Endocrine Abstracts

Bone metabolism disorders in hemodialysed patients (HD) involve several humoral factors, of which PTH plays the central role. Leptin is a protein hormon secreted by the adipocytes and related to malnutrition, anemia and bone metabolism disorders in chronic kidney disease patients. The aim of the study was to was to evaluate serum leptin levels and bone metabolism in chronic HD patients depending on body mass index (BMI). This cross section study included 93 HD patients distrib...

Introduction: In patients with type 1 diabetes (T1D), depression increases the risk for persistent hyperglycemia, diabetes complications and mortality. Most results demonstrated that depression is associated with nearly all important medical and psychosocial outcome parameters of T1D. Also, it has been demonstrated that poor diabetes self-care can result from patients’ lack of knowledge or existing psychosocial issues, primarily depression. The aim of the study was to det...

Introduction: Growth without growth hormone is seen also in patient with craniopharyngioma. We just speculate what anabolic factors might be involved in this process. However, oestrogen through its receptors lead to epiphyseal fusion. In this case report we would like to present the patient with bilateral slipped femoral epiphysis (SFE) and interventions made at tertiary health care level.Case report: 20-years-old female, operated from craniopharyngioma ...

Positron emission combined with computed tomography using 18F-deoxy-glucose (FDG–PET/CT) is increasingly used in the staging and detection of malignant disease. Normal pituitary is not visualized by routine FDG–PET/CT and its radiological evaluation relies predominantly on magnetic resonance imaging (MRI). The role of FDG–PET/CT in differential diagnosis of sellar mass, in patients investigated for malignant disease, will be discussed.<p class="ab...

Introduction and objectives: The aim of our study was to determine which characteristics of the uncontrolled diabetes are among randomly selected patients with type 1 (T1DM) and type 2 (T2DM) diabetes.Material and methods: A total of 194 diabetic patients were observed, 142 with T2DM and 52 with T1DM, recruted in outpatient clinic. Patients were divided into three groups according to HbA1c values: <7% (G1), 7–8% (G2) and >8% (G3). Statistica...

Presumption, nausea, bowel distension, abdominal pain and early satiety are very common in patients with Anorexia nervosa (AN). These problems may give rise to significant medical complications and may contribute to increased difficulties with refeeding and weight restoration. The aim of our study was to evaluate the influence of gatrointestinal treatment on weight gain in AN patients. Esophagogastroduodenoscopy with gastric mucose biopsy were performed in 19 AN patients (DSM-...

Introduction: Generously supported by IPSEN)-->Active acromegaly is reported to be associated with considerable body composition changes, with significant lean body mass changes found only in men.Patients and methods: In patients with active acromegaly (n=40) 24 females and 16 males, 48.9±6.4 years old, with BMI of 28.04±1.27 kg/m2, diagnosed 4.15±1.09 years ago, body composit...

Background: Generously supported by IPSEN)-->Hypopituitarism is considered to be a risk factor for cardiovascular disease and early death in humans. However, some studies showed that most patients with isolated GH deficiency or combined pituitary hormonal deficiency due to gene mutations (PROP 1, GH receptors gene, GH-1 gene) can survive to advanced age.Aim: To collect clinical data on patients with congenital ...

Background: Literature data regarding the prevalence of the syndromes of thyroid autoimmunity (AIT) in antiphospholipid syndrome (APS) are rather limited. However, quite frequently it is hypothesized on common pathophysiologic mechanisms underlining these disorders.Objectives: The aim of this investigation was to evaluate the frequency of disorders of thyroid function and occurrence of anti-thyroid antibodies (ATAs) among patients with antiphospholipid s...

Introduction: Clinical trials have show n that improved glycemic control reduces the incidence and progression of diabetes complications. One of the most important steps in diabetes treatment is to educate patients how to manage self monitorining blood glucose (SBGM) and adjust their life habits with their diabetes. A new diabetes management concept of structured testing is supported by Accu -Chek 360 View.Objectives: Assess the impact of structured test...