Endocrine Abstracts

Introduction: Neutrophil lymphocyte rate (NLO), which is obtained from peripheric blood and used as mathematical rates of lymphocyte numbers, is accepted as available and practical indicator of systemic inflammation existence. We aimed to search NLO between Hashimoto’s thyroids patients who have autoimmune thyroid and also include an aetiopathogenesis auto-inflammatory process, and healthy control group with this study.Method: 59 patients who have b...

Introduction: We aimed to determine changes in geriatric assessment of cases with acromegaly.Methods: 26 elderly cases with acromegaly (controlled/uncontrolled: 15/11, F/M: 17/9) were included. 20 age, gender and BMI matched cases without acromegaly composed control group (CG) (F/M: 10/10). Presence of concomitant diseases and educational level were not different between the groups. Cognitive functions were evaluated with Mini Mental State Exam (MMSE), a...

Introduction: Increasing evidence suggesting an integral role of vitamin D in skeletal muscle function. The relationship between muscle strength and vitamin D status has been investigated to some degree in older populations, however there has been very little research in younger adult women. This study aims to measure the effects of vitamin D on handgrip strength in young adult women.Method: A total of 141 healthy women with mean age of 33.8±6.8 wer...

Objective: The measurement of epicardial adipose tissue (EAT) sonographically is reported to be related with both obesity and insulin resistance. Hepatic steatosis is one of the best known other coincidence with obesity. We aimed to evaluate the relationships between EAT thickness, hepatic steatosis and insulin resistance in obese patients.Methods: Obese 63 subjects were enrolled into the study. Local ethical committee approval was obtained. Patients wer...

IntroductionHypercholesterolemia may develop due to primary and secondary causes. Diabetes mellitus, hypothyroidism, nephrotic syndrome and liver diseases are among the most common causes of secondary hyperlipidemia. Here, we will present a case with severe hyperlipidemia due to primary sclerosing cholangitis(PSC).CaseA 36-year-old male patient was admitted to our outpatient clinic due to severe hypercholeste...

However ACTH secreting adenomas are one of the most common functional pituitary tumors, subtypes such as Crooke cell corticotroph adenoma(CCCA) are relatively rare. We present here a patient with CCCA who had severe hypercortisolism mimicking ectopic ACTH syndrome. A 69 years old female patient admitted to emergency department after a fall. On cranial MRI,’a 3.5x2.5x3cm mass appearance with a sellar-suprasellar location, which is compressing the optic chiasm, expanding th...

Introduction: Minimally invasive surgery is an alternative surgical approach for primary hyperparathyroidism with less surgical trauma and anesthesia complications. Neck ultrasonography and scintigraphy are still the first step tools for localisating parathyroid lesions. Intact parathyroid hormone (PH) determination in washout samples is really very useful when parathyroid lesions can not be easily distinguished from thyroid lesions or sometimes lymph nodes.<p class="abste...

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age. Clinical and biochemical characteristics are similar to metabolic syndrome. Insulin resistance in patients with metabolic syndrome, is associated with serum uric acid levels. In our study, we aimed to investigate the relationship between serum uric acid levels and clinical and laboratory in PCOS patients.Materials and Method: PCOS ...

Aim: In a previous study, we demonstrated elevated mean platelet volume in isolated hypogonadotrophic hypogonadism (IHH) is associated with high cardiovascular risk. Monocyte count/HDL-cholesterol ratio (MHR) is a new inflammatory marker showing cardiovascular risk. The purpose of this study is to evaluate (MHR) in men with hypogonadotrophic hypogonadism.Method: This study includes 31 men with isolated hypogonadotrophic hypogonadism without previous trea...

Glucocorticoid actions in the brain are mediated by glucocorticoid receptors (GR) and mineralocorticoid receptors (MR). MR and GR bind endogenously circulating glucocorticoids, share a hormone response element in DNA, and are co-expressed in neurons of the hippocampus and hypothalamus. This arrangement suggests MR and GR functionally cooperate in the regulation of gene expression though hitherto poorly described mechanisms. This possibility was previously exampled by the demon...