Endocrine Abstracts

Background: We aimed to determine and compare the prevalence and associated factors of metabolic syndrome (MS) among HAART exposed versus HAART naïve HIV infected patients at the Aminu Kano Teaching Hospital, Kano (AKTH).Method: In this cross-sectional comparative study we evaluated 300 HIV infected persons who were divided into two age and sex matched groups – HAART-exposed and HAART-naïve – attending AKTH. MS was diagnosed using ATP...

Background: The lipid profile of healthy adults in northern Nigeria is scarcely reported in literature. Yet, hospital records show increasing frequency of dyslipidemia-related illnesses like CVA, MI, and peripheral vascular diseases in practice. We aim to report the pattern of lipid abnormalities in a rural population in Kano, Nigeria.Methods: A population screening of apparently healthy adults resident in sub urban community in Kano was undertaken over ...

A small for gestational age baby boy (weighing 2.3 kg) was delivered at term by emergency section for foetal bradycardia, to a 35-year-old mother with type 1 diabetes.He was admitted with suspected sepsis because of maternal colonization with group B streptococcus. He had hyperglycaemia (6–12 mmol/l), initially attributed to sepsis and was treated as such. Hyperglycaemia persisted, despite treatment and being clinically well.F...

Introduction: It has been shown that type 2 diabetes mellitus (T2DM) could affect bone metabolism through several mechanism and it may increases risk for osteoporosis. Glucose lowering therapies including metformin has also been reported to may effect on bone turnover. This study aimed to evaluate the effects of metformin therapy on bone resorption and formation markers in newly diagnosed patients with T2DM.Method/design: Study population consisted of 37...

Aim: To describe the clinical characteristics and outcomes of hospitalized COVID-19 patients with diabetes.Methods: A retrospective cross-sectional study was conducted among patients admitted to the William. Harvey Hospital in England between March 10th and May10th, 2020 with a laboratory confirmed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), known as COVID19. Variation in characteristics, length of stay in hospital, diabetes status, dur...

Introduction: Both endothelial dysfunction and albuminuria have been shown to be related to cardiovascular risk. We aimed to investigate relations between endothelial dysfunction, albuminuria and frequency of the microvascular complication in type 2 diabetic patients.Method: Forty type 2 diabetic patients (24 microalbuminuria and 16 macroalbuminuria) with a mean age of 57.2±10.8 years and 25 healthy control subjects with a mean age of 54.1±9.6 ...

Objective: To determine the Predictors of growth response to GH treatment in a group of isolated idiopathic GH (GH).Patients and methods: 477 GH deficient (GHD) children with GH therapy were included in the study. Patients were followed up for a minimum of 1 year up to 6 years. Multiple linear regressions were done to identify predictors of growth response to rhGH in the first 4 years of treatment.Results: In the first year, three ...

Nicotine (N) is known as the main toxic and addictive component of cigarette smoke. By its ability to generate reactive oxygen species (ROS) and oxidative damage in organism, it can induce major public health problems such as cancer, cardiovascular diseases and infertility. Green tea extract (GTE) is an important source of polyphenols catechins; it has attracted a great deal of attention around the world because of its potential antioxidants role in scavenging free radicals. T...

Background: There is accumulating evidence suggesting that altered vitamin D may play a role in the development of T2DM. A growing body of evidence suggests that low levels of vitamin D may adversely affect the cardiovascular system.Objective: This is to assess the relation of serum 25 OH vitamin D concentrations and risk of CVD in T2DM patients.Subjects and methods: Seventy subjects aged from 40 to 60 years were chosen excluding t...

We have recently explored the involvement of ghrelin in the eating response to stress in humans and found that ghrelin levels increased in parallel to cortisol after a standardized psychological stress. To further elucidate this interaction, we examined the ghrelin response to pharmacological manipulation of the HPA axis.Following approval from the local Ethical Committee, six lean, healthy male volunteers were examined on two occasions. Blood samples we...