study is to identify a hormonal alteration in the etiopathogenesis of acne vulgaris and to observe whether there is an alt...

ea0063p1168 | Thyroid 3 | ECE2019

The role of GLP-1, IGF-1 and leptin in thyroid cancer

Basibuyuk Fatma , Yuksel Seher , Sak Serpil Dizbay , Sahin Mustafa

Aim: The aim was to assess the expressions of GLP-1, IGF-1 and leptin in the paraffin sections of operated thyroid cancer and non-thyroid cancer patients, and show the relationship of GLP-1, IGF-1 and leptin receptor expressions with thyroid cancer, comparatively.Materials and Methods: This study was carried out retrospectively. The case groups consisted of 20 medullary thyroid cancer (MTC), 20 follicular thyroid cancer (FTC), 20 classical papillary thyr...

ea0070aep245 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Assessment of arrhythmia risk due to hypoglycemia with continuous glucose monitoring device and 24-hour holter monitoring

Sahin Mustafa , Keskin Caglar , Cinel Murat , Bahceci Begum , Corapcioglu Demet

Previous studies have shown increased hypoglycemia-associated cardiac arrhythmia and mortality in patients with type 2 diabetes and cardiovascular disease.In this study, we aimed to evaluate the response of gastrointestinal hormones and glucoregulatory hormones to the oral glucose tolerance test in patients who were diagnosed with reactive hypoglycemia and to evaluate the risk of arrhythmia with long-holter ECG measurements in patients with a diagnosis o...

ea0049ep1273 | Thyroid (non-cancer) | ECE2017

Evaluation of circulating irisin levels in patients with never treated overt hyperthyrodisim

Gokcay Canpolat Asena , Sahin Mustafa , Corapcioglu Demet , Emral Rıfat , Rıza Uysal Ali

Aims: Because of an increased metabolic activity and thermogenesis in hyperthyroidism, we aimed to evaluate the association of serum irisin with thyroid hormones.Methods: A total of 25 hyperthyroid patients and 24 age- and gender-matched healthy controls were enrolled. Serum irisin levels, thyroid hormones and body compositions were analyzed.Results: Serum irisin levels were significantly higher in hyperthyroid group (P&#6...

ea0041ep1009 | Thyroid (non-cancer) | ECE2016

Conjunctival impression cytology is worsened in Hashimoto’s thyroiditis without thyroid associated ophthalmopathy

Altay Mustafa , Sahin Tugba , Yildiz Zennure , Simsek Gulcin , Citirik Mehmet , Ates Ihsan , Bitiren Muharrem

Introduction: We aimed to investigate the conjunctival surface changes in Hashimoto’s thyroiditis (HT) patients and controls comparatively, and search the correlation of these changes with thyroid functions and thyroid autoantibody level in patients without thyroid associated ophthalmopathy (TAO).Methods: A total of 25 patients with HT and 33 healthy individuals were enrolled in the study. Serum TSH, fT4 and fT3 level, and anti...

ea0041ep1162 | Thyroid cancer | ECE2016

The efficacy and safety of sorafenib treatment on iodide refractory metastatic differentiated thyroid carcinomas

Sisman Pinar , Suveran Mustafa , Sahin Ahmet Bilgehan , Gul Ozen Oz , Cander Soner , Erturk Erdinc , Ersoy Canan

Introduction: Differentiated thyroid carcinomas (DTC) are originated from thyroid follicular epithelial cells and comprises %90 of all thyroid carcinomas. Researches indicate that sorafenib is more efficacious than other chemotherapeutic agents on metastatic iodide refractory DTCs.Material and methods: In our center, between 2013 and 2015, sorafenib was applied to six patients who had iodide refractory metastatic DTC. Five of the patients were female. Th...

ea0032p130 | Calcium and Vitamin D metabolism | ECE2013

Fahr’s disease with dystonia: a case report

Aydogan Berna Imge , Unluturk Ugur , Can Ferda , Sahin Mustafa , Uysal Ali Riza

Background: Fahr’s disease is a rare degenerative disorder characterized by symmetrical and bilateral intracranial calcification. Movement disorders are the most common symptoms of Fahr’s disease and dystonia is an uncommon presentation which accounts for only 8% of symptomatic patients.Case report: A 47 years old female admitted to emergency department with involuntary movements of extremities and anxiety. Neurological examination was normal e...

ea0032p391 | Diabetes | ECE2013

Atypical early onset Werner's syndrome

Aydogan Berna Imge , Yurumez Seda , Sengul Gozde , Sahin Mustafa , Baskal Nilgun

Introduction: Werner’s Syndrome (WS) is a rare autosomal recessive adult onset progeroid disorder characterized by the early onset of aged-appearance and age related metabolic disorders. Patients usually develop normally until the 3rd decades of life.Case report: We report a 27 years old female who admitted to our clinic at the age of 15 with hyperglycemia. She was diagnosed as diabetes and type 4 dyslipidemia at the age of 7 years. In her family hi...

ea0022p277 | Diabetes | ECE2010

Comparison of lymphomononuclear cell energy metabolism between healthy, impaired glucose intolerance and type 2 diabetes mellitus patients

Ozsari Levent , Karadurmus Nuri , Sahin Mustafa , Uckaya Gokhan , Ural Ali Ugur , Musabak Ugur , Kutlu Mustafa

Objective: Diabetes mellitus (DM) is a complex disease that affects many systems. The most important cells of the immune system are lymphomononuclear (LMN) cells. Here, we aimed to evaluate the energy metabolism of LMN cells in patients with diabetes and impaired glucose tolerance.Methods: We measured LMN cell energy metabolism in patients with type 2 diabetes mellitus, impaired glucose tolerance (IGT) and healthy subjects. Cells were freshly isolated fr...

ea0016p451 | Neuroendocrinology | ECE2008

Panhypopituitarism due to hemochromatosis: a case report

Ozkaya Mesut , Gisi Kadir , Cetinkaya Ali , Kantarceken Bulent , Cerit Mustafa , Sahin Murat , Koroglu Sedat

Introduction: Hemochromatosis is an iron storage disease characterized by iron deposition in parenchymal cells due to increased intestinal iron absorption. Iron overload leads to tissue damage and dysfunction particularly in the liver, pancreas, heart, joints, and pituitary gland. Panhypopituitarism is a clinical condition in which the anterior pituitary gland hormones are deficient. Herein we report a very rare case of panhypopituitarism due to hemochromatosis.<p class="a...