Endocrine Abstracts

Introduction: The heel Quantitative Ultrasound (QUS) evaluates the bone health, with good results if the clinical risk factors are also evaluated for each patient. Among these, the body mass index (BMI) may be protective or risk factor for a fragility fracture, depending on the values.Aim: We present a study in postmenpausal women evaluated by QUS and BMI.Patients & method: This is a study in 330 patients (women in menopause wh...

Background: Hirsutism is a major feature of the polycystic ovary syndrome (PCOS) and the only accepted clinical sign of hyperandrogenism for its diagnosis, according to the androgen excess society (AES) recommendations. Previous studies demonstrated that hirsutism can be influenced by factors other than hyperandrogenism per se.Aim: To detect factors influencing hirsutism severity in PCOS.Patients and methods: Hundred and sev...

Introduction: Infertility investigations include uterine–ovarian ultrasound. The incidental finding of a tumor in a young female might associate a potential severe prognosis in otherwise completely asymptomatic patient.Aim: We present a case of a young female with an accidentally discovered ovarian tumor.Case report: S.M. 35-year female patient is admitted for infertility. Her family and personal medical history is irrelevant....

Introduction: Pituitary incidentaloma is a relatively frequent imagistic finding. Since no therapy is necessary, the follow up protocol is the most important in patients’ approach.Aim: We present a study in patients diagnosed with pituitary incidentaloma, admitted in I.Parhon, Bucharest, between 1999 and 2011.Patients and method: This is a retrospective study in 140 patients, diagnosed with pituitary incidentaloma based on CT ...

Introduction: The quantitative ultrasound (QUS) is an useful tool in the evaluation of the fragility fracture risk.Aim and study design: We performed the QUS fragility fracture risk groups (valided by the golden standard DXA) by a unifactorial analyze including the bone markers.Method: The cut offs used were: SI≤59U (high risk), SI≥83U (low risk), and medium risk with SI between 59 and 83U. The QUS analyze was performed...

Introduction: Turner syndrome is a common cause of dwarfism and hypogonadism as is pituitary failure. However the association of the two is rarely thought and reported in the literature. We present two cases of women with hypogonadism diagnosed with Turner syndrome with various degrees of pituitary insuficiency.Case report: The first case presented at 16 years with secondary amenorrhea and showed slightly disharmonic dwarfism. A hypogonadotropic hypogona...

Background: Cushing’s syndrome (CS) is associated with a hypercoagulable state and an increased risk for acute coronary syndromes, stroke, and deep vein thrombosis (DVT).Aim: To assess the prevalence of thrombotic events in a series of patients with CS.Patients and methods: Notes of 113 patients with CS were retrospectively reviewed.Results: Instable angina was diagnosed in ten women, aged 52.1±12.2...

Background: Endocrine hypertension accounts for around 3% of the secondary forms of hypertension and screening of young hypertensive patients for secondary causes is mandatory.Aim: To present difficulties in endocrine assessment of arterial hypertension in people younger than 40 years.Patients and methods: Twenty-two patients (15 M/7 F), aged 27.1±7.7 years (range:16-40 years), with systemic hypertension (systolic blood pressu...

Introduction: Despite the presence of antinuclear (ANA) and anti DNA antibodies in Graves’ disease, the association with Systemic Lupus Erythematosus (SLE) is rare. Responsible for this association seem to be mutations in the PTPN22 gene.Case Report: We report a case of a 27-year-old woman, who presented in January 2009 in our department, at 6 months postpartum, after extensive investigations for autoimmune disease. She had negative results for poly...

Introduction: Phaeochromocytomas (PHEO) are tumours of the chromaffin cells and are usually detected due to the typical symptom triad including headache, palpitations and sweating associated with persistent and/or paroxysmal blood hypertension. An increasing proportion of PHEO is incidentally discovered upon abdominal imaging.Objective: To analyse the clinical characteristics of the incidentally discovered phaeochromocytomas.Method...