Endocrine Abstracts

Introduction: Evaluation of postmenopausal hyperandrogenism may be a challenge for physicians as it is necessary to exclude the presence of the relatively rare but potentially life-threatening underlying tumorous causes. We report the case of a postmenopausal woman who presented with clinical and biochemical hyperandrogenism.Case Report: We present the case of a 65 year-old woman being followed at our clinic because of mild hypothyroidism. At inspection ...

This study was conducted to evaluate the frequency of PCOS in a group of FTM transsexual persons and its relationship between clinical, hormonal and metabolic characteristics.Subjects and Methods: We studied 21 FTM cases, aged 17–37 years, BMI 24.6±5.2. No patient reported previous hormonal treatment or sex re-assignment surgery. PCOS was diagnosed according to the Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group, 2004. World Health...

Introducción: Thyroid nodule is a very frequent pathology that affects 4-8% of population. Fine-needle aspiration (FNA) guided by ultrasound (US) is considered the gold standard test in diagnostic evaluation of thyroid nodules. This technique is being assumed more and more frequently by endocrinologists.Description of Methods: We conducted a retrospective study that included all thyroid US-guided FNA performed in 2014. We considered the following va...

Introduction: Our objective is to determine the profile of patients with differentiated thyroid cancer (DTC) attended in our center and the therapeutic approach employed.Methods: Retrospective review of medical records from patients treated for DTC during the years 2013 and 2014.Results: Data from 387 patients, 84% female, 96% Caucasian, mean follow up of 10.82 years. The average age at diagnosis was 44.24 years, 77% had normal thy...

Introduction: Roux-en-Y gastric bypass (RYGB) places patients at an increased risk of hypocalcemia due to the reduction in calcium absorption (because the procedure bypasses the duodenum and jejunum) and vitamin D deficiency. Subsequent thyroid surgery increases the risk of severe hypocalcemia due to potential post-operative hypoparathyroidism. Only a few cases have been published before of this kind of treatment-challenging hypocalcaemia.Case report: We...

Introduction: Cinacalcet is an oral calcimimetic indicated in treatment of primary hyperparathyroidism in patients who are unable to undergo parathyroidectomy: do not accept surgery, there is failure of previous surgery or serious comorbidity that makes surgery impossible.Methods: Descriptive study that includes nine patients with primary hyperparathyroidism who have completed at least 48 months of treatment with cinacalcet (seven patients refusal to par...

Background: The prevalence of unawareness hypoglycaemia in patients with type 1 diabetes mellitus (T1DM) is uncertain. This study aims to determine its prevalence and predictive clinical characteristics with greater precision.Methods: Prospective study. 128 patients were recruited between September 2013 and January 2014. Awareness of hypoglycaemia was assessed using the ‘Clarke’ questionnaire and was classified into two groups, depending on the...

Objective: To describe the clinical characteristics of stroke in patients with prediabetes mellitus (pre-DM) and to compare them with DM and non-DM patient characteristics.Methods: Retrospective analysis of a prospective series of acute stroke patients. Demographic and clinical characteristics were compared among the three groups, along with outcome data. Stroke severity was evaluated by modified Rankin scale (mRS) and NIHSS (NIH stroke scale).<p cla...

Objective: To describe the clinical, aetiological and prognostic differences in diabetic and non-diabetic ischaemic stroke (IS) patients.Materials and methods: Retrospective analysis of prospective series of IS patients. Patients were classified as non-DM and DM patients. Demographic and clinical characteristics were compared between two groups. IS prognosis was evaluated by modified Rankin scale (mRS) and NIHSS (NIH stroke scale)....

Introduction: Diabetes mellitus is a condition on the increase, carrying a high risk of macro and microvascular disease. Previous studies suggest a link between microvascular and macrovascular complications in diabetes. However, just a few studies have investigated whether the presence of peripheral vascular disease (PVD) is associated with other macrovascular and microvascular complications in diabetes patients. So, this was the aim of our study.Patient...