Endocrine Abstracts

Introduction: A multidisciplinary clinic has been developed to optimize the diagnosis and treatment of bone metabolism diseases. Initiated in March 2013, it is carried out simultaneously, once a week by an Endocrinologist and a Rheumatologist.Objective: To describe the experience of this unit in the last 12 months.Material and methods: Cross-sectional observational study. 235 patients were attended from December 2015 to December 20...

Introduction: The cause of primary hyperparathyroidism (PHPT) is a single adenoma in 85% of cases. Scintigraphy with technetium-sestamibi (MIBI) is the test of choice for localising adenomas in patients with PHPT, allowing minimally invasive surgery in most patients. Some articles recommend thyroid function supression to improve scintigraphy results.Methods: A prospective study was conducted in which 8 patients were included with diagnosis of PHPT and ne...

Objective: To study the relation between incretin-based therapies, DPP-4 inhibitors and GLP-1 receptor agonists, and tumor stage at the time of diagnosis of pancreatic and biliary tract cancer.Methods: Retrospective study of type 2 diabetic patients with newly diagnosed of pancreatic or biliary tract cancer attended consecutively in a tertiary hospital between the years 2012 and 2015.Results: A total of 37 patients were included. T...

Objective: To assess improvement in glycemic control in those diabetic patients who have received structured education in diabetes in our Day Hospital.Methods: A retrospective observational study was carried out in which 42 diabetic patients who had attended to educational courses in 1 year were included, determining the age of the patient, type of Diabetes, score obtained in the questionnaires at the beginning and end of the course, as well as HbA1c bef...

Introduction: Transsphenoidal surgery (TS) is used for pituitary and suprasellar tumors. It has a risk of damaging the pituitary axis and developing hypocortisolism, a potential life threating risk.Objetive: Incidence of hypocortisolism after TS, postsurgery cortisol (PSC) levels that predict hypocortisolism and potential risk factors for hypocortisolism after TS.Methods: Prospective study in patients who underwent TS in 2016. Gluc...

Introduction: 39% of morbidly obese patients have type 2 diabetes mellitus (T2DM) and 80% of them can achieve diabetes remission after bariatric surgery. However, there are few randomized studies comparing the metabolic results of different surgical techniques and the hormonal mechanisms involved.Objective: To study and compare the improvement of T2DM and the hormonal pathways following three surgical techniques: metabolic gastric bypass (mGBP), sleeve g...

Introduction: Recent studies have pointed out a possible role of vitamin D in carcinogenesis. Vitamin D deficiency may be related to a major cancer incidence and mortality. This association would be more relevant for breast and colorectal cancer. Obesity acts as a risk factor for these type of neoplasms on which vitamin D could influence.Subjects and methods: A cross-sectional study of consecutive out-patients with newly diagnosed cancer: urological, col...

Introduction: It is known that about 75% of cases of endogenous Cushing síndorme to a pituitary adenoma (HA) ACTH-producing, 15% to ectopic ACTH and 10% is due to adrenal adenoma.Case: The patient was 64 years old, derived from Diabetes Mellitus type 2 of about 16 years of history with an unwieldy+hypertension diagnosed in 2007 with no physical signs compatible with hypercortisolism and incidentally detected a left adrenal adenoma 2 cm. Hormonal blo...

Introduction: Diabetes Mellitus (DM) and prediabetic states (pre-DM) are well known risk factors for stroke. Admission blood glucose level and its control during hospital stay, help predicting arterial recanalization after thrombolysis and middle and long term prognosis. We analysed recurrence, mortality and nosocomial infectious complications in DM, pre-DM and patients without previous or newly diagnosed DM or pre-DM.Methods: Descriptive analysis in con...

Objectives: This study evaluated the prebiotic effect of a moderate intake of extra virgin olive oil (Evoo) and red wine (Rw) polyphenols on modulating the gut microbiota composition and the improvement of metabolic risk factors in obese subjects with high insulin resistance (HIR).Methodology: 10 obese patients with HIR (HOMA-IR>5.5) and 10 lean subject with low insulin resistance (HOMA-IR< 3.3) were included in a randomized and controlled interv...