Endocrine Abstracts

Aim: Re-analyzing the effect of injectable testosterone undecanoat depot (TUD) in hypogonadic patients.Materials & methods: (A) Patients: at onset 191 men with hypogonadism (median age: 64 years). (B) Distribution: by decade. (C) TUD (NebidoR-Bayer-Schering) 1000 mg was injected one per 3 months i.m. (D) Prostate volume (PV) by per-abdominal ultrasound: 3.5 MHz probe, elliptical volume (cm3), Aloka 550. (E). Time of analysis: be...

Introduction: The pituitary non-secreting microadenomas (or incidentalomas) are frequently diagnosed over the last decades thanks to imagery scan progresses and access. The gonadal dysfunction, as well as other pituitary deficiency is related to common genetic backup (+/− other pituitary dysfunctions) or may be incidental.Aim: We analyzed the endocrine profile in pituitary incidentalomas (microadenomas).Material and method: A...

Introduction: The pituitary tumors which are considered pituitary incidentalomas are accidentally discovered at pituitary scan and they associate a lack of pituitary hyper-secretion. Opposite to what generally are considered for adrenal incidentalomas, the pituitary incidentalomas are more frequent with years of life.Aim: We analyzed the incidentaloma sizes related to decades of age.Material and method: This is a retrospective stud...

Background: Acromegaly is associated with increased prevalence of thyroid diseases, particularly of differentiated thyroid carcinoma.Aim: To assess prevalence of thyroid diseases and thyroid cancer in patients with acromegaly.Patients and methods: Forty (10 M/30 F) acromegalic patients, 14 residents in iodine deficient areas, aged 47±12.8 years, were retrospectively reviewed. Mean duration of acromegaly was 7.6±9.5 years ...

Aim: Analyzing the evolution of thyroid function in thyroiditis and related disease between 1–20 years.Material and method: i). Diagnostic: Hashimoto thyroiditis (HT): 1. antithyroperoxydase antibodies (ATPO), cut-off 34 ui/ml. 2. if ATPO=normal, thyroiditis was considered if high antithyroglobuline antibodies (T-ATG); 3. idiopathic mixedema (IM): hypothyroidism with no ATPO, no A...

Material and method: i). Patients: A. ‘Classical’ Hashimoto thyroiditis (hyper-ATPO-emia, HT) =1293, B. thyroiditis with isolated hyper-ATG-emia, with normal ATPO (T-ATG) =92, C. thyroiditis ‘sero-negative’ (normal ATPO and ATG, pathology diagnosis) =11, D. idiopathic myxedema (hypothyroidism, no A,B,C) =86; E. control=1219. 2. Statistical analysis: X2 test, z test.Results:...

Aim and Objectives: Is Hashimoto thyroiditis (HT) different from thyroiditis with only antithyroglobulin antibodies (T-ATG)?Material and method: i). Diagnosis: ATPO >34 ui/ml = HT; ATPO normal with high ATG (>34 ui/ml) =T-ATG. ii). Thyroid function: TSH. iii). Patients: HT=1293, T-ATG=92. iv). Statistical analysis: Student tα, linear correlation tests....

Background: Adrenocortical oncocytoma is a veryrare adrenal tumor type, usually nonfunctioning and benign. Neurofibromatosistype 1 (NF1) is an autosomal dominant disease caused by mutations of the NF1 gene encoding neurofibromin, a tumor supressor gene that acts by activating a RAS GTP-ase which negatively regulates RAS activity. NF 1 is usually associated with pheocromocytoma, rarely with adrenal carcinoma, and no association with adrenal oncocytoma has been reported.<p c...

Introduction: Primary adrenal insufficiency (PAI) is a rare disease with a prevalence of 82–144 cases/milion. The etiology of PAI is represented primarily by autoimmune adrenalitis, followed by tuberculosis and less common by fungal infections, HIV, hemorrage in adrenal glands, certain drugs and by some genetic disorders such as Triple A syndrome (AAA), Adrenoleukodystrophy (ALD), congenital adrenal hypoplasia, congenital adrenal hyperplasia, etc.C...

Background: Hyperthyroidism is widely known to be an important cause of secondary osteoporosis through the accelerated rate of bone turnover, while primary hyperparathyroidism is typically associated with loss of cortical bone and less so of trabecular bone, as seen on dual-energy x-ray absorptiometry (DXA). The evaluation of bone quality in these categories is not fully understood and needs further research. The aim of this study was to compare the bone quantity and quality, ...