Endocrine Abstracts

Introduction: Graves’ ophthalmopathy (GO) varies from minor changes to visible face disfigurement which may compromise the visual capacity and the aesthetics of the patient. These deformities affect the quality of life in both functional and emotional senses. There are some questionnaires designed to evaluate the patient’s health, quality of life and relationship with a specific disease. The use of these questionnaires is recommended to improve the quality of care an...

Introduction: Vitamin D deficiency and insufficiency is highly prevalent even in young people. Vitamin D status has been linked to the BMI and insulin resistance.Aim: Determine 25(OH)D concentrations in adolescents before and after nutritional intervention program (NIP) and its relationship to BMI and metabolic syndrome (MS).Methods: We selected 256 secondary school students (127 males) aged between 12 and 16 years from Granada (Sp...

Background: Data on sexual dysfunction (SD) in cirrhotic patients are limited. Our aim was to evaluate the sexual function of patients with end-stage liver disease and to compare it with the results after liver transplant (LT) and with that of a controlled group matched by age and gender.Methods: Changes in sexual functioning questionnaire were used to evaluate SD in cirrhotic patients awaiting LT and in the post-LT setting 1 year after transplant. Clini...

Introduction: Craniopharyngiomas are benign epitelial tumors located in the suprasellar region and they are associated to several comorbidities. Our aim is to describe hormonal deficiency and complications after surgery.Design: Descriptive study of patients that underwent surgery of craniopharyngioma. Data collected included hormonal levels, clinical data and mortality. Quantitative variables with normal distribution are shown as mean and standard deviat...

The thyroid pathology is an area of special interest in our department. Hyperthyroidism represents 3.4% of the 8144 patients followed.The aim of this study is to characterize the therapeutic approach in patients with Grave’s disease (GD) and toxic nodular disease (TND).Retrospective study of 217 patients diagnosed with GD and TND, evaluated according parameters of therapeutic option, efficacy, relapse rate and associated compl...

Introduction and objective: Prophylactic central lymph node dissection (CLND) in patients with suspected papillary thyroid cancer (PTC) without evident lymph node metastasis (LNM), remains debatable. We propose to evaluate whether BRAF V600E mutation presence, could help to identify patients at risk for LMN.Methods: Retrospective study of patients with diagnosis of PTC, who underwent total thyroidectomy during 2002 and 2013 (n: 256) in our hospi...

Gestational Diabetes Mellitus (GDM) is characterized by insulin resistance accompanied byreduced beta-cell compensation to increased insulin demand, typically observed in the secondand third trimester and associated with adverse pregnancy outcomes. There is a need for abiomarker that can accurately diagnose GDM, predict onset and accurately monitor status, reducing foetal-maternal morbidity and mortality risks. To this end, circulating microRNAs(miRNAs) present themselves as p...

Justification and objectives: Gestational Diabetes Mellitus (GDM) is associated with an increased risk of Pregnancy-Induced Hypertension (PIH). Previous studies suggest a relationship between inflammatory markers and the development of PIH and obstetric and perinatal complications. The aim of the study was to establish the relationship between pro and anti-inflammatory cytokines and the development of PIH and the impact on obstetric and perinatal outcomes.<p clas...

Introduction: Data on sexual dysfunction (SD) in cirrhotic patients are limited. Sexual function is a complex area of human behavior with great impact on quality-of-life (QOL). Despite its relevance, it is rarely evaluated in clinical practice in cirrhotic patients. Indeed, published studies are heterogeneous, differ in the way sexual function is assessed, and usually evaluate only one specific aspect of sexual life. Our aim was to evaluate in detail the sexual function of pat...

The management of nonfunctioning adrenal masses is controversial. The size is usually the only criterion for surgical treatment. The objective was to study the progression of the tumor size and the follow-up of several cardiovascular risk parameters in patients with nonsurgical nonfunctioning adrenal masses.Retrospective longitudinal observational study of 24 patients (54.2% men) with nonfunctioning adenomas followed for five years without surgical treat...