Endocrine Abstracts

Introduction: The number of transgender men and women who seek gender-affirming therapy is rapidly increasing worldwide. It is still a population at high risk for several morbidities. The Basque Country Gender Identity Clinic was created in 2009 to centralize their medical care in the region.Aim: To determine the proportion of transgender individuals in the Basque Country, the prevalence of several morbidities in this transgender population, their evolut...

Background: The goals of acromegaly treatment are to achieve long-term biochemical control, control tumor size and decrease the risk of developing systemic comorbidities. Moreover, from the patient’s perspective, symptoms and QoL are critical parameters of disease control and should be assessed routinely. To aid in the global clinical management of acromegaly, a holistic clinical decision support tool, the Acromegaly Disease Activity Tool (ACRODAT®) was developed.</p...

Introduction: Lymphocytic hypophysitis is a strange cause of hypopituitarism which can represent a difficult diagnostic and therapeutic challenge.Objectives and methods: Describe the diagnosis, evolution and treatment of a case of lymphocytic hypophysitis in a patient who began with hypopituitarism and a year after the diagnosis had local symptoms. We reviewed the medical history of the patient from the moment the patient contacted with us to the months ...

Introduction and objectives: The inhalation of tobacco smoke leads to an acute increase in cortisol, ACTH and GH concentration, both in chronic smokers as in non-smokers. However, most studies have failed to demonstrate differences between both groups in basal levels of these hormones in plasma or urine. Additionally, cholinergic pathways have been shown to play an inhibitory role in ACTH secretion in non-smokers. UFC and circulating levels of cortisol, ACTH and GH were evalua...

Introductions: Alterations of the somatotrophic and hypothalamic–pituitary–adrenal (HPA) axes occur frequently in patients with poorly controlled DM-1. These disorders could be related to abnormalities in the cholinergic tone regulating both hormonal axes.Subjects and Methods: UFC (urinary free cortisol) on 24 h urine samples and the effects of placebo and pyridostigmine on ACTH, cortisol, GH and glucose circulating levels were studied in 16 yo...

Introduction and Objectives: In patients with poorly controlled DM-1, the frequently observed alterations of somatotrophic axis seem to be related to abnormalities in the hypothalamic cholinergic tone regulating this axis. The effects of cholinergic stimulation on GH responses to GHRH were evaluated in patients with poorly controlled DM-1 and the relationship of these responses to metabolic control and kidney function tests.Subjects and Methods: Microalb...

Introduction: Adrenocortical carcinoma (ACC) is a very rare neoplasm with an incidence of about one case per million population. It is an agressive tumor (overall 5-year survival 16–38%) and complete resection is the only curative treatment.Description of methods: We report four cases of ACC. The clinical and biochemical features at diagnosis along with clinical course of the disease are discussed.Results: Four patients (three...

Objectives: The prevalence of diabetic patients admitted in hospitals close to 20% in some series. Our goal is to determine the prevalence of diabetic patients assessed by interclinical calls from different medical and surgical specialties that have been entered during 2015 in our Hospital, in order to describe the characteristics that these diabetic patients.Material and methods: We present 116 patients evaluated by interclinical consultation request fo...

Objectives: To evaluate the prevalence of hypertension in patients with type 2 diabetes mellitus (T2DM) and to analyze the clinical characteristics, the degree of achieved control and the associated antihypertensive treatment.Methods: Cross-sectional study which included patients with T2DM followed in a primary care setting. Data about age, sex, associated antihypertensive treatment, systolic blood pressure (SBP) and diastolic blood pressure (DBP) was co...

Objectives: To evaluate the prevalence of cardiovascular disease (CVD) and associated risk factors in patients with type 2 diabetes mellitus (T2DM) attended in a rural primary care setting.Methods: Cross-sectional study which included patients with T2DM followed in a rural primary care setting. Data about several cardiovascular risk factors was collected (age, sex, smoking, hypertension and dyslipidemia). Also, data about coronary heart disease (CHD) and...