Endocrine Abstracts

Cellular transplantation has enormous potential for treating a variety of degenerative or malignant conditions. While adult stem cells display limitations in expansion capacity and developmental potential, embryonic stem (ES) cells are an inexhaustable source of tissues for research and therapy. During the last decade, human ES cells have been isolated, and differentiated to several tissue-specific progenitors. In vitro differentiating ES cells recapitulate early steps ...

We report of two sisters with hyperandrogenism, menstrual abnormalities, and severe insulin resistance. The elder sister was seen after puberty at age 21 and she was referred for the evaluation of hirsutism and polymenorrhoea; the younger was seen earlier in life, at age 15, for the evaluation of secondary amenorrhoea. In both of them, we performed the diagnosis of polycystic ovary syndrome (PCOS) in accordance to the Rotterdam criteria. They also presented a lipodystrophic ph...

All adolescent and young adult T1DM attending our clinic, based in a university teaching hospital are reviewed three monthly and receive individual advice from dietician, nurse educator and consultant diabetologist at each visit. We aimed to identify deficits in diabetes related knowledge and assess diabetic control in this population.Subjects were asked to complete ADKnowl(Audit of Diabetes Knowledge) Questionnaire. Demographic data and measures of glyc...

Background: The paediatric diabetes team at our Children’s Hospital were part of a national clinical trial considering whether long term outcomes are better for patients on MDI (multiple daily injection therapy) or insulin pump therapy from diagnosis. Patients and their families had to be approached, consented and treatment for the trial commenced within two weeks of diagnosis. Many centres struggled to recruit, but this was not the case with our centre.<p class="abst...

Background: Most obesity management programs use short term weight loss as the main monitoring parameter. Change in weight can be a misleading measure as it can be impacted by various factors and most participants regain weight after exiting such programs1. The aim of this project is to assess the efficacy of focusing on self-selected, non-weight loss goals in encouraging long term obesity management.Methods: ...

This will be a personal reflection by an ‘experienced’ clinician who has spent much his consultant career in clinical management including 4 years as Medical Director of a large Acute Trust. I will try and highlight the advantages and benefits of being involved in clinical management for you the Clinician, the Trust and your Patients. I will also outline some of the problems and pitfalls that can arise but I will focus on how this career choice can be developed and b...

This will be a personal reflection by an ‘experienced’ clinician who has spent much his consultant career in clinical management including 4 years as Medical Director of a large Acute Trust. I will try and highlight the advantages and benefits of being involved in clinical management for you the Clinician, the Trust and your Patients. I will also outline some of the problems and pitfalls that can arise but I will focus on how this career choice can be developed and b...

This talk will focus on contraceptive options for patients with polycystic ovary syndrome (PCOS). Key considerations for clinicians will be explored, including the choice of appropriate formulations for cycle regulation, control of symptoms of androgen excess and suppression of dysfunctional menstrual bleeding. Other issues covered during this session will include contraceptive options in patients with obesity or at high risk of complications such as venous thromboembolism, as...

Congenital gonadotropin-releasing hormone deficiency is a rare disorder characterized by incomplete or absent puberty and infertility. This condition is both clinically and genetically heterogeneous and presents with a broad spectrum of phenotypes ranging from mild to severe. This presentation will provide a review of hypogonadotropic hypogonadism, including the clinical presentation of HH, a rational approach to evaluating HH patients, and an update on treatment options. In p...

IntroductionThe choice of a specialty in medicine is a decision that is imposed on new graduates. The aim of our study was to assess the perception of the specialty of Endocrinology and Nutrition among a large sample of medical students in their final year of their degree or prior to taking their Medical Internship Examination in order to know if they would choose Endocrinology and Nutrition for their specialised training, as well as the most and least a...