Endocrine Abstracts

Background/purpose: The combination of DM and HT accelerates vascular complications and increases the risk of mortality and morbidity. Hypertension is seen in half of diabetic patients. HT can be detected in approximately 40% of newly diagnosed diabetic patients. DM frequency increased 2.5 times in hypertensive patients. The association of HT and DM is due to the common mechanism responsible for the pathogenesis of both diseases. There is a limited number of studies investigat...

Introduction: U-300 insulin glargine has been used as a concentrated form of glargine. Skin and subcutaneous tissue disorders (eg, rash, pruritus, and urticaria) have been reported with insulin glargine. But to our knowledge, maculopapular rash has not been reported with use of U-300 insulin glargine. We present a patient with type 1 diabetes mellitus(DM) developing maculopapular rash after initiation of U-300 glargine insulin.Case Report: 37 year-old fe...

Introduction: Thyroid nodules are extremely common. By age 60, about one-half of all people have a thyroid nodule. Cryoablation is used in a variety of clinical applications, using hollow needles (cryoprobes). Cryoprobes are inserted into or placed adjacent to diseased tissue which is desired to be ablated.Objectives: To evaluate the effect of Cryoablation on the size & function of thyroid nodule, which may replace the need for surgery or radiotherap...

Case report: 21-year-old female patient visited the emergency department with repeated attacks of vomiting accompanied with continuous non radiating epigastric pain diagnosed as acute pancreatitis. She had three plasmapheresis sessions. She gave history of recurrent similar attacks for the last 5 years with frequent hospitalization she is known diabetic since the age of 15.Hypertensive for 1 year. Menarche at age of 14 with only one cycle. Upon admission, the patient was alert...

The commonest cause of hypercalcaemia is primary hyperparathyroidism (PHPTH). The diagnostic work up includes paired blood samples for serum corrected calcium, parathyroid hormone (PTH) and vitamin D levels. But in young patients, rare genetic conditions could be contributing towards hypercalcaemia and hence could produce a diagnostic challenge. We report hypercalcaemia work up in two young females where genetic tests were required.Case 1<p class="ab...

Hypercalcaemia due to primary hyperparathyroidism (PHPTH) is fully curable by parathyroidectomy. Occasionally recurrent hypercalcemia presents as a results of either residual adenoma, recurrent disease or an ectopic parathyroid gland. The most challenging cases are those with ectopic glands which are not identified on usual surgical neck exploration. We present a similar case that went through multiple surgeries for recurrent hypercalcemia. A 79-year-old lady initially was dia...

The incidence of recurrent primary hyperparathyroidism (PHPTH) (> 6 months from initial exploration) has been reported to be between 1–10%. Repeated neck explorations could be challenging for surgeons and ensuring normalised biochemistry is vital for peri-operative safety. Recurrent parathyroid adenomas can present with aggressive hypercalcaemia which can be challenging to control prior to surgery. We report a similar case below. A 72 year old lady had her first prese...

IntroductionCerebral tuberculomas are a rare form of tuberculosis due to the hematogenous spread of Mycobacterium Tuberculosis (MT). Pituitary localization is exceptionally uncommon with total reported cases in the literature fewer than a hundred. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the rare case of a patient diagnosed with a primary pituitary stalk tuberculosis.Observation...

A 41 year old lady presented to emergency department with tremors and palpitations. Her examination and routine bloods were normal but ECG showed sinus tachycardia (heart rate = 141 bpm). She was treated with propranolol and discharged. She was readmitted in emergency department with ongoing palpitations, lethargy and tremors. On examination, she had a diffuse goitre but no signs of Graves’ eye disease. The blood tests showed overt thyrotoxicosis (TSH<0.01 mU/l, FT4 =...

Introduction: The association between papillary thyroid carcinoma and thyroiditis was first reported in 1955 by Daily, in 2023 if this association is well established, it still continues to be talked about. Does cancer precede thyroiditis or does thyroiditis induce cancer and when the two combine does cancer have a better prognosis?Material and methods: We report a prospective study carried out in a hospital center in Algeria between 2020 and 2022 which ...